Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC908	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 6000 (nM), Ref: 15689157 IC50: 6000 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC908	TCMT156	Cytochrome P450 19A1	Homo sapiens	Ki: 2600 (nM), Ref: 15267241 IC50: 1 (nM), Ref: 20413308 IC50: 800 (nM), Ref: 10.1039/C3MD00166K IC50: 500 (nM), Ref: 26301554
TCMC908	TCMT223	Aldose reductase	Homo sapiens	IC50: 8500 (nM), Ref: 18165015
TCMC908	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	IC50: 670 (nM), Ref: 19097799 Ki: 110 (nM), Ref: 19097799
TCMC908	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 153 (nM), Ref: 20696580 IC50: 1290 (nM), Ref: 23600958
TCMC908	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 84 (nM), Ref: 20696580 IC50: 54 (nM), Ref: 20832301 IC50: 570 (nM), Ref: 23600958
TCMC908	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 24 (nM), Ref: 20696580
TCMC908	TCMT87	Cytochrome P450 2C9	Homo sapiens	IC50: 5225 (nM), Ref: 20832301
TCMC908	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 5490 (nM), Ref: 22487176 Ki: 5420 (nM), Ref: 22487176
TCMC908	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 4380 (nM), Ref: 22487176 Ki: 4310 (nM), Ref: 22487176
TCMC908	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 2650 (nM), Ref: 22487176 Ki: 2710 (nM), Ref: 22487176
TCMC908	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 8960 (nM), Ref: 22487176 Ki: 9070 (nM), Ref: 22487176 Ki: 34.7 (nM), Ref: 26498393
TCMC908	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 537.75 (nM), Ref: 26498393
TCMC908	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 171.41 (nM), Ref: 26498393
TCMC1495	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 IC50: 1000 (nM), Ref: 25461324 IC50: 1000 (nM), Ref: 25461324 Ki: 9300 (nM), Ref: 27460668
TCMC1495	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 1000 (nM), Ref: 20471252 Ki: 6800 (nM), Ref: 27460668
TCMC1495	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 10000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1495	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1429	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 2700 (nM), Ref: 17378609
TCMC1429	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 1050 (nM), Ref: 18533708
TCMC1429	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 360 (nM), Ref: 18533708
TCMC1429	TCMT187	Androgen Receptor	Homo sapiens	IC50: 9700 (nM), Ref: 19592245
TCMC1429	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 716 (nM), Ref: 20696580
TCMC1429	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 632 (nM), Ref: 20696580
TCMC1429	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 47 (nM), Ref: 20696580
TCMC1429	TCMT223	Aldose reductase	Homo sapiens	IC50: 10000 (nM), Ref: 22261024
TCMC1429	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 2320 (nM), Ref: 23411073
TCMC1429	TCMT591	Estrogen-related receptor alpha	Homo sapiens	IC50: 9640 (nM), Ref: 23656512
TCMC1429	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 10000 (nM), Ref: 26322379
TCMC1429	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 9525.7 (nM), Ref: 26498393
TCMC1429	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 25 (nM), Ref: 26498393
TCMC1429	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 145.9 (nM), Ref: 26498393
TCMC1429	TCMT159	Tyrosinase	Homo sapiens	IC50: 1000 (nM), Ref: 26841168
TCMC1364	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1100 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1364	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 4000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1364	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 1600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1364	TCMT308	Oxoeicosanoid receptor 1	Homo sapiens	IC50: 2000 (nM), Ref: 24351031
TCMC1411	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1261 (nM), Ref: 20696580
TCMC1411	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 56 (nM), Ref: 20696580
TCMC1411	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 17 (nM), Ref: 20696580
TCMC1411	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 212.9 (nM), Ref: 26498393
TCMC1411	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.4 (nM), Ref: 26498393
