Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC172	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 310 (nM), Ref: 23332346
TCMC658	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 122 (nM), Ref: 26125082
TCMC1173	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9430 (nM), Ref: 20185318 Ki: 9430 (nM), Ref: 26498394
TCMC1173	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9780 (nM), Ref: 20185318 Ki: 9780 (nM), Ref: 26498394
TCMC1173	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9870 (nM), Ref: 20185318
TCMC1173	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7410 (nM), Ref: 20185318
TCMC1173	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 8450 (nM), Ref: 20185318
TCMC1173	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7040 (nM), Ref: 20185318
TCMC1173	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2400 (nM), Ref: 20185318
TCMC1173	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2890 (nM), Ref: 20185318
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1957	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 78 (nM), Ref: 26125082
TCMC1803	TCMT337	Exportin-1	Homo sapiens	IC50: 1600 (nM), Ref: 20493693
TCMC1258	TCMT37	Serotonin 2a (5-HT2a) receptor	Homo sapiens	Ki: 966 (nM), Ref: 25695425
TCMC1258	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 43 (nM), Ref: 25695425
TCMC1258	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 171 (nM), Ref: 25695425
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC1424	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2100 (nM), Ref: 17994701
TCMC737	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 168 (nM), Ref: 26498393
TCMC737	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 5591.2 (nM), Ref: 26498393
TCMC737	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 423.7 (nM), Ref: 26498393
TCMC737	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4.9 (nM), Ref: 26498393
TCMC1748	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 85 (nM), Ref: 16562853 Ki: 314 (nM), Ref: 25695425
TCMC1748	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 373 (nM), Ref: 25695425
TCMC1748	TCMT160	Serotonin 7 (5-HT7) receptor	Homo sapiens	Ki: 20 (nM), Ref: 25695425
TCMC1748	TCMT315	Serotonin 6 (5-HT6) receptor	Homo sapiens	Ki: 306 (nM), Ref: 25695425
TCMC1748	TCMT646	Serotonin 5a (5-HT5a) receptor	Homo sapiens	Ki: 566 (nM), Ref: 25695425
TCMC1748	TCMT313	Serotonin 2b (5-HT2b) receptor	Homo sapiens	Ki: 323 (nM), Ref: 25695425
TCMC1104	TCMT678	Inhibitor of apoptosis protein 3	Homo sapiens	IC50: 4100 (nM), Ref: 15115387
TCMC1104	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 1700 (nM), Ref: 25765759 IC50: 60 (nM), Ref: 25765759 IC50: 800 (nM), Ref: 25765759 IC50: 60 (nM), Ref: 25765759 IC50: 3500 (nM), Ref: 25765759
TCMC1104	TCMT679	Macrophage-expressed gene 1 protein	Homo sapiens	IC50: 210 (nM), Ref: 25765759 IC50: 210 (nM), Ref: 25765759
TCMC1104	TCMT680	Histone acetyltransferase PCAF	Homo sapiens	IC50: 7200 (nM), Ref: 26701186
TCMC315	TCMT46	Coagulation factor III	Homo sapiens	IC50: 14.98 (nM), Ref: 23199480
TCMC1396	TCMT689	Protein-glutamine gamma-glutamyltransferase	Homo sapiens	IC50: 8000 (nM), Ref: 21215619
TCMC632	TCMT597	Solute carrier family 28 member 3	Homo sapiens	Ki: 2100 (nM), Ref: 23388705 IC50: 3300 (nM), Ref: 23388705
TCMC632	TCMT709	Sodium/nucleoside cotransporter 2	Homo sapiens	Ki: 5300 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT710	Sodium/nucleoside cotransporter 1	Homo sapiens	Ki: 1800 (nM), Ref: 23388705 IC50: 5500 (nM), Ref: 23388705
TCMC632	TCMT296	Adenosine A1 receptor	Homo sapiens	IC50: 2.344 (nM), Ref: 26756468
TCMC632	TCMT112	Adenosine A3 receptor	Homo sapiens	IC50: 1.148 (nM), Ref: 26756468
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC1446	TCMT83	Lymphocyte differentiation antigen CD38	Homo sapiens	IC50: 6300 (nM), Ref: 21641214
TCMC1102	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 7500 (nM), Ref: 16610779
TCMC1102	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 40 (nM), Ref: 19414254
TCMC1102	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2320 (nM), Ref: 20185318
TCMC1102	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2180 (nM), Ref: 20185318
TCMC1102	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC1102	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 7590 (nM), Ref: 20185318
TCMC1102	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7060 (nM), Ref: 20185318
TCMC1102	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6320 (nM), Ref: 20185318 Ki: 8790 (nM), Ref: 22892213
TCMC1102	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9370 (nM), Ref: 20185318
TCMC1102	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8910 (nM), Ref: 20185318
TCMC1102	TCMT753	Mothers against decapentaplegic homolog 3	Homo sapiens	IC50: 142 (nM), Ref:
