Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2051	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 8710 (nM), Ref: 22892213
TCMC2051	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4050 (nM), Ref: 22892213
TCMC2051	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 960 (nM), Ref: 22892213
TCMC2093	TCMT82	Estrogen receptor alpha	Homo sapiens	IC50: 57 (nM), Ref: 17149865
TCMC2093	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 68 (nM), Ref: 17149865
TCMC983	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 2800 (nM), Ref: 15887952 IC50: 2800 (nM), Ref: 15887952 IC50: 1200 (nM), Ref: 12502307 IC50: 2800 (nM), Ref:
TCMC983	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 7300 (nM), Ref: 21030469
TCMC983	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 718.7 (nM), Ref: 26498393
TCMC983	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.2 (nM), Ref: 26498393
TCMC983	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 56.4 (nM), Ref: 26498393
TCMC2111	TCMT614	Egl nine homolog 1	Homo sapiens	IC50: 3000 (nM), Ref: 18942826
TCMC1734	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	Ki: 3430 (nM), Ref: 19097799
TCMC1734	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 4960 (nM), Ref: 18533708
TCMC1734	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 2.9 (nM), Ref: 20413308 IC50: 230 (nM), Ref: 22115839 IC50: 230 (nM), Ref: 23142320 IC50: 1200 (nM), Ref: 23994869 IC50: 3300 (nM), Ref: 24074257 IC50: 1200 (nM), Ref: 24992702 IC50: 5100 (nM), Ref: 27155469 IC50: 1000 (nM), Ref: 27155469
TCMC1734	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 3656 (nM), Ref: 20696580
TCMC1734	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 79.5 (nM), Ref: 26498393
TCMC1734	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.3 (nM), Ref: 26498393
TCMC1734	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 44.3 (nM), Ref: 26498393
TCMC1958	TCMT899	Aldehyde dehydrogenase	Homo sapiens	Ki: 450 (nM), Ref: 18613661
TCMC90	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 2400 (nM), Ref: 14592472

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1482	TCMT1136	Neuraminidase	H1N1 swine influenza virus	IC50: 4.2 (ug/ml), Ref: 21123068 IC50: 5.42 (ug/ml), Ref: 21123068 IC50: 17.98 (ug/ml), Ref: 21123068 IC50: 18.23 (ug/ml), Ref: 21123068 IC50: 19.09 (ug/ml), Ref: 21123068
TCMC1482	TCMT1121	Sialidase	Clostridium perfringens	IC50: 6.9 (ug/ml), Ref: 21123068
TCMC1482	TCMT1136	Neuraminidase	Influenza A virus	IC50: 4.2 (ug/ml), Ref: 21123068 IC50: 5.42 (ug/ml), Ref: 21123068 IC50: 17.98 (ug/ml), Ref: 21123068 IC50: 18.23 (ug/ml), Ref: 21123068 IC50: 19.09 (ug/ml), Ref: 21123068
TCMC983	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 9.43 (ug/ml), Ref: 20116898
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC2323	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 32 (ug/ml), Ref: 12932139
TCMC2051	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 42 (ug/ml), Ref: 22280816 MIC: 42.1 (ug/ml), Ref: 26112067
TCMC855	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.2 (ug/ml), Ref: 19299148
TCMC2093	TCMT1251	Candida albicans	Candida albicans	MIC: 64 (ug/ml), Ref: 12932139
TCMC2093	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 64 (ug/ml), Ref: 12932139
TCMC2397	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 2 (ug/ml), Ref: 12932139
TCMC2397	TCMT1251	Candida albicans	Candida albicans	MIC: 16 (ug/ml), Ref: 12932139
TCMC2422	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 13.6 (ug/ml), Ref: 10346950 IC50: 13.6 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2469	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 2 (ug/ml), Ref: 12932139
TCMC2469	TCMT1251	Candida albicans	Candida albicans	MIC: 16 (ug/ml), Ref: 12932139
TCMC1520	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 4 (ug/ml), Ref: 22963193
TCMC1767	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 60 (ug/ml), Ref: 20384293
TCMC1767	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1007/s00044-012-0419-x
TCMC2178	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 8 (ug/ml), Ref: 12932139
TCMC2555	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 32 (ug/ml), Ref: 12932139
TCMC2555	TCMT1251	Candida albicans	Candida albicans	MIC: 64 (ug/ml), Ref: 12932139
TCMC1482	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.2 (ug/ml), Ref: 16153842 IC50: 1.43 (ug/ml), Ref: 25137491 IC50: 1.4 (ug/ml), Ref: 10.1039/C5MD00481K IC50: 4.2 (nM), Ref: 19269069
TCMC1482	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 2 (ug/ml), Ref: 17112640
TCMC1482	TCMT1234	Bacillus coagulans	Bacillus coagulans	MIC: 2 (ug/ml), Ref: 17112640
TCMC1482	TCMT1235	Clostridium sporogenes	Clostridium sporogenes	MIC: 8 (ug/ml), Ref: 17112640
TCMC1482	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 3 (ug/ml), Ref: 17112640
TCMC1482	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3 (ug/ml), Ref: 17112640 MIC: 16 (ug/ml), Ref: 17112640 MIC: 6.25 (ug/ml), Ref: 17112640 MIC: 3.13 (ug/ml), Ref: 17112640
TCMC1482	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 6 (ug/ml), Ref: 17112640
TCMC1482	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 6 (ug/ml), Ref: 17112640
TCMC1482	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 5 (ug/ml), Ref: 17112640
TCMC1482	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 17112640
TCMC1482	TCMT1236	Mycobacterium bovis	Mycobacterium bovis	MIC: 20 (ug/ml), Ref: 17112640
TCMC1482	TCMT1237	Mycobacterium kansasii	Mycobacterium kansasii	MIC: 20 (ug/ml), Ref: 17112640
TCMC1482	TCMT1238	Mycobacterium xenopi	Mycobacterium xenopi	MIC: 20 (ug/ml), Ref: 17112640
TCMC1482	TCMT1239	Mycobacterium marinum	Mycobacterium marinum	MIC: 20 (ug/ml), Ref: 17112640
TCMC1482	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 20 (ug/ml), Ref: 17112640 MIC: 7.1 (ug/ml), Ref: 23369537
TCMC1482	TCMT1457	Leishmania major	Leishmania major	IC50: 2.5 (ug/ml), Ref: 26778149
TCMC2612	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 4 (ug/ml), Ref: 12932139
TCMC2612	TCMT1251	Candida albicans	Candida albicans	MIC: 16 (ug/ml), Ref: 12932139
TCMC2649	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 4 (ug/ml), Ref: 12932139
TCMC2649	TCMT1251	Candida albicans	Candida albicans	MIC: 16 (ug/ml), Ref: 12932139
TCMC1734	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 92.24 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2776	TCMT1251	Candida albicans	Candida albicans	MIC: 64 (ug/ml), Ref: 25871261
TCMC2777	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 3430167
TCMC2777	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 3430167
TCMC2776	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 16 (ug/ml), Ref: 16562843
TCMC1482	TCMT1186	Plasmodium yoelii yoelii	Plasmodium yoelii yoelii	IC50: 0.927 (nM), Ref: 18212104 IC50: 0.927 (nM), Ref: 22122518