TCMC1411	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 54.9 (nM), Ref: 26498393 Ki: 220 (nM), Ref: 26498393
TCMC1411	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 440 (nM), Ref: 26498393
TCMC737	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 168 (nM), Ref: 26498393
TCMC737	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 5591.2 (nM), Ref: 26498393
TCMC737	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 423.7 (nM), Ref: 26498393
TCMC737	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4.9 (nM), Ref: 26498393
TCMC1430	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC1741	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	IC50: 140 (nM), Ref: 17994679 IC50: 140 (nM), Ref: 18029181 Ki: 50 (nM), Ref: 18665582 IC50: 150 (nM), Ref: 18752940 IC50: 140 (nM), Ref: 19307116 IC50: 130 (nM), Ref: 18760600 IC50: 140 (nM), Ref: 19309152 IC50: 140 (nM), Ref: 19592242 IC50: 140 (nM), Ref: 19592242 Ki: 82 (nM), Ref: 20184326 Ki: 104 (nM), Ref: 20184326 IC50: 140 (nM), Ref: 20444602 IC50: 140 (nM), Ref: 20615702 IC50: 249 (nM), Ref: 25737085
TCMC2031	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 43 (nM), Ref: 16302800 IC50: 500 (nM), Ref: 24328302
TCMC1982	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 790 (nM), Ref: 17378609 IC50: 4000 (nM), Ref: 24368208
TCMC1982	TCMT223	Aldose reductase	Homo sapiens	IC50: 2200 (nM), Ref: 18165015 IC50: 14.8 (nM), Ref: 18976928 IC50: 2200 (nM), Ref: 22261024 IC50: 2900 (nM), Ref: 25152999
TCMC1982	TCMT44	Glyoxalase I	Homo sapiens	IC50: 3200 (nM), Ref: 18258440
TCMC1982	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 1540 (nM), Ref: 18533708
TCMC1982	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7890 (nM), Ref: 20185318
TCMC1982	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 8100 (nM), Ref: 20185318
TCMC1982	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2540 (nM), Ref: 20185318
TCMC1982	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 2680 (nM), Ref: 20185318
TCMC1982	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 6810 (nM), Ref: 20185318
TCMC1982	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6170 (nM), Ref: 20185318
TCMC1982	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4840 (nM), Ref: 20185318
TCMC1982	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 7000 (nM), Ref: 20185318
TCMC1982	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 9390 (nM), Ref: 20185318
TCMC1982	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 5410 (nM), Ref: 20185318
TCMC1982	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 12 (nM), Ref: 20413308
TCMC1982	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 4097 (nM), Ref: 20696580 IC50: 1550 (nM), Ref: 22328583
TCMC1982	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1191 (nM), Ref: 20696580
TCMC1982	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 77 (nM), Ref: 20696580
TCMC1982	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 6680 (nM), Ref: 22658537
TCMC1982	TCMT320	Matrix metalloproteinase 3	Homo sapiens	IC50: 5570 (nM), Ref: 22658537
TCMC1982	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 1610 (nM), Ref: 22658537
TCMC1982	TCMT322	Matrix metalloproteinase 13	Homo sapiens	IC50: 8460 (nM), Ref: 22658537
TCMC1982	TCMT422	CaM kinase II beta	Homo sapiens	IC50: 3000 (nM), Ref: 21798748
TCMC1982	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 2000 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1982	TCMT207	Beta-secretase 1	Homo sapiens	IC50: 5400 (nM), Ref: 10.1007/s00044-012-0353-y IC50: 6500 (nM), Ref: 26003344
TCMC1982	TCMT784	Vasopressin V2 receptor	Homo sapiens	IC50: 7000 (nM), Ref: 23437772 IC50: 6309.57 (nM), Ref: 23437772
TCMC1982	TCMT785	Interleukin-8 receptor A	Homo sapiens	IC50: 4500 (nM), Ref: 23437772 IC50: 5011.87 (nM), Ref: 23437772
TCMC1982	TCMT786	C-C chemokine receptor type 4	Homo sapiens	IC50: 10000 (nM), Ref: 23437772
TCMC1982	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 590 (nM), Ref: 23411073
TCMC1982	TCMT601	Thrombin	Homo sapiens	IC50: 1500 (nM), Ref: 24610996
TCMC1982	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 280 (nM), Ref: 24328302
TCMC1982	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 120 (nM), Ref: 24328302
TCMC1982	TCMT791	Protein kinase N1	Homo sapiens	IC50: 5800 (nM), Ref: 24328302
