TCM Putative Target References: TCMFx799


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.
Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1173
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9430 (nM), Ref: 20185318
Ki: 9430 (nM), Ref: 26498394
TCMC1173
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9780 (nM), Ref: 20185318
Ki: 9780 (nM), Ref: 26498394
TCMC1173
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9870 (nM), Ref: 20185318
TCMC1173
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7410 (nM), Ref: 20185318
TCMC1173
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 8450 (nM), Ref: 20185318
TCMC1173
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 7040 (nM), Ref: 20185318
TCMC1173
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 2400 (nM), Ref: 20185318
TCMC1173
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2890 (nM), Ref: 20185318
TCMC943
TCMT174 11-beta-hydroxysteroid dehydrogenase 1 Homo sapiens IC50: 810 (nM), Ref: 20100662
TCMC943
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 7000 (nM), Ref: 22940448
IC50: 5490 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 5490 (nM), Ref: 10.1007/s00044-010-9529-5
TCMC61
TCMT193 Nuclear factor NF-kappa-B p65 subunit Homo sapiens IC50: 250 (nM), Ref: 21513293
TCMC61
TCMT194 Mitogen-activated protein kinase kinase kinase 7 Homo sapiens IC50: 80 (nM), Ref: 25529738
IC50: 11 (nM), Ref: 26481152
IC50: 8.1 (nM), Ref: 26481152
IC50: 9 (nM), Ref: 27448772
TCMC61
TCMT80 MAP kinase ERK2 Homo sapiens IC50: 6800 (nM), Ref: 25529738
TCMC61
TCMT195 Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens IC50: 80 (nM), Ref: 25529738
TCMC61
TCMT196 Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens IC50: 1300 (nM), Ref: 25529738
TCMC2051
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 8710 (nM), Ref: 22892213
TCMC2051
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4050 (nM), Ref: 22892213
TCMC2051
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 960 (nM), Ref: 22892213
TCMC1107
TCMT290 Muscarinic acetylcholine receptor M5 Homo sapiens Ki: 0.14 (nM), Ref: 23707254
Ki: 0.3388 (nM), Ref: 24365159
Ki: 0.34 (nM), Ref: 24365159
Ki: 3.02 (nM), Ref: 25051097
TCMC1107
TCMT291 Muscarinic acetylcholine receptor M3 Homo sapiens Ki: 0.2692 (nM), Ref: 24365159
Ki: 0.27 (nM), Ref: 24365159
TCMC1107
TCMT292 Muscarinic acetylcholine receptor M1 Homo sapiens Ki: 0.2692 (nM), Ref: 24365159
Ki: 0.27 (nM), Ref: 24365159
TCMC1107
TCMT293 Muscarinic acetylcholine receptor M2 Homo sapiens Ki: 5.012 (nM), Ref: 25051097
Ki: 12.88 (nM), Ref: 25051097
Ki: 3.631 (nM), Ref: 25051097
Ki: 2.818 (nM), Ref: 25051097
TCMC1495
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 1000 (nM), Ref: 20471252
IC50: 1000 (nM), Ref: 25461324
IC50: 1000 (nM), Ref: 25461324
Ki: 9300 (nM), Ref: 27460668
TCMC1495
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 1000 (nM), Ref: 20471252
Ki: 6800 (nM), Ref: 27460668
TCMC1495
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC824
TCMT301 Prostaglandin E synthase Homo sapiens IC50: 5000 (nM), Ref: 24844534
TCMC962
TCMT45 Beta amyloid A4 protein Homo sapiens Ki: 0.208 (nM), Ref: 17004725
IC50: 800 (nM), Ref: 17270435
IC50: 3900 (nM), Ref: 26099993
TCMC962
TCMT566 Nitric oxide synthase, inducible Homo sapiens IC50: 6000 (nM), Ref: 18077363
TCMC962
TCMT87 Cytochrome P450 2C9 Homo sapiens IC50: 4300 (nM), Ref: 18249473
TCMC962
TCMT321 Matrix metalloproteinase 9 Homo sapiens IC50: 8500 (nM), Ref: 19128977
TCMC962
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2410 (nM), Ref: 20674354
TCMC962
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 380 (nM), Ref: 20674354
TCMC962
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 4970 (nM), Ref: 20674354
