TCM Putative Target References: TCMFx3585


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC555
TCMT37 Serotonin 2a (5-HT2a) receptor Homo sapiens Ki: 15 (nM), Ref: 16392816
TCMC555
TCMT313 Serotonin 2b (5-HT2b) receptor Homo sapiens Ki: 52 (nM), Ref: 16392816
TCMC555
TCMT314 Serotonin 2c (5-HT2c) receptor Homo sapiens Ki: 42 (nM), Ref: 16392816
TCMC555
TCMT315 Serotonin 6 (5-HT6) receptor Homo sapiens Ki: 13 (nM), Ref: 16945532
Ki: 70 (nM), Ref: 10.1007/s00044-004-0121-8
TCMC555
TCMT316 Melatonin receptor 1A Homo sapiens Ki: 210 (nM), Ref: 26023814
TCMC555
TCMT317 Melatonin receptor 1B Homo sapiens Ki: 16 (nM), Ref: 26023814
TCMC876
TCMT560 Coagulation factor X Homo sapiens IC50: 720 (nM), Ref: 9834152
Ki: 450 (nM), Ref: 9834152
TCMC1624
TCMT560 Coagulation factor X Homo sapiens IC50: 280 (nM), Ref: 9834152
Ki: 690 (nM), Ref: 9834152
TCMC1286
TCMT45 Beta amyloid A4 protein Homo sapiens IC50: 3000 (nM), Ref: 25086914
TCMC1286
TCMT2 Microtubule-associated protein tau Homo sapiens IC50: 3000 (nM), Ref: 25086914
TCMC403
TCMT609 Cathepsin L Homo sapiens IC50: 2900 (nM), Ref: 22591648
TCMC90
TCMT207 Beta-secretase 1 Homo sapiens IC50: 2400 (nM), Ref: 14592472
TCMC770
TCMT588 D-amino-acid oxidase Homo sapiens Ki: 7000 (nM), Ref: 23391306
IC50: 2089.3 (nM), Ref: 23631755
Ki: 2000 (nM), Ref: 23631755

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1491
TCMT1109 Reverse transcriptase Human immunodeficiency virus 1 IC50: 0.00423 (ug/ml), Ref: 21334901
IC50: 0.00211 (ug/ml), Ref: 21334901
TCMC2324
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC2439
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 2 (ug/ml), Ref: 9784148
TCMC913
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913
TCMT1189 Pseudomonas fluorescens Pseudomonas fluorescens MIC: 1.6 (ug/ml), Ref: 14995101
TCMC946
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 100 (ug/ml), Ref: 14510592
TCMC1491
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 0.92 (ug/ml), Ref: 21334901
TCMC1491
TCMT1318 Human T-lymphotropic virus 1 Human T-lymphotropic virus 1 IC50: 1.07 (ug/ml), Ref: 21334901