TCMC1982	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 5750 (nM), Ref: 24328302
TCMC1982	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 4230 (nM), Ref: 24328302
TCMC1982	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 5730 (nM), Ref: 24328302
TCMC1982	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 580 (nM), Ref: 24328302
TCMC1982	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 300 (nM), Ref: 24328302
TCMC1982	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 1200 (nM), Ref: 24328302
TCMC1982	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 960 (nM), Ref: 24328302
TCMC1982	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 910 (nM), Ref: 24328302
TCMC1982	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 5090 (nM), Ref: 24328302
TCMC1982	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 3320 (nM), Ref: 24328302
TCMC1982	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 5390 (nM), Ref: 24328302
TCMC1982	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 280 (nM), Ref: 25060641 IC50: 3500 (nM), Ref: 27162124
TCMC1982	TCMT793	Liver glycogen phosphorylase	Homo sapiens	IC50: 4800 (nM), Ref: 25092521
TCMC1982	TCMT33	Cytochrome P450 3A4	Homo sapiens	IC50: 2110 (nM), Ref: 22328583
TCMC1982	TCMT217	Cytochrome P450 2C8	Homo sapiens	IC50: 1390 (nM), Ref: 22328583
TCMC1982	TCMT261	Death-associated protein kinase 1	Homo sapiens	IC50: 8900 (nM), Ref: 26322379
TCMC469	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 100 (nM), Ref: 22921742
TCMC1015	TCMT318	Putative hexokinase HKDC1	Homo sapiens	IC50: 4320 (nM), Ref:
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1428	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 509 (nM), Ref: 20696580
TCMC1428	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 88 (nM), Ref: 20696580
TCMC1428	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC1898	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 7906 (nM), Ref: 20696580
TCMC1898	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 1679 (nM), Ref: 20696580
TCMC1898	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 1491 (nM), Ref: 20696580
TCMC1898	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 900 (nM), Ref: 10.1039/C3MD00166K
TCMC1788	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 600 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 5300 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 4100 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1788	TCMT126	Telomerase reverse transcriptase	Homo sapiens	IC50: 8600 (nM), Ref: 10.1039/C0MD00241K
TCMC1788	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	Ki: 1500 (nM), Ref: 27460668
TCMC1516	TCMT44	Glyoxalase I	Homo sapiens	IC50: 7700 (nM), Ref: 18258440
TCMC1516	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 3370 (nM), Ref: 20696580
TCMC1516	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 1249 (nM), Ref: 20696580
TCMC1516	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 79 (nM), Ref: 20696580
TCMC1516	TCMT83	Lymphocyte differentiation antigen CD38	Homo sapiens	IC50: 8200 (nM), Ref: 21641214
TCMC1516	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 3610 (nM), Ref: 22658537
TCMC1516	TCMT321	Matrix metalloproteinase 9	Homo sapiens	IC50: 5620 (nM), Ref: 22658537
TCMC1516	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 980 (nM), Ref: 22658537
TCMC1516	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC1516	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 830 (nM), Ref: 23411073
TCMC1516	TCMT127	Poly [ADP-ribose] polymerase-1	Homo sapiens	IC50: 4265.8 (nM), Ref: 23574272 IC50: 4200 (nM), Ref: 23574272
TCMC1516	TCMT128	Tankyrase-2	Homo sapiens	IC50: 1071.52 (nM), Ref: 23574272 IC50: 1100 (nM), Ref: 23574272
TCMC1516	TCMT129	Tankyrase-1	Homo sapiens	IC50: 2398.83 (nM), Ref: 23574272 IC50: 2400 (nM), Ref: 23574272
TCMC1516	TCMT223	Aldose reductase	Homo sapiens	IC50: 600 (nM), Ref: 23683835 IC50: 3200 (nM), Ref: 26529431
TCMC1516	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 1600 (nM), Ref: 24368208
TCMC1516	TCMT45	Beta amyloid A4 protein	Homo sapiens	IC50: 6400 (nM), Ref: 24878198
TCMC1516	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 2900 (nM), Ref: 25019478 IC50: 7800 (nM), Ref: 26096677