TCMC962
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 9460 (nM), Ref: 20674354
TCMC962
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 9940 (nM), Ref: 20674354
TCMC962
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 9300 (nM), Ref: 20674354
TCMC962
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 4050 (nM), Ref: 20674354
TCMC962
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 3480 (nM), Ref: 20674354
TCMC962
TCMT225 Carbonic anhydrase XIII Homo sapiens Ki: 6850 (nM), Ref: 20674354
TCMC962
TCMT44 Glyoxalase I Homo sapiens Ki: 10000 (nM), Ref: 21237663
TCMC962
TCMT22 Intestinal alkaline phosphatase Homo sapiens IC50: 7410 (nM), Ref:
TCMC962
TCMT46 Coagulation factor III Homo sapiens IC50: 199.63 (nM), Ref: 10.1007/s00044-012-0330-5
IC50: 199.63 (nM), Ref: 23199480
TCMC962
TCMT423 Epidermal growth factor receptor erbB1 Homo sapiens IC50: 8600 (nM), Ref: 23245570
TCMC962
TCMT174 11-beta-hydroxysteroid dehydrogenase 1 Homo sapiens IC50: 4501 (nM), Ref: 23800686
TCMC962
TCMT570 Aminopeptidase N Homo sapiens IC50: 10000 (nM), Ref: 23860593
TCMC962
TCMT130 Arachidonate 5-lipoxygenase Homo sapiens IC50: 3900 (nM), Ref: 24920381
IC50: 500 (nM), Ref: 24920381
IC50: 600 (nM), Ref: 24920381
IC50: 600 (nM), Ref: 24920381
IC50: 600 (nM), Ref: 24920381
TCMC962
TCMT164 Cyclooxygenase-1 Homo sapiens IC50: 8100 (nM), Ref: 24920381
TCMC962
TCMT301 Prostaglandin E synthase Homo sapiens IC50: 600 (nM), Ref: 24920381
IC50: 1200 (nM), Ref: 24920381
TCMC962
TCMT3 Arachidonate 15-lipoxygenase Homo sapiens IC50: 1200 (nM), Ref: 24920381
TCMC962
TCMT207 Beta-secretase 1 Homo sapiens IC50: 5300 (nM), Ref: 25088549
TCMC962
TCMT565 Histone acetyltransferase p300 Homo sapiens IC50: 6500 (nM), Ref: 25730130
TCMC42
TCMT265 Glycogen synthase kinase-3 beta Homo sapiens IC50: 8390 (nM), Ref: 26696252
TCMC42
TCMT207 Beta-secretase 1 Homo sapiens IC50: 2540 (nM), Ref: 26696252
TCMC694
TCMT230 Estradiol 17-beta-dehydrogenase 3 Homo sapiens IC50: 758 (nM), Ref: 11086723
IC50: 758 (nM), Ref: 16078844
TCMC694
TCMT156 Cytochrome P450 19A1 Homo sapiens Ki: 20 (nM), Ref: 8035427
Ki: 35 (nM), Ref: 26469743
TCMC949
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 8900 (nM), Ref: 19911821
TCMC949
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 48 (nM), Ref: 19911821
TCMC949
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9100 (nM), Ref: 19911821
TCMC949
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 3300 (nM), Ref: 19911821
TCMC949
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 2000 (nM), Ref: 19911821
TCMC949
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 5200 (nM), Ref: 19911821
TCMC949
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 9400 (nM), Ref: 19911821
TCMC949
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 6800 (nM), Ref: 19911821
TCMC949
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 5600 (nM), Ref: 19911821
TCMC949
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 3100 (nM), Ref: 19911821
Ki: 3100 (nM), Ref: 21067924
Ki: 3100 (nM), Ref: 22137345
Ki: 3100 (nM), Ref: 22077347
Ki: 3100 (nM), Ref: 22365761
Ki: 3100 (nM), Ref: 22377674
Ki: 3100 (nM), Ref: 23241068
Ki: 3100 (nM), Ref: 22892213
Ki: 3100 (nM), Ref: 26688270
TCMC949
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 9200 (nM), Ref: 21067924
Ki: 9200 (nM), Ref: 22137345
Ki: 9200 (nM), Ref: 22077347
Ki: 9200 (nM), Ref: 22365761
Ki: 9200 (nM), Ref: 22377674
Ki: 9200 (nM), Ref: 23241068
Ki: 9200 (nM), Ref: 22892213
Ki: 9200 (nM), Ref: 26688270
TCMC498
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 410 (nM), Ref: 26688270
TCMC498
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 6300 (nM), Ref: 26688270
TCMC262