TCMC1102	TCMT721	Heat shock 70 kDa protein 1	Homo sapiens	IC50: 760 (nM), Ref:
TCMC1102	TCMT189	Dual specificity protein phosphatase 3	Homo sapiens	IC50: 1230 (nM), Ref: IC50: 980 (nM), Ref:
TCMC1102	TCMT223	Aldose reductase	Homo sapiens	IC50: 200 (nM), Ref: 22261024
TCMC1102	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 3340 (nM), Ref: 22377675
TCMC1102	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 510 (nM), Ref: 22377675
TCMC1102	TCMT354	Serine/threonine-protein kinase Aurora-A	Homo sapiens	IC50: 2480 (nM), Ref: 22377675
TCMC1102	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 2500 (nM), Ref: 22377675
TCMC1102	TCMT626	Serine/threonine-protein kinase B-raf	Homo sapiens	IC50: 1760 (nM), Ref: 22377675
TCMC1102	TCMT423	Epidermal growth factor receptor erbB1	Homo sapiens	IC50: 690 (nM), Ref: 22377675
TCMC1102	TCMT418	Ephrin type-B receptor 4	Homo sapiens	IC50: 1830 (nM), Ref: 22377675
TCMC1102	TCMT704	Receptor protein-tyrosine kinase erbB-2	Homo sapiens	IC50: 3540 (nM), Ref: 22377675
TCMC1102	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 3110 (nM), Ref: 22377675
TCMC1102	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 250 (nM), Ref: 22377675
TCMC1102	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 800 (nM), Ref: 22377675
TCMC1102	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 790 (nM), Ref: 22377675
TCMC1102	TCMT457	Vascular endothelial growth factor receptor 3	Homo sapiens	IC50: 1540 (nM), Ref: 22377675
TCMC1102	TCMT377	Insulin receptor	Homo sapiens	IC50: 340 (nM), Ref: 22377675
TCMC1102	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 22377675
TCMC1102	TCMT536	Platelet-derived growth factor receptor beta	Homo sapiens	IC50: 1300 (nM), Ref: 22377675
TCMC1102	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 3340 (nM), Ref: 22377675
TCMC1102	TCMT755	Serine/threonine-protein kinase PLK4	Homo sapiens	IC50: 2970 (nM), Ref: 22377675
TCMC1102	TCMT502	Tyrosine-protein kinase TIE-2	Homo sapiens	IC50: 260 (nM), Ref: 22377675
TCMC1102	TCMT756	Mitogen-activated protein kinase kinase kinase 8	Homo sapiens	IC50: 2370 (nM), Ref: 22377675
TCMC1102	TCMT739	G-protein coupled receptor 35	Homo sapiens	IC50: 100 (nM), Ref: 24900447
TCMC1102	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8150 (nM), Ref: 22892213
TCMC1102	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 4240 (nM), Ref: 22892213
TCMC1102	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 3900 (nM), Ref: 24835197
TCMC1409	TCMT22	Intestinal alkaline phosphatase	Homo sapiens	IC50: 5250 (nM), Ref: IC50: 8960 (nM), Ref:
TCMC1409	TCMT223	Aldose reductase	Homo sapiens	IC50: 4500 (nM), Ref: 22261024
TCMC1409	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 6211.2 (nM), Ref: 26498393 Ki: 410 (nM), Ref: 26498393
TCMC1409	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 75.7 (nM), Ref: 26498393
TCMC1409	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 3.8 (nM), Ref: 26498393
TCMC1409	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 52.1 (nM), Ref: 26498393 Ki: 170 (nM), Ref: 26498393
TCMC6	TCMT46	Coagulation factor III	Homo sapiens	IC50: 152.43 (nM), Ref: 23199480
TCMC6	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 50 (nM), Ref: 23332346
TCMC6	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 305 (nM), Ref: 23332346
TCMC6	TCMT36	Serotonin 1a (5-HT1a) receptor	Homo sapiens	Ki: 149 (nM), Ref: 23332346
TCMC2053	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 22 (nM), Ref: 23332346
TCMC2053	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 214 (nM), Ref: 23332346
TCMC162	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 1189 (nM), Ref: 23332346
TCMC469	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 100 (nM), Ref: 22921742
TCMC264	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 105 (nM), Ref: 23332346
TCMC264	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 6.6 (nM), Ref: 23332346
TCMC2150	TCMT46	Coagulation factor III	Homo sapiens	IC50: 22.78 (nM), Ref: 23199480
TCMC2150	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 231 (nM), Ref: 23332346
TCMC858	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 66 (nM), Ref: 23332346
TCMC858	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 119 (nM), Ref: 23332346
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC418	TCMT223	Aldose reductase	Homo sapiens	IC50: 78 (nM), Ref: 22236472
TCMC418	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 240 (nM), Ref: 22236472
TCMC418	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 4700 (nM), Ref: 22921742
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC2204	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 482 (nM), Ref: 21067924 Ki: 478 (nM), Ref: 22077347 Ki: 480 (nM), Ref: 26688270
TCMC2204	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 754 (nM), Ref: 22077347 Ki: 750 (nM), Ref: 26688270