TCMC1516	TCMT100	Transthyretin	Homo sapiens	IC50: 7000 (nM), Ref: 26214366
TCMC1516	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 3691.6 (nM), Ref: 26498393
TCMC1516	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.7 (nM), Ref: 26498393
TCMC1516	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 60.3 (nM), Ref: 26498393
TCMC1516	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 293 (nM), Ref: 26498393
TCMC1516	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 9200 (nM), Ref: 26529431
TCMC1356	TCMT223	Aldose reductase	Homo sapiens	IC50: 3000 (nM), Ref: 22261024
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472
TCMC1832	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1700 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1700 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 9600 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1832	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC710	TCMT249	Cyclin-dependent kinase 6	Homo sapiens	IC50: 1700 (nM), Ref: 15689157 IC50: 1700 (nM), Ref: 10.1007/s00044-009-9233-5
TCMC710	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10000 (nM), Ref: 18192087 IC50: 900 (nM), Ref: 20413308 IC50: 1200 (nM), Ref: 26301554
TCMC710	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 710 (nM), Ref: 18533708
TCMC710	TCMT752	Casein kinase II alpha	Homo sapiens	IC50: 800 (nM), Ref: 19414254
TCMC710	TCMT187	Androgen Receptor	Homo sapiens	IC50: 5200 (nM), Ref: 19592245
TCMC710	TCMT219	Cytochrome P450 1A2	Homo sapiens	IC50: 795 (nM), Ref: 20696580
TCMC710	TCMT215	Cytochrome P450 1A1	Homo sapiens	IC50: 427 (nM), Ref: 20696580
TCMC710	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 25 (nM), Ref: 20696580
TCMC710	TCMT265	Glycogen synthase kinase-3 beta	Homo sapiens	IC50: 1900 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 12 (nM), Ref: 10.1007/s00044-012-0353-y
TCMC710	TCMT260	Tyrosine-protein kinase receptor FLT3	Homo sapiens	IC50: 1450 (nM), Ref: 23411073
TCMC710	TCMT128	Tankyrase-2	Homo sapiens	IC50: 2951.21 (nM), Ref: 23574272 IC50: 2900 (nM), Ref: 23574272
TCMC710	TCMT129	Tankyrase-1	Homo sapiens	IC50: 3162.28 (nM), Ref: 23574272 IC50: 3100 (nM), Ref: 23574272
TCMC710	TCMT592	Xanthine dehydrogenase	Homo sapiens	Ki: 520 (nM), Ref: 25019478 IC50: 3200 (nM), Ref: 26022844
TCMC710	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	Ki: 6000 (nM), Ref: 26529431 IC50: 6600 (nM), Ref: 26529431

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC908	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 11.62 (ug/ml), Ref: 20116898
TCMC1429	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 16.77 (ug/ml), Ref: 20116898
TCMC2257	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 15.46 (ug/ml), Ref: 20116898
TCMC2031	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 31.14 (ug/ml), Ref: 20116898
TCMC1982	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 17.65 (ug/ml), Ref: 20116898
TCMC469	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 5.4 (ug/ml), Ref: 16643034
TCMC995	TCMT1104	Sortase	Staphylococcus aureus	IC50: 18.3 (ug/ml), Ref: 16154746
TCMC1516	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 9.65 (ug/ml), Ref: 20116898
TCMC1356	TCMT1108	Integrase	Human immunodeficiency virus 1	IC50: 64.6 (ug/ml), Ref: 9461665
TCMC710	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 8.54 (ug/ml), Ref: 20116898
TCMC2324	TCMT1462	Streptococcus mutans	Streptococcus mutans	MIC: 100 (ug/ml), Ref: 1517735
TCMC2325	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 71.7 (ug/ml), Ref: 15104496
TCMC2325	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 53.8 (ug/ml), Ref: 15104496
TCMC908	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 11170636 MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1448	Enterobacter aerogenes	Enterobacter aerogenes	MIC: 50 (ug/ml), Ref: 16213726
TCMC908	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 81 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1901	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1236	Mycobacterium bovis	Mycobacterium bovis BCG	MIC: 26 (ug/ml), Ref: 18849164
TCMC1901	TCMT1217	Bacillus anthracis	Bacillus anthracis	MIC: 8 (ug/ml), Ref: 18849164
TCMC1901	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1191	Bacillus megaterium	Bacillus megaterium	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 8 (ug/ml), Ref: 18849164