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 8040 (nM), Ref: 10.1007/s00044-010-9529-5
IC50: 8040 (nM), Ref: 10.1007/s00044-010-9529-5
TCMC262
TCMT301 Prostaglandin E synthase Homo sapiens IC50: 3000 (nM), Ref: 24844534
TCMC1956
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 1080 (nM), Ref: 21282059
TCMC1956
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 470 (nM), Ref: 21282059
TCMC1956
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 4450 (nM), Ref: 21282059
TCMC1956
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 4090 (nM), Ref: 21282059
TCMC1956
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 4720 (nM), Ref: 21669522
Ki: 4720 (nM), Ref: 22687439
TCMC1956
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 2450 (nM), Ref: 22687439
TCMC1956
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 690 (nM), Ref: 22668600
TCMC1956
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 7870 (nM), Ref: 22668600
TCMC1113
TCMT47 Apoptosis regulator Bcl-2 Homo sapiens Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC43
TCMT301 Prostaglandin E synthase Homo sapiens IC50: 220 (nM), Ref: 26588603
IC50: 200 (nM), Ref: 10.1039/C5MD00278H
TCMC43
TCMT565 Histone acetyltransferase p300 Homo sapiens IC50: 6500 (nM), Ref: 26701186
TCMC43
TCMT208 Monoamine oxidase A Homo sapiens Ki: 710 (nM), Ref: 26819666
TCMC43
TCMT45 Beta amyloid A4 protein Homo sapiens IC50: 3100 (nM), Ref: 27190601
IC50: 1500 (nM), Ref: 27190601
TCMC2142
TCMT156 Cytochrome P450 19A1 Homo sapiens Ki: 600 (nM), Ref: 6827528
TCMC2142
TCMT33 Cytochrome P450 3A4 Homo sapiens IC50: 10000 (nM), Ref: 14552748
TCMC2142
TCMT187 Androgen Receptor Homo sapiens IC50: 3.9 (nM), Ref: 15456242
IC50: 2.7 (nM), Ref: 16309907
IC50: 4.571 (nM), Ref: 22746350
IC50: 4.17 (nM), Ref: 25646649
IC50: 4.27 (nM), Ref: 25646649
TCMC2142
TCMT99 Testis-specific androgen-binding protein Homo sapiens IC50: 14 (nM), Ref: 17149875
TCMC2142
TCMT725 Voltage-gated L-type calcium channel alpha-1C subunit Homo sapiens IC50: 34 (nM), Ref: 22761000
IC50: 38.4 (nM), Ref: 22761000
TCMC916
TCMT161 Hydroxycarboxylic acid receptor 2 Homo sapiens Ki: 4900 (nM), Ref: 21167710
TCMC124
TCMT194 Mitogen-activated protein kinase kinase kinase 7 Homo sapiens IC50: 1300 (nM), Ref: 26481152
TCMC1830
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 930 (nM), Ref: 15357969
TCMC1830
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 2600 (nM), Ref: 15357969
TCMC1830
TCMT808 Fatty acid binding protein epidermal Homo sapiens IC50: 1200 (nM), Ref: 15357969
TCMC1830
TCMT809 Fatty acid binding protein intestinal Homo sapiens IC50: 1700 (nM), Ref: 15357969
TCMC1830
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1830
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC606
TCMT219 Cytochrome P450 1A2 Homo sapiens IC50: 251 (nM), Ref: 20696580
TCMC606
TCMT215 Cytochrome P450 1A1 Homo sapiens IC50: 86 (nM), Ref: 20696580
TCMC606
TCMT257 Cytochrome P450 1B1 Homo sapiens IC50: 12 (nM), Ref: 20696580
TCMC435
TCMT301 Prostaglandin E synthase Homo sapiens IC50: 1100 (nM), Ref: 24844534
TCMC1774
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 3100 (nM), Ref: 20674354
Ki: 3100 (nM), Ref: 21282059
Ki: 3400 (nM), Ref: 22137345
TCMC1774
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 9200 (nM), Ref: 20674354
Ki: 9200 (nM), Ref: 21282059
Ki: 9300 (nM), Ref: 22137345
TCMC2204
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 482 (nM), Ref: 21067924
Ki: 478 (nM), Ref: 22077347
Ki: 480 (nM), Ref: 26688270
TCMC2204
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 754 (nM), Ref: 22077347
Ki: 750 (nM), Ref: 26688270
TCMC2245
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 9180 (nM), Ref: 22892213
TCMC2245