TCMC38	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 529 (nM), Ref: 23332346
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC341	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 510 (nM), Ref: 19231207
TCMC1551	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1900 (nM), Ref: 16248836 Ki: 1900 (nM), Ref: 16248836 Ki: 800 (nM), Ref: 16248836 Ki: 250 (nM), Ref: 22696418
TCMC1551	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 760 (nM), Ref: 23746477
TCMC1551	TCMT268	Cytochrome P450 2A13	Homo sapiens	Ki: 40 (nM), Ref: 22696418
TCMC847	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 8710 (nM), Ref: 20185318 Ki: 8710 (nM), Ref: 26498394
TCMC847	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9060 (nM), Ref: 20185318 Ki: 9060 (nM), Ref: 26498394
TCMC847	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7870 (nM), Ref: 20185318
TCMC847	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6420 (nM), Ref: 20185318
TCMC847	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 7330 (nM), Ref: 20185318
TCMC847	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9080 (nM), Ref: 20185318
TCMC847	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6490 (nM), Ref: 20185318
TCMC847	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 10000 (nM), Ref: 20185318
TCMC847	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 1610 (nM), Ref: 20185318
TCMC847	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2380 (nM), Ref: 20185318
TCMC847	TCMT101	Protein-tyrosine phosphatase 1B	Homo sapiens	IC50: 3060 (nM), Ref: 19476336
TCMC847	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 21.22 (nM), Ref: 23375794 IC50: 10 (nM), Ref: 23375794
TCMC847	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 24.26 (nM), Ref: 23375794
TCMC847	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 238.91 (nM), Ref: 23375794
TCMC847	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 8500 (nM), Ref: 26197161
TCMC429	TCMT853	Sigma opioid receptor	Homo sapiens	Ki: 106 (nM), Ref: 27032890
TCMC429	TCMT651	Dopamine D3 receptor	Homo sapiens	Ki: 37 (nM), Ref: 27032890
TCMC429	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 102 (nM), Ref: 27032890
TCMC429	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 15 (nM), Ref: 27032890
TCMC1655	TCMT643	Alpha-1a adrenergic receptor	Homo sapiens	Ki: 430 (nM), Ref: 15664832
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC273	TCMT332	Amine oxidase, copper containing	Homo sapiens	IC50: 4100 (nM), Ref: 23664164
TCMC234	TCMT615	Sentrin-specific protease 8	Homo sapiens	IC50: 5470 (nM), Ref:
TCMC234	TCMT616	Sentrin-specific protease 7	Homo sapiens	IC50: 4630 (nM), Ref:
TCMC234	TCMT617	Sentrin-specific protease 6	Homo sapiens	IC50: 1860 (nM), Ref:
TCMC2146	TCMT46	Coagulation factor III	Homo sapiens	IC50: 8.35 (nM), Ref: 23199480
TCMC1961	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 600 (nM), Ref: 16248836
TCMC1961	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 6480 (nM), Ref: 23746477
TCMC784	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 100 (nM), Ref: 26003344
TCMC784	TCMT132	Butyrylcholinesterase	Homo sapiens	IC50: 1090 (nM), Ref: 26003344
TCMC265	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 91 (nM), Ref: 23332346
TCMC265	TCMT27	Dopamine D1 receptor	Homo sapiens	Ki: 4.5 (nM), Ref: 23332346

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1803	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 2 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC1324	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 41.8 (ug/ml), Ref: 20116898
TCMC469	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 5.4 (ug/ml), Ref: 16643034
TCMC1858	TCMT1112	Quinolone resistance protein norA	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC658	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 49.81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC1957	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1395	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 64 (ug/ml), Ref: 23369537
TCMC2354	TCMT1251	Candida albicans	Candida albicans	IC50: 81.47 (ug/ml), Ref: 25686593
TCMC1803	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 32 (ug/ml), Ref: 23369537
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC2383	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2386	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7 (ug/ml), Ref: 17625894
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1424	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC737	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 26.9 (ug/ml), Ref: 15104496
TCMC737	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 35.8 (ug/ml), Ref: 15104496
TCMC737	TCMT1449	Influenza A virus	Influenza A virus	IC50: 24.5 (ug/ml), Ref: 15104496
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC1748	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 7.15 (ug/ml), Ref: 8786363 IC50: 2.7 (ug/ml), Ref: 8786363
