TCM Putative Target References: TCMFx891


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1173
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9430 (nM), Ref: 20185318
Ki: 9430 (nM), Ref: 26498394
TCMC1173
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9780 (nM), Ref: 20185318
Ki: 9780 (nM), Ref: 26498394
TCMC1173
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9870 (nM), Ref: 20185318
TCMC1173
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7410 (nM), Ref: 20185318
TCMC1173
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 8450 (nM), Ref: 20185318
TCMC1173
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 7040 (nM), Ref: 20185318
TCMC1173
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2400 (nM), Ref: 20185318
TCMC1173
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2890 (nM), Ref: 20185318
TCMC1495
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 1000 (nM), Ref: 20471252
IC50: 1000 (nM), Ref: 25461324
IC50: 1000 (nM), Ref: 25461324
Ki: 9300 (nM), Ref: 27460668
TCMC1495
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 1000 (nM), Ref: 20471252
Ki: 6800 (nM), Ref: 27460668
TCMC1495
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1956
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 1080 (nM), Ref: 21282059
TCMC1956
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 470 (nM), Ref: 21282059
TCMC1956
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 4450 (nM), Ref: 21282059
TCMC1956
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4090 (nM), Ref: 21282059
TCMC1956
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 4720 (nM), Ref: 21669522
Ki: 4720 (nM), Ref: 22687439
TCMC1956
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 2450 (nM), Ref: 22687439
TCMC1956
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 690 (nM), Ref: 22668600
TCMC1956
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7870 (nM), Ref: 22668600
TCMC1830
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 930 (nM), Ref: 15357969
TCMC1830
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 2600 (nM), Ref: 15357969
TCMC1830
TCMT808 Fatty acid binding protein epidermal Homo sapiens IC50: 1200 (nM), Ref: 15357969
TCMC1830
TCMT809 Fatty acid binding protein intestinal Homo sapiens IC50: 1700 (nM), Ref: 15357969
TCMC1830
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1830
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC846
TCMT207 Beta-secretase 1 Homo sapiens Ki: 6200 (nM), Ref: 22222157
TCMC1788
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT126 Telomerase reverse transcriptase Homo sapiens IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788
TCMT297 Fatty acid binding protein adipocyte Homo sapiens Ki: 1500 (nM), Ref: 27460668
TCMC341
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 510 (nM), Ref: 19231207
TCMC847
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 8710 (nM), Ref: 20185318
Ki: 8710 (nM), Ref: 26498394
TCMC847
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9060 (nM), Ref: 20185318
Ki: 9060 (nM), Ref: 26498394
TCMC847
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 7870 (nM), Ref: 20185318
TCMC847
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6420 (nM), Ref: 20185318
TCMC847
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 7330 (nM), Ref: 20185318
TCMC847
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 9080 (nM), Ref: 20185318
TCMC847
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 6490 (nM), Ref: 20185318
TCMC847
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 10000 (nM), Ref: 20185318
TCMC847
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 1610 (nM), Ref: 20185318
TCMC847
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2380 (nM), Ref: 20185318
TCMC847
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 3060 (nM), Ref: 19476336
TCMC847
TCMT321 Matrix metalloproteinase 9 Homo sapiens IC50: 21.22 (nM), Ref: 23375794
IC50: 10 (nM), Ref: 23375794
TCMC847
TCMT306 Matrix metalloproteinase-2 Homo sapiens IC50: 24.26 (nM), Ref: 23375794
TCMC847
TCMT295 Matrix metalloproteinase-1 Homo sapiens IC50: 238.91 (nM), Ref: 23375794
TCMC847
TCMT130 Arachidonate 5-lipoxygenase Homo sapiens IC50: 8500 (nM), Ref: 26197161
TCMC897
TCMT223 Aldose reductase Homo sapiens IC50: 300 (nM), Ref: 22236472
IC50: 1800 (nM), Ref: 22261024
TCMC897
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens IC50: 7900 (nM), Ref: 22236472
TCMC273
TCMT332 Amine oxidase, copper containing Homo sapiens IC50: 4100 (nM), Ref: 23664164

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1866
TCMT1112 Quinolone resistance protein norA Staphylococcus aureus MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC2354
TCMT1251 Candida albicans Candida albicans IC50: 81.47 (ug/ml), Ref: 25686593
TCMC2539
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC1830
TCMT1361 Neisseria meningitidis Neisseria meningitidis MIC: 50 (ug/ml), Ref: 19884363
TCMC1830
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 3.8 (ug/ml), Ref: 20855214
IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830
TCMT1442 Leishmania donovani Leishmania donovani IC50: 14.5 (ug/ml), Ref: 20855214
TCMC924
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 64 (ug/ml), Ref: 24641242
TCMC2166
TCMT1211 Fusobacterium nucleatum Fusobacterium nucleatum MIC: 50 (ug/ml), Ref: 8864235
TCMC2166
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1321 Staphylococcus hominis Staphylococcus hominis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1209 Staphylococcus haemolyticus Staphylococcus haemolyticus MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1343 Staphylococcus simulans Staphylococcus simulans MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1344 Staphylococcus sciuri Staphylococcus sciuri MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1251 Candida albicans Candida albicans MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1246 Escherichia coli Escherichia coli MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC1788
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 24103427
TCMC912
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1578
TCMT1408 Colletotrichum gloeosporioides Colletotrichum gloeosporioides IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578
TCMT1245 Phytophthora cactorum Phytophthora cactorum IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1776
TCMT1253 Penicillium chrysogenum Penicillium chrysogenum MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC897
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 6.25 (ug/ml), Ref: 12762812
TCMC2822
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 6.25 (ug/ml), Ref: 17845001