TCMT225 Carbonic anhydrase XIII Homo sapiens Ki: 8360 (nM), Ref: 22892213
TCMC2245
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 7510 (nM), Ref: 22892213
TCMC1788
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7
IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT67 Peroxisome proliferator-activated receptor gamma Homo sapiens IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788
TCMT126 Telomerase reverse transcriptase Homo sapiens IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788
TCMT297 Fatty acid binding protein adipocyte Homo sapiens Ki: 1500 (nM), Ref: 27460668
TCMC1319
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9700 (nM), Ref: 19911821
TCMC1319
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 9000 (nM), Ref: 19911821
TCMC1319
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9800 (nM), Ref: 19911821
TCMC1319
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 2400 (nM), Ref: 19911821
TCMC1319
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 5500 (nM), Ref: 19911821
TCMC1319
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 5100 (nM), Ref: 19911821
TCMC1319
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 8300 (nM), Ref: 19911821
TCMC1319
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 5900 (nM), Ref: 19911821
TCMC341
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 510 (nM), Ref: 19231207
TCMC1551
TCMT206 Cytochrome P450 2A6 Homo sapiens Ki: 1900 (nM), Ref: 16248836
Ki: 1900 (nM), Ref: 16248836
Ki: 800 (nM), Ref: 16248836
Ki: 250 (nM), Ref: 22696418
TCMC1551
TCMT131 Acetylcholinesterase Homo sapiens IC50: 760 (nM), Ref: 23746477
TCMC1551
TCMT268 Cytochrome P450 2A13 Homo sapiens Ki: 40 (nM), Ref: 22696418
TCMC847
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 8710 (nM), Ref: 20185318
Ki: 8710 (nM), Ref: 26498394
TCMC847
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 9060 (nM), Ref: 20185318
Ki: 9060 (nM), Ref: 26498394
TCMC847
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 7870 (nM), Ref: 20185318
TCMC847
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6420 (nM), Ref: 20185318
TCMC847
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 7330 (nM), Ref: 20185318
TCMC847
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 9080 (nM), Ref: 20185318
TCMC847
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 6490 (nM), Ref: 20185318
TCMC847
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 10000 (nM), Ref: 20185318
TCMC847
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 1610 (nM), Ref: 20185318
TCMC847
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 2380 (nM), Ref: 20185318
TCMC847
TCMT101 Protein-tyrosine phosphatase 1B Homo sapiens IC50: 3060 (nM), Ref: 19476336
TCMC847
TCMT321 Matrix metalloproteinase 9 Homo sapiens IC50: 21.22 (nM), Ref: 23375794
IC50: 10 (nM), Ref: 23375794
TCMC847
TCMT306 Matrix metalloproteinase-2 Homo sapiens IC50: 24.26 (nM), Ref: 23375794
TCMC847
TCMT295 Matrix metalloproteinase-1 Homo sapiens IC50: 238.91 (nM), Ref: 23375794
TCMC847
TCMT130 Arachidonate 5-lipoxygenase Homo sapiens IC50: 8500 (nM), Ref: 26197161
TCMC1999
TCMT34 Cytochrome P450 2D6 Homo sapiens Ki: 3.3 (nM), Ref: 8487254
Ki: 4.6 (nM), Ref: 8487254
Ki: 14 (nM), Ref: 8487254
Ki: 5.7 (nM), Ref: 8487254
Ki: 3.5 (nM), Ref: 8487254
Ki: 13 (nM), Ref: 8487254
Ki: 4.6 (nM), Ref: 8487254
TCMC897
TCMT223 Aldose reductase Homo sapiens IC50: 300 (nM), Ref: 22236472
IC50: 1800 (nM), Ref: 22261024
TCMC897
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens IC50: 7900 (nM), Ref: 22236472
TCMC1940
TCMT187 Androgen Receptor Homo sapiens Ki: 8.5 (nM), Ref: 12954062
IC50: 37 (nM), Ref: 12954062
IC50: 37 (nM), Ref: 12781197
IC50: 37 (nM), Ref: 8627601