TCMC1901	TCMT1260	Streptococcus agalactiae	Streptococcus agalactiae	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1322	Streptococcus mitis	Streptococcus mitis	MIC: 64 (ug/ml), Ref: 18849164
TCMC1901	TCMT1410	Listeria monocytogenes	Listeria monocytogenes	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1323	Corynebacterium pseudodiphtheriticum	Corynebacterium pseudodiphtheriticum	MIC: 16 (ug/ml), Ref: 18849164
TCMC1901	TCMT1324	Corynebacterium diphtheriae	Corynebacterium diphtheriae	MIC: 32 (ug/ml), Ref: 18849164
TCMC1901	TCMT1319	Corynebacterium xerosis	Corynebacterium xerosis	MIC: 16 (ug/ml), Ref: 18849164
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC2379	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 16.59 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC553	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0032-z
TCMC2107	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 37.5 (ug/ml), Ref: 11678648
TCMC2107	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 20542692
TCMC1429	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 7.93 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC737	TCMT1447	Respiratory syncytial virus	Respiratory syncytial virus	IC50: 26.9 (ug/ml), Ref: 15104496
TCMC737	TCMT1294	Human parainfluenza virus 3	Human parainfluenza virus 3	IC50: 35.8 (ug/ml), Ref: 15104496
TCMC737	TCMT1449	Influenza A virus	Influenza A virus	IC50: 24.5 (ug/ml), Ref: 15104496
TCMC2257	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 15.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 37.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 59.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC2472	TCMT1246	Escherichia coli	Escherichia coli	MIC: 25 (ug/ml), Ref: 23792320
TCMC2472	TCMT1410	Listeria monocytogenes	Listeria monocytogenes	MIC: 25 (ug/ml), Ref: 23792320
TCMC2472	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 12.5 (ug/ml), Ref: 23792320
TCMC2472	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 12.5 (ug/ml), Ref: 23792320
TCMC2031	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 30 (ug/ml), Ref: 12502337
TCMC2031	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 80 (ug/ml), Ref: 17394331
TCMC2487	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 11.4 (ug/ml), Ref: 23294378
TCMC2491	TCMT1251	Candida albicans	Candida albicans	MIC: 3.2 (ug/ml), Ref: 9873584
TCMC1982	TCMT1246	Escherichia coli	Escherichia coli	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 2 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 1 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 3.9 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 IC50: 3.8 (ug/ml), Ref: 24749980
TCMC1982	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7 MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC: 31.25 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 62.5 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC1982	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 50 (ug/ml), Ref: 12762812 MIC: 100 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC1982	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 50 (ug/ml), Ref: 12762812
TCMC1982	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 6.5 (ug/ml), Ref: 12398543
TCMC1982	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 29.5 (ug/ml), Ref: 12398543 IC50: 1 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.4 (ug/ml), Ref: 18855442
TCMC1982	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 64 (ug/ml), Ref: 20655215 MIC: 64 (ug/ml), Ref: 21534606
TCMC1982	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 6 (ug/ml), Ref: 17394331
TCMC1982	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 50 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1428	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC1428	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 25 (ug/ml), Ref: 12762812
TCMC1428	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 32.7 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 26 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1898	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 12.5 (ug/ml), Ref: 22280816
TCMC1898	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 