Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC172	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 310 (nM), Ref: 23332346
TCMC658	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 122 (nM), Ref: 26125082
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1957	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 78 (nM), Ref: 26125082
TCMC1258	TCMT37	Serotonin 2a (5-HT2a) receptor	Homo sapiens	Ki: 966 (nM), Ref: 25695425
TCMC1258	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 43 (nM), Ref: 25695425
TCMC1258	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 171 (nM), Ref: 25695425
TCMC1424	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2100 (nM), Ref: 17994701
TCMC1748	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 85 (nM), Ref: 16562853 Ki: 314 (nM), Ref: 25695425
TCMC1748	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 373 (nM), Ref: 25695425
TCMC1748	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 20 (nM), Ref: 25695425
TCMC1748	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 306 (nM), Ref: 25695425
TCMC1748	TCMT646	Serotonin 5a (5-HT5a) receptor	Homo sapiens	Ki: 566 (nM), Ref: 25695425
TCMC1748	TCMT313	Serotonin 2b (5-HT2b) receptor	Homo sapiens	Ki: 323 (nM), Ref: 25695425
TCMC315	TCMT46	Coagulation factor III	Homo sapiens	IC50: 14.98 (nM), Ref: 23199480
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC6	TCMT46	Coagulation factor III	Homo sapiens	IC50: 152.43 (nM), Ref: 23199480
TCMC6	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 50 (nM), Ref: 23332346
TCMC6	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 305 (nM), Ref: 23332346
TCMC6	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 149 (nM), Ref: 23332346
TCMC2053	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 22 (nM), Ref: 23332346
TCMC2053	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 214 (nM), Ref: 23332346
TCMC162	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 1189 (nM), Ref: 23332346
TCMC264	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 105 (nM), Ref: 23332346
TCMC264	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 6.6 (nM), Ref: 23332346
TCMC2105	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2105	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC2150	TCMT46	Coagulation factor III	Homo sapiens	IC50: 22.78 (nM), Ref: 23199480
TCMC2150	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 231 (nM), Ref: 23332346
TCMC858	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 66 (nM), Ref: 23332346
TCMC858	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 119 (nM), Ref: 23332346
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC38	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 529 (nM), Ref: 23332346
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC429	TCMT853	Sigma opioid receptor	Homo sapiens	Ki: 106 (nM), Ref: 27032890
TCMC429	TCMT651	Dopamine D3 receptor	Homo sapiens	Ki: 37 (nM), Ref: 27032890
TCMC429	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 102 (nM), Ref: 27032890
TCMC429	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 15 (nM), Ref: 27032890
TCMC1655	TCMT643	Alpha-1a adrenergic receptor	Homo sapiens	Ki: 430 (nM), Ref: 15664832
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC234	TCMT615	Sentrin-specific protease 8	Homo sapiens	IC50: 5470 (nM), Ref:
TCMC234	TCMT616	Sentrin-specific protease 7	Homo sapiens	IC50: 4630 (nM), Ref:
TCMC234	TCMT617	Sentrin-specific protease 6	Homo sapiens	IC50: 1860 (nM), Ref:
TCMC2146	TCMT46	Coagulation factor III	Homo sapiens	IC50: 8.35 (nM), Ref: 23199480
TCMC784	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 100 (nM), Ref: 26003344
TCMC784	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1090 (nM), Ref: 26003344
TCMC265	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 91 (nM), Ref: 23332346
TCMC265	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 4.5 (nM), Ref: 23332346

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC658	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 49.81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1957	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2346	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 25824664
TCMC2349	TCMT1183	Candida albicans SC5314	Candida albicans SC5314	IC50: 36 (ug/ml), Ref: 26394911
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC2383	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2399	TCMT1246	Escherichia coli	Escherichia coli	MIC: 8 (ug/ml), Ref: 22483632
TCMC1424	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC934	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC858	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.555 (ug/ml), Ref: 3286870 IC50: 1.739 (ug/ml), Ref: 3286870
TCMC858	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 42.71 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC946	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 14510592
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC784	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1