Ki: 8.5 (nM), Ref: 8627601
Ki: 8.5 (nM), Ref: 9873735
IC50: 37 (nM), Ref: 9784110
Ki: 35 (nM), Ref: 20510622
TCMC1940
TCMT613 Glucocorticoid receptor Homo sapiens Ki: 30.5 (nM), Ref: 12954062
Ki: 30.5 (nM), Ref: 9873735
Ki: 30.5 (nM), Ref: 9784110
TCMC1940
TCMT783 Mineralocorticoid receptor Homo sapiens IC50: 14 (nM), Ref: 12954062
IC50: 14 (nM), Ref: 12781197
IC50: 14 (nM), Ref: 9784110
IC50: 30 (nM), Ref: 8709117
TCMC1940
TCMT904 Progesterone receptor Homo sapiens Ki: 3.5 (nM), Ref: 10212133
IC50: 3.5 (nM), Ref: 11859003
Ki: 3.5 (nM), Ref: 9464361
IC50: 5 (nM), Ref: 8523399
Ki: 3.8 (nM), Ref: 9667968
Ki: 3.467 (nM), Ref: 16821785
Ki: 3.4 (nM), Ref: 18553958
Ki: 5.1 (nM), Ref: 20510622
TCMC273
TCMT332 Amine oxidase, copper containing Homo sapiens IC50: 4100 (nM), Ref: 23664164
TCMC710
TCMT249 Cyclin-dependent kinase 6 Homo sapiens IC50: 1700 (nM), Ref: 15689157
IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC710
TCMT156 Cytochrome P450 19A1 Homo sapiens IC50: 10000 (nM), Ref: 18192087
IC50: 900 (nM), Ref: 20413308
IC50: 1200 (nM), Ref: 26301554
TCMC710
TCMT65 Estradiol 17-beta-dehydrogenase 1 Homo sapiens IC50: 710 (nM), Ref: 18533708
TCMC710
TCMT752 Casein kinase II alpha Homo sapiens IC50: 800 (nM), Ref: 19414254
TCMC710
TCMT187 Androgen Receptor Homo sapiens IC50: 5200 (nM), Ref: 19592245
TCMC710
TCMT219 Cytochrome P450 1A2 Homo sapiens IC50: 795 (nM), Ref: 20696580
TCMC710
TCMT215 Cytochrome P450 1A1 Homo sapiens IC50: 427 (nM), Ref: 20696580
TCMC710
TCMT257 Cytochrome P450 1B1 Homo sapiens IC50: 25 (nM), Ref: 20696580
TCMC710
TCMT265 Glycogen synthase kinase-3 beta Homo sapiens IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710
TCMT131 Acetylcholinesterase Homo sapiens IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710
TCMT260 Tyrosine-protein kinase receptor FLT3 Homo sapiens IC50: 1450 (nM), Ref: 23411073
TCMC710
TCMT128 Tankyrase-2 Homo sapiens IC50: 2951.21 (nM), Ref: 23574272
IC50: 2900 (nM), Ref: 23574272
TCMC710
TCMT129 Tankyrase-1 Homo sapiens IC50: 3162.28 (nM), Ref: 23574272
IC50: 3100 (nM), Ref: 23574272
TCMC710
TCMT592 Xanthine dehydrogenase Homo sapiens Ki: 520 (nM), Ref: 25019478
IC50: 3200 (nM), Ref: 26022844
TCMC710
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens Ki: 6000 (nM), Ref: 26529431
IC50: 6600 (nM), Ref: 26529431
TCMC1961
TCMT206 Cytochrome P450 2A6 Homo sapiens Ki: 600 (nM), Ref: 16248836
TCMC1961
TCMT131 Acetylcholinesterase Homo sapiens IC50: 6480 (nM), Ref: 23746477
TCMC998
TCMT154 Protein kinase C delta Homo sapiens Ki: 9.7 (nM), Ref: 23582444

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC962
TCMT1104 Sortase Staphylococcus aureus IC50: 13.8 (ug/ml), Ref: 19269184
TCMC962
TCMT1108 Integrase Human immunodeficiency virus 1 IC50: 51.3 (ug/ml), Ref: 16643034
TCMC962
TCMT1112 Quinolone resistance protein norA Staphylococcus aureus MIC: 1 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC1206
TCMT1099 Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50: 21.25 (ug/ml), Ref: 20116898
TCMC1514
TCMT1109 Reverse transcriptase Human immunodeficiency virus 1 IC50: 2.1 (ug/ml), Ref: 19515569
TCMC710
TCMT1099 Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50: 8.54 (ug/ml), Ref: 20116898
TCMC943
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 8 (ug/ml), Ref: 9748372
TCMC943
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 32 (ug/ml), Ref: 21288041
MIC: 7 (ug/ml), Ref: 25794790
TCMC943
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 32 (ug/ml), Ref: 21288041
TCMC2324
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC2051
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 42 (ug/ml), Ref: 22280816
MIC: 42.1 (ug/ml), Ref: 26112067
TCMC1395
