Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC1107	TCMT290	Muscarinic acetylcholine receptor M5	Homo sapiens	Ki: 0.14 (nM), Ref: 23707254 Ki: 0.3388 (nM), Ref: 24365159 Ki: 0.34 (nM), Ref: 24365159 Ki: 3.02 (nM), Ref: 25051097
TCMC1107	TCMT291	Muscarinic acetylcholine receptor M3	Homo sapiens	Ki: 0.2692 (nM), Ref: 24365159 Ki: 0.27 (nM), Ref: 24365159
TCMC1107	TCMT292	Muscarinic acetylcholine receptor M1	Homo sapiens	Ki: 0.2692 (nM), Ref: 24365159 Ki: 0.27 (nM), Ref: 24365159
TCMC1107	TCMT293	Muscarinic acetylcholine receptor M2	Homo sapiens	Ki: 5.012 (nM), Ref: 25051097 Ki: 12.88 (nM), Ref: 25051097 Ki: 3.631 (nM), Ref: 25051097 Ki: 2.818 (nM), Ref: 25051097
TCMC498	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 410 (nM), Ref: 26688270
TCMC498	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 6300 (nM), Ref: 26688270
TCMC2204	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 482 (nM), Ref: 21067924 Ki: 478 (nM), Ref: 22077347 Ki: 480 (nM), Ref: 26688270
TCMC2204	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 754 (nM), Ref: 22077347 Ki: 750 (nM), Ref: 26688270
TCMC2245	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 9180 (nM), Ref: 22892213
TCMC2245	TCMT225	Carbonic anhydrase XIII	Homo sapiens	Ki: 8360 (nM), Ref: 22892213
TCMC2245	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7510 (nM), Ref: 22892213
TCMC732	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 5900 (nM), Ref: 21561086
TCMC1319	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9700 (nM), Ref: 19911821
TCMC1319	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 9000 (nM), Ref: 19911821
TCMC1319	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 9800 (nM), Ref: 19911821
TCMC1319	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 2400 (nM), Ref: 19911821
TCMC1319	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 5500 (nM), Ref: 19911821
TCMC1319	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 5100 (nM), Ref: 19911821
TCMC1319	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 8300 (nM), Ref: 19911821
TCMC1319	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5900 (nM), Ref: 19911821
TCMC1551	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 1900 (nM), Ref: 16248836 Ki: 1900 (nM), Ref: 16248836 Ki: 800 (nM), Ref: 16248836 Ki: 250 (nM), Ref: 22696418
TCMC1551	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 760 (nM), Ref: 23746477
TCMC1551	TCMT268	Cytochrome P450 2A13	Homo sapiens	Ki: 40 (nM), Ref: 22696418
TCMC1999	TCMT34	Cytochrome P450 2D6	Homo sapiens	Ki: 3.3 (nM), Ref: 8487254 Ki: 4.6 (nM), Ref: 8487254 Ki: 14 (nM), Ref: 8487254 Ki: 5.7 (nM), Ref: 8487254 Ki: 3.5 (nM), Ref: 8487254 Ki: 13 (nM), Ref: 8487254 Ki: 4.6 (nM), Ref: 8487254
TCMC1961	TCMT206	Cytochrome P450 2A6	Homo sapiens	Ki: 600 (nM), Ref: 16248836
TCMC1961	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 6480 (nM), Ref: 23746477
TCMC998	TCMT154	Protein kinase C delta	Homo sapiens	Ki: 9.7 (nM), Ref: 23582444

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC1395	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 64 (ug/ml), Ref: 23369537
TCMC1210	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 30 (ug/ml), Ref: 18564877
TCMC2442	TCMT1251	Candida albicans	Candida albicans	MIC: 50 (ug/ml), Ref: 10924184
TCMC2442	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 50 (ug/ml), Ref: 10924184
TCMC2442	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 10924184
TCMC2442	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 50 (ug/ml), Ref: 10924184
TCMC2444	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 5.8 (ug/ml), Ref: 8786363 IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 5.8 (ug/ml), Ref: 8786363 IC50: 3.65 (ug/ml), Ref: 8786363
TCMC2444	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 25372601
TCMC2454	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 19.6 (ug/ml), Ref: 10425115
TCMC2550	TCMT1393	Vibrio sp.	Vibrio sp.	MIC: 15 (ug/ml), Ref: 21865038
TCMC2576	TCMT1438	Plasmodium falciparum	Plasmodium falciparum D6	IC50: 1.24 (ug/ml), Ref: 8786363 IC50: 1.68 (ug/ml), Ref: 8786363
TCMC2576	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 1.24 (ug/ml), Ref: 8786363 IC50: 1.68 (ug/ml), Ref: 8786363
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC732	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 9 (ug/ml), Ref: 9748372
TCMC2035	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC1939	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 4.3 (ug/ml), Ref: 10425115
TCMC2014	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 10 (ug/ml), Ref: 17220400
TCMC1551	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 20832915
TCMC2086	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 100 (ug/ml), Ref: 10924184
TCMC2086	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10924184
TCMC872	TCMT1444	Fusarium oxysporum	Fusarium oxysporum	MIC: 64 (ug/ml), Ref: 22850211
TCMC1961	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 6.25 (ug/ml), Ref: 20832915