TCM Putative Target References: TCMH1999


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC903
TCMT175 G-protein coupled bile acid receptor 1 Homo sapiens IC50: 6000 (nM), Ref: 20801037
TCMC1758
TCMT247 Alpha-2a adrenergic receptor Homo sapiens Ki: 66 (nM), Ref: 8632424
TCMC1758
TCMT243 Alpha-2c adrenergic receptor Homo sapiens Ki: 63 (nM), Ref: 8632424
TCMC1758
TCMT559 Beta-2 adrenergic receptor Homo sapiens Ki: 3300 (nM), Ref: 27132867
TCMC1758
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 1300 (nM), Ref: 27132867
TCMC1477
TCMT273 Bile acid receptor FXR Homo sapiens IC50: 7860 (nM), Ref: 23688559
TCMC1477
TCMT162 UDP-glucuronosyltransferase 1-1 Homo sapiens IC50: 5600 (nM), Ref: 21030469
IC50: 4900 (nM), Ref: 21030469
TCMC1830
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 930 (nM), Ref: 15357969
TCMC1830
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 2600 (nM), Ref: 15357969
TCMC1830
TCMT808 Fatty acid binding protein epidermal Homo sapiens IC50: 1200 (nM), Ref: 15357969
TCMC1830
TCMT809 Fatty acid binding protein intestinal Homo sapiens IC50: 1700 (nM), Ref: 15357969
TCMC1830
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1830
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC453
TCMT588 D-amino-acid oxidase Homo sapiens Ki: 156 (nM), Ref: 23391306
IC50: 943 (nM), Ref: 23391306
IC50: 440 (nM), Ref: 23391306
IC50: 34.67 (nM), Ref: 23631755
Ki: 13 (nM), Ref: 23631755
TCMC1504
TCMT273 Bile acid receptor FXR Homo sapiens IC50: 18.3 (nM), Ref: 24775917
TCMC1498
TCMT864 Thyroid hormone receptor alpha Homo sapiens IC50: 0.24 (nM), Ref: 16099653
IC50: 0.24 (nM), Ref: 17543524
Ki: 0.33 (nM), Ref: 18975928
Ki: 2.33 (nM), Ref: 22542282
Ki: 2.33 (nM), Ref: 23276448
IC50: 3.2 (nM), Ref: 24290064
TCMC1498
TCMT69 Thyroid hormone receptor beta-1 Homo sapiens IC50: 0.26 (nM), Ref: 16099653
IC50: 0.26 (nM), Ref: 17543524
IC50: 0.257 (nM), Ref: 17524652
Ki: 0.68 (nM), Ref: 18975928
Ki: 2.29 (nM), Ref: 22542282
Ki: 2.29 (nM), Ref: 23276448
IC50: 2.9 (nM), Ref: 24290064
TCMC1498
TCMT796 Proliferating cell nuclear antigen Homo sapiens IC50: 3600 (nM), Ref: 23395113

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC903
TCMT1251 Candida albicans Candida albicans MIC: 64 (ug/ml), Ref: 18805690
TCMC903
TCMT1246 Escherichia coli Escherichia coli MIC: 64 (ug/ml), Ref: 18805690
MIC: 7.81 (ug/ml), Ref: 20181416
MIC: 4 (ug/ml), Ref: 20038628
MIC: 8 (ug/ml), Ref: 20038628
MIC: 16 (ug/ml), Ref: 20038628
TCMC903
TCMT1232 Pseudomonas aeruginosa Pseudomonas aeruginosa MIC: 15.63 (ug/ml), Ref: 20181416
TCMC903
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 31.25 (ug/ml), Ref: 20181416
TCMC885
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 3.1 (ug/ml), Ref: 7381838
MIC: 0.8 (ug/ml), Ref: 7381838
MIC: 4 (ug/ml), Ref: 2933519
MIC: 1 (ug/ml), Ref: 2933519
MIC: 0.5 (ug/ml), Ref: 3373488
MIC: 0.5 (ug/ml), Ref: 2502627
MIC: 4 (ug/ml), Ref: 3877809
MIC: 4 (ug/ml), Ref: 2933520
MIC: 0.3 (ug/ml), Ref: 3701783
MIC: 20 (ug/ml), Ref: 2724308
MIC: 10 (ug/ml), Ref: 17825955
MIC: 8 (ug/ml), Ref: 19027993
MIC: 2 (ug/ml), Ref: 19027993
MIC: 4 (ug/ml), Ref: 19027993
MIC: 1 (ug/ml), Ref: 19027993