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 64 (ug/ml), Ref: 23369537
TCMC2354
TCMT1251 Candida albicans Candida albicans IC50: 81.47 (ug/ml), Ref: 25686593
TCMC962
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 4.2 (ug/ml), Ref: 19299148
IC50: 3.5 (ug/ml), Ref: 19299148
TCMC962
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 4.2 (ug/ml), Ref: 19299148
IC50: 3.5 (ug/ml), Ref: 19299148
TCMC962
TCMT1181 Mycobacterium tuberculosis H37Ra Mycobacterium tuberculosis H37Ra MIC: 100 (ug/ml), Ref: 20691508
TCMC962
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 5 (ug/ml), Ref: 19204190
MIC: 15 (ug/ml), Ref: 19204190
MIC: 50 (ug/ml), Ref: 19204190
MIC: 30 (ug/ml), Ref: 19204190
TCMC962
TCMT1215 Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 MIC: 30 (ug/ml), Ref: 18284200
TCMC962
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 16 (ug/ml), Ref: 25938986
MIC: 32 (ug/ml), Ref: 25938986
TCMC1210
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 30 (ug/ml), Ref: 18564877
TCMC2439
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 2 (ug/ml), Ref: 9784148
TCMC2442
TCMT1251 Candida albicans Candida albicans MIC: 50 (ug/ml), Ref: 10924184
TCMC2442
TCMT1439 Mycobacterium smegmatis Mycobacterium smegmatis MIC: 50 (ug/ml), Ref: 10924184
TCMC2442
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 50 (ug/ml), Ref: 10924184
TCMC2442
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 50 (ug/ml), Ref: 10924184
TCMC2444
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 5.8 (ug/ml), Ref: 8786363
IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 5.8 (ug/ml), Ref: 8786363
IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 32 (ug/ml), Ref: 25372601
TCMC2454
TCMT1175 Human immunodeficiency virus Human immunodeficiency virus IC50: 19.6 (ug/ml), Ref: 10425115
TCMC1113
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 0.5 (ug/ml), Ref: 15863332
TCMC1206
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 44.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1515
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 20542692
TCMC2539
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC1830
TCMT1361 Neisseria meningitidis Neisseria meningitidis MIC: 50 (ug/ml), Ref: 19884363
TCMC1830
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 3.8 (ug/ml), Ref: 20855214
IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830
TCMT1442 Leishmania donovani Leishmania donovani IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2550
TCMT1393 Vibrio sp. Vibrio sp. MIC: 15 (ug/ml), Ref: 21865038
TCMC2566
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 50 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC924
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 64 (ug/ml), Ref: 24641242
TCMC2571
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 13.4 (ug/ml), Ref: 15104489
TCMC606
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 5.5 (ug/ml), Ref: 19299148
TCMC2576
TCMT1438 Plasmodium falciparum Plasmodium falciparum D6 IC50: 1.24 (ug/ml), Ref: 8786363
IC50: 1.68 (ug/ml), Ref: 8786363
TCMC2576
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 1.24 (ug/ml), Ref: 8786363
IC50: 1.68 (ug/ml), Ref: 8786363
TCMC915
TCMT1246 Escherichia coli Escherichia coli MIC: 1 (ug/ml), Ref: 25791674
TCMC915
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2580
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 100 (ug/ml), Ref: 12398535
TCMC2580
TCMT1175 Human immunodeficiency virus Human immunodeficiency virus IC50: 17.2 (ug/ml), Ref: 10425115
TCMC2166
TCMT1211 Fusobacterium nucleatum Fusobacterium nucleatum MIC: 50 (ug/ml), Ref: 8864235
TCMC2166
