TCM Putative Target References: TCMFx5379


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2051
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 8710 (nM), Ref: 22892213
TCMC2051
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4050 (nM), Ref: 22892213
TCMC2051
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 960 (nM), Ref: 22892213
TCMC1107
TCMT290 Muscarinic acetylcholine receptor M5 Homo sapiens Ki: 0.14 (nM), Ref: 23707254
Ki: 0.3388 (nM), Ref: 24365159
Ki: 0.34 (nM), Ref: 24365159
Ki: 3.02 (nM), Ref: 25051097
TCMC1107
TCMT291 Muscarinic acetylcholine receptor M3 Homo sapiens Ki: 0.2692 (nM), Ref: 24365159
Ki: 0.27 (nM), Ref: 24365159
TCMC1107
TCMT292 Muscarinic acetylcholine receptor M1 Homo sapiens Ki: 0.2692 (nM), Ref: 24365159
Ki: 0.27 (nM), Ref: 24365159
TCMC1107
TCMT293 Muscarinic acetylcholine receptor M2 Homo sapiens Ki: 5.012 (nM), Ref: 25051097
Ki: 12.88 (nM), Ref: 25051097
Ki: 3.631 (nM), Ref: 25051097
Ki: 2.818 (nM), Ref: 25051097
TCMC2204
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 482 (nM), Ref: 21067924
Ki: 478 (nM), Ref: 22077347
Ki: 480 (nM), Ref: 26688270
TCMC2204
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 754 (nM), Ref: 22077347
Ki: 750 (nM), Ref: 26688270
TCMC1999
TCMT34 Cytochrome P450 2D6 Homo sapiens Ki: 3.3 (nM), Ref: 8487254
Ki: 4.6 (nM), Ref: 8487254
Ki: 14 (nM), Ref: 8487254
Ki: 5.7 (nM), Ref: 8487254
Ki: 3.5 (nM), Ref: 8487254
Ki: 13 (nM), Ref: 8487254
Ki: 4.6 (nM), Ref: 8487254

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2051
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 42 (ug/ml), Ref: 22280816
MIC: 42.1 (ug/ml), Ref: 26112067
TCMC1515
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 20542692
TCMC2550
TCMT1393 Vibrio sp. Vibrio sp. MIC: 15 (ug/ml), Ref: 21865038
TCMC2558
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans MIC: 31.2 (ug/ml), Ref: 8496702
TCMC724
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans IC50: 20 (ug/ml), Ref: 12502337
TCMC724
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 8 (ug/ml), Ref: 9748372
IC50: 36 (ug/ml), Ref: 9748372
TCMC724
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 64 (ug/ml), Ref: 21288041
TCMC724
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 64 (ug/ml), Ref: 21288041
TCMC2667
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 64 (ug/ml), Ref: 15104489
MIC: 100 (ug/ml), Ref: 20542692
TCMC2711
TCMT1251 Candida albicans Candida albicans MIC: 31.2 (ug/ml), Ref: 8496702
TCMC2711
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans MIC: 15.6 (ug/ml), Ref: 8496702