TCMC1104	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 50 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1104	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 35.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 49 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 14.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC2438	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 100 (ug/ml), Ref: 25462220
TCMC2439	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 2 (ug/ml), Ref: 9784148
TCMC1102	TCMT1246	Escherichia coli	Escherichia coli	MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1102	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.103 (ug/ml), Ref: 11374952 IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 0.103 (ug/ml), Ref: 11374952 IC50: 0.145 (ug/ml), Ref: 11374952
TCMC1102	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 5.5 (ug/ml), Ref: 12502337
TCMC1409	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 94 (ug/ml), Ref: 15104489
TCMC1409	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 5.9 (ug/ml), Ref: 15104496
TCMC1409	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 23.4 (ug/ml), Ref: 15104496
TCMC1409	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 12762812
TCMC1409	TCMT1443	Leishmania amazonensis	Leishmania amazonensis	IC50: 0.78 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC2493	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20004575 MIC: 1.56 (ug/ml), Ref: 22280816
TCMC934	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.9 (ug/ml), Ref: 8786363 IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2538	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 9868154
TCMC2538	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 9868154
TCMC2539	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC858	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 0.555 (ug/ml), Ref: 3286870 IC50: 1.739 (ug/ml), Ref: 3286870
TCMC858	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 42.71 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC2561	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 0.67 (ug/ml), Ref: 12193014
TCMC2561	TCMT1438	Plasmodium falciparum	Plasmodium falciparum NF54	IC50: 0.91 (ug/ml), Ref: 12193014
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC924	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 64 (ug/ml), Ref: 24641242
TCMC915	TCMT1246	Escherichia coli	Escherichia coli	MIC: 1 (ug/ml), Ref: 25791674
TCMC915	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2182	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC2166	TCMT1211	Fusobacterium nucleatum	Fusobacterium nucleatum	MIC: 50 (ug/ml), Ref: 8864235
TCMC2166	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1321	Staphylococcus hominis	Staphylococcus hominis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906 MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1209	Staphylococcus haemolyticus	Staphylococcus haemolyticus	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1343	Staphylococcus simulans	Staphylococcus simulans	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1344	Staphylococcus sciuri	Staphylococcus sciuri	MIC: 32 (ug/ml), Ref: 19651906 MIC50: 64 (ug/ml), Ref: 19651906 MBC: 64 (ug/ml), Ref: 19651906 MIC: 4 (ug/ml), Ref: 19651906 MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166	TCMT1251	Candida albicans	Candida albicans	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1246	Escherichia coli	Escherichia coli	MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC348	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 62 (ug/ml), Ref: 25813159
TCMC2615	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 3.5 (ug/ml), Ref: 25316317
TCMC2615	TCMT1222	Plasmodium falciparum D6	Plasmodium falciparum D6	IC50: 4.2 (ug/ml), Ref: 25316317 IC50: 1.95 (ug/ml), Ref: 25316317
TCMC2615	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 1 (ug/ml), Ref: 25316317
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC946	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 14510592
TCMC912	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1551	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 20832915
TCMC1578	TCMT1408	Colletotrichum gloeosporioides	Colletotrichum gloeosporioides	IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578	TCMT1245	Phytophthora cactorum	Phytophthora cactorum	IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1776	TCMT1253	Penicillium chrysogenum	Penicillium chrysogenum	MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1961	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 6.25 (ug/ml), Ref: 20832915
TCMC784	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2822	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 6.25 (ug/ml), Ref: 17845001