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1321 Staphylococcus hominis Staphylococcus hominis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1223 Staphylococcus epidermidis Staphylococcus epidermidis MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
MIC: 32.25 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1209 Staphylococcus haemolyticus Staphylococcus haemolyticus MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1343 Staphylococcus simulans Staphylococcus simulans MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1344 Staphylococcus sciuri Staphylococcus sciuri MIC: 32 (ug/ml), Ref: 19651906
MIC50: 64 (ug/ml), Ref: 19651906
MBC: 64 (ug/ml), Ref: 19651906
MIC: 4 (ug/ml), Ref: 19651906
MIC90: 64 (ug/ml), Ref: 19651906
TCMC2166
TCMT1251 Candida albicans Candida albicans MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1246 Escherichia coli Escherichia coli MIC: 100 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC2166
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-013-0809-8
TCMC348
TCMT1232 Pseudomonas aeruginosa Pseudomonas aeruginosa MIC: 62 (ug/ml), Ref: 25813159
TCMC1788
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 100 (ug/ml), Ref: 24103427
TCMC2035
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC946
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 100 (ug/ml), Ref: 14510592
TCMC1939
TCMT1175 Human immunodeficiency virus Human immunodeficiency virus IC50: 4.3 (ug/ml), Ref: 10425115
TCMC912
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 6.21 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2014
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 10 (ug/ml), Ref: 17220400
TCMC1551
TCMT1349 Helicobacter pylori SS1 Helicobacter pylori SS1 MIC: 25 (ug/ml), Ref: 20832915
TCMC1578
TCMT1408 Colletotrichum gloeosporioides Colletotrichum gloeosporioides IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578
TCMT1245 Phytophthora cactorum Phytophthora cactorum IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC2086
TCMT1439 Mycobacterium smegmatis Mycobacterium smegmatis MIC: 100 (ug/ml), Ref: 10924184
TCMC2086
TCMT1454 Bacillus subtilis Bacillus subtilis MIC: 100 (ug/ml), Ref: 10924184
TCMC1776
TCMT1253 Penicillium chrysogenum Penicillium chrysogenum MIC: 100 (ug/ml), Ref: 10.1021/np50124a013
TCMC897
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 6.25 (ug/ml), Ref: 12762812
TCMC872
TCMT1444 Fusarium oxysporum Fusarium oxysporum MIC: 64 (ug/ml), Ref: 22850211
TCMC710
TCMT1246 Escherichia coli Escherichia coli MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710
TCMT1412 Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710
TCMT1458 Filobasidiella neoformans Cryptococcus neoformans IC50: 20 (ug/ml), Ref: 12502337
TCMC710
TCMT1251 Candida albicans Candida albicans MIC: 3 (ug/ml), Ref: 10395518
TCMC710
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710
TCMT1349 Helicobacter pylori SS1 Helicobacter pylori SS1 MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710
TCMT1442 Leishmania donovani Leishmania donovani IC50: 1.9 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1961
TCMT1349 Helicobacter pylori SS1 Helicobacter pylori SS1 MIC: 6.25 (ug/ml), Ref: 20832915
TCMC1738
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 50 (ug/ml), Ref: 10.1016/S0960-894X(00)80336-4
TCMC2822
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 6.25 (ug/ml), Ref: 17845001
TCMC1113
TCMT1093 Enoyl-acyl-carrier protein reductase Plasmodium falciparum Ki: 16 (nM), Ref: 17263522
TCMC962
TCMT1221 Human herpesvirus 4 Human herpesvirus 4 IC50: 10.2 (nM), Ref: 17503850
TCMC962
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 37 (nM), Ref: 20034711
TCMC962
TCMT1313 Human immunodeficiency virus 2 Human immunodeficiency virus type 2 (ISOLATE ROD) IC50: 37 (nM), Ref: 20034711