MIC: 4.6 (ug/ml), Ref: 20211890
MIC: 3.9 (ug/ml), Ref: 20211890
MIC: 2.5 (ug/ml), Ref: 20211890
MIC: 10.7 (ug/ml), Ref: 20211890
MIC: 3.1 (ug/ml), Ref: 20211890
MIC: 3.3 (ug/ml), Ref: 20211890
MIC: 3.8 (ug/ml), Ref: 20211890
MIC: 14.7 (ug/ml), Ref: 20211890
MIC: 6.6 (ug/ml), Ref: 20211890
MIC: 10.6 (ug/ml), Ref: 20211890
MIC: 1.25 (ug/ml), Ref: 894680
MIC: 5 (ug/ml), Ref: 894680
MIC: 1.25 (ug/ml), Ref: 894679
MIC: 5 (ug/ml), Ref: 894679
MIC: 1.6 (ug/ml), Ref: 392100
MIC: 6.2 (ug/ml), Ref: 392100
MIC: 4.5 (ug/ml), Ref: 21963
TCMC885
TCMT1176 Streptococcus pneumoniae Streptococcus pneumoniae MIC: 1.6 (ug/ml), Ref: 7381838
MIC: 4 (ug/ml), Ref: 2933519
MIC: 0.5 (ug/ml), Ref: 3373488
MIC: 2 (ug/ml), Ref: 3877809
MIC: 2 (ug/ml), Ref: 2933520
TCMC885
TCMT1448 Enterobacter aerogenes Enterobacter aerogenes MIC: 25 (ug/ml), Ref: 7381838
MIC: 5 (ug/ml), Ref: 894680
MIC: 5 (ug/ml), Ref: 894679
MIC: 6.8 (ug/ml), Ref: 21963
TCMC885
TCMT1170 Enterobacter cloacae Enterobacter cloacae MIC: 25 (ug/ml), Ref: 7381838
TCMC885
TCMT1246 Escherichia coli Escherichia coli MIC: 6.2 (ug/ml), Ref: 7381838
MIC: 8 (ug/ml), Ref: 3373488
MIC: 1 (ug/ml), Ref: 3701783
MIC: 2 (ug/ml), Ref: 18180352
MIC: 12.5 (ug/ml), Ref: 894680
MIC: 12.5 (ug/ml), Ref: 894679
MIC: 6.2 (ug/ml), Ref: 392100
MIC: 8.5 (ug/ml), Ref: 21963
TCMC885
TCMT1226 Klebsiella pneumoniae Klebsiella pneumoniae MIC: 3.1 (ug/ml), Ref: 7381838
MIC: 16 (ug/ml), Ref: 3373488
MIC: 3.1 (ug/ml), Ref: 392100
MIC: 7 (ug/ml), Ref: 21963
TCMC885
TCMT1224 Proteus mirabilis Proteus mirabilis MIC: 12.5 (ug/ml), Ref: 7381838
MIC: 4 (ug/ml), Ref: 3373488
MIC: 6 (ug/ml), Ref: 18180352
MIC: 4 (ug/ml), Ref: 18180352
MIC: 3 (ug/ml), Ref: 18180352
MIC: 2 (ug/ml), Ref: 18180352
MIC: 1.5 (ug/ml), Ref: 18180352
MIC: 1 (ug/ml), Ref: 18180352
MIC: 12.5 (ug/ml), Ref: 894680
MIC: 12.5 (ug/ml), Ref: 894679
MIC: 25 (ug/ml), Ref: 392100
TCMC885
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 32 (ug/ml), Ref: 2933519
MIC: 32 (ug/ml), Ref: 3877809
MIC: 32 (ug/ml), Ref: 2933520
MIC: 12.5 (ug/ml), Ref: 392100
TCMC885
TCMT1177 Haemophilus influenzae Haemophilus influenzae MIC: 8 (ug/ml), Ref: 2933519
MIC: 4 (ug/ml), Ref: 3373488
MIC: 8 (ug/ml), Ref: 3877809
MIC: 8 (ug/ml), Ref: 2933520
TCMC885
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 32 (ug/ml), Ref: 3373488
MIC: 64 (ug/ml), Ref: 2502627
MIC: 64 (ug/ml), Ref: 19027993
TCMC885
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 1 (ug/ml), Ref: 3701783
MIC: 1 (ug/ml), Ref: 19027993
TCMC885
TCMT1194 Shigella sonnei Shigella sonnei MIC: 5 (ug/ml), Ref: 894680
MIC: 5 (ug/ml), Ref: 894679
TCMC885
TCMT1195 Streptococcus pasteurianus Streptococcus pasteurianus MIC: 1.6 (ug/ml), Ref: 392100
TCMC885
TCMT1196 Salmonella Salmonella MIC: 6.2 (ug/ml), Ref: 392100
TCMC885
TCMT1197 Shigella sp. Shigella sp. MIC: 9 (ug/ml), Ref: 21963
TCMC1830
TCMT1361 Neisseria meningitidis Neisseria meningitidis MIC: 50 (ug/ml), Ref: 19884363
TCMC1830
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 3.8 (ug/ml), Ref: 20855214
IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830
TCMT1442 Leishmania donovani Leishmania donovani IC50: 14.5 (ug/ml), Ref: 20855214