Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
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| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
|---|---|---|---|---|
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TCMT59 | Apoptosis regulator Bcl-X | Homo sapiens |
IC50: 500 (nM), Ref: 13678404 Ki: 480 (nM), Ref: 17034116 Ki: 1000 (nM), Ref: 25797160 Ki: 620 (nM), Ref: 25818766 Ki: 640 (nM), Ref: 26421995 IC50: 2720 (nM), Ref: Ki: 770 (nM), Ref: 26620718 Ki: 310 (nM), Ref: 27353532 |
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TCMT47 | Apoptosis regulator Bcl-2 | Homo sapiens |
Ki: 320 (nM), Ref: 17034116 IC50: 500 (nM), Ref: 17034116 Ki: 170 (nM), Ref: 17552510 IC50: 2110 (nM), Ref: 23474389 Ki: 558 (nM), Ref: 24095762 Ki: 560 (nM), Ref: 26620718 Ki: 431 (nM), Ref: 26982372 Ki: 440 (nM), Ref: 27353532 |
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TCMT61 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens |
Ki: 180 (nM), Ref: 17034116 Ki: 280 (nM), Ref: 17552510 IC50: 1523.1 (nM), Ref: Ki: 190 (nM), Ref: 23314054 Ki: 213.8 (nM), Ref: 23314054 IC50: 4800 (nM), Ref: 23314054 IC50: 170 (nM), Ref: 23314054 Ki: 190 (nM), Ref: 24095762 Ki: 310 (nM), Ref: 26421995 Ki: 390 (nM), Ref: 26620718 Ki: 260 (nM), Ref: 26982372 |
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TCMT82 | Estrogen receptor alpha | Homo sapiens | IC50: 2551.34 (nM), Ref: |
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TCMT95 | DNA-3-methyladenine glycosylase | Homo sapiens |
IC50: 3000 (nM), Ref: 25650313 |
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TCMT96 | L-lactate dehydrogenase A chain | Homo sapiens |
Ki: 1900 (nM), Ref: 26340601 |
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TCMT97 | L-lactate dehydrogenase B chain | Homo sapiens |
Ki: 1400 (nM), Ref: 26340601 |
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TCMT206 | Cytochrome P450 2A6 | Homo sapiens |
IC50: 3920 (nM), Ref: 15658857 |