TCM Putative Target References: TCMFx1608


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC172
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 310 (nM), Ref: 23332346
TCMC658
TCMT34 Cytochrome P450 2D6 Homo sapiens Ki: 122 (nM), Ref: 26125082
TCMC1957
TCMT34 Cytochrome P450 2D6 Homo sapiens Ki: 78 (nM), Ref: 26125082
TCMC1258
TCMT37 Serotonin 2a (5-HT2a) receptor Homo sapiens Ki: 966 (nM), Ref: 25695425
TCMC1258
TCMT160 Serotonin 7 (5-HT7) receptor Homo sapiens Ki: 43 (nM), Ref: 25695425
TCMC1258
TCMT36 Serotonin 1a (5-HT1a) receptor Homo sapiens Ki: 171 (nM), Ref: 25695425
TCMC1424
TCMT33 Cytochrome P450 3A4 Homo sapiens IC50: 2100 (nM), Ref: 17994701
TCMC1748
TCMT36 Serotonin 1a (5-HT1a) receptor Homo sapiens Ki: 85 (nM), Ref: 16562853
Ki: 314 (nM), Ref: 25695425
TCMC1748
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 373 (nM), Ref: 25695425
TCMC1748
TCMT160 Serotonin 7 (5-HT7) receptor Homo sapiens Ki: 20 (nM), Ref: 25695425
TCMC1748
TCMT315 Serotonin 6 (5-HT6) receptor Homo sapiens Ki: 306 (nM), Ref: 25695425
TCMC1748
TCMT646 Serotonin 5a (5-HT5a) receptor Homo sapiens Ki: 566 (nM), Ref: 25695425
TCMC1748
TCMT313 Serotonin 2b (5-HT2b) receptor Homo sapiens Ki: 323 (nM), Ref: 25695425
TCMC315
TCMT46 Coagulation factor III Homo sapiens IC50: 14.98 (nM), Ref: 23199480
TCMC632
TCMT597 Solute carrier family 28 member 3 Homo sapiens Ki: 2100 (nM), Ref: 23388705
IC50: 3300 (nM), Ref: 23388705
TCMC632
TCMT709 Sodium/nucleoside cotransporter 2 Homo sapiens Ki: 5300 (nM), Ref: 23388705
IC50: 5500 (nM), Ref: 23388705
TCMC632
TCMT710 Sodium/nucleoside cotransporter 1 Homo sapiens Ki: 1800 (nM), Ref: 23388705
IC50: 5500 (nM), Ref: 23388705
TCMC632
TCMT296 Adenosine A1 receptor Homo sapiens IC50: 2.344 (nM), Ref: 26756468
TCMC632
TCMT112 Adenosine A3 receptor Homo sapiens IC50: 1.148 (nM), Ref: 26756468
TCMC6
TCMT46 Coagulation factor III Homo sapiens IC50: 152.43 (nM), Ref: 23199480
TCMC6
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 50 (nM), Ref: 23332346
TCMC6
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 305 (nM), Ref: 23332346
TCMC6
TCMT36 Serotonin 1a (5-HT1a) receptor Homo sapiens Ki: 149 (nM), Ref: 23332346
TCMC2053
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 22 (nM), Ref: 23332346
TCMC2053
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 214 (nM), Ref: 23332346
TCMC162
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 1189 (nM), Ref: 23332346
TCMC264
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 105 (nM), Ref: 23332346
TCMC264
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 6.6 (nM), Ref: 23332346
TCMC2150
TCMT46 Coagulation factor III Homo sapiens IC50: 22.78 (nM), Ref: 23199480
TCMC2150
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 231 (nM), Ref: 23332346
TCMC858
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 66 (nM), Ref: 23332346
TCMC858
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 119 (nM), Ref: 23332346
TCMC38
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 529 (nM), Ref: 23332346
TCMC429
TCMT853 Sigma opioid receptor Homo sapiens Ki: 106 (nM), Ref: 27032890
TCMC429
TCMT651 Dopamine D3 receptor Homo sapiens Ki: 37 (nM), Ref: 27032890
TCMC429
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 102 (nM), Ref: 27032890
TCMC429
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 15 (nM), Ref: 27032890
TCMC1655
TCMT643 Alpha-1a adrenergic receptor Homo sapiens Ki: 430 (nM), Ref: 15664832
TCMC234
TCMT615 Sentrin-specific protease 8 Homo sapiens IC50: 5470 (nM), Ref:
TCMC234
TCMT616 Sentrin-specific protease 7 Homo sapiens IC50: 4630 (nM), Ref:
TCMC234
TCMT617 Sentrin-specific protease 6 Homo sapiens IC50: 1860 (nM), Ref:
TCMC2146
TCMT46 Coagulation factor III Homo sapiens IC50: 8.35 (nM), Ref: 23199480
TCMC784
TCMT131 Acetylcholinesterase Homo sapiens IC50: 100 (nM), Ref: 26003344
TCMC784
TCMT132 Butyrylcholinesterase Homo sapiens IC50: 1090 (nM), Ref: 26003344
TCMC265
TCMT38 Dopamine D2 receptor Homo sapiens Ki: 91 (nM), Ref: 23332346
TCMC265
TCMT27 Dopamine D1 receptor Homo sapiens Ki: 4.5 (nM), Ref: 23332346

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC658
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 49.81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1957
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2383
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 37.96 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1424
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 27.95 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1748
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 7.15 (ug/ml), Ref: 8786363
IC50: 2.7 (ug/ml), Ref: 8786363
TCMC1748
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 7.15 (ug/ml), Ref: 8786363
IC50: 2.7 (ug/ml), Ref: 8786363
TCMC934
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 52.73 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1387
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 1.9 (ug/ml), Ref: 8786363
IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 1.9 (ug/ml), Ref: 8786363
IC50: 2.83 (ug/ml), Ref: 8786363
TCMC1387
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 50.13 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC858
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 0.555 (ug/ml), Ref: 3286870
IC50: 1.739 (ug/ml), Ref: 3286870
TCMC858
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 42.71 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC784
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 1 (ug/ml), Ref: 10.1007/s00044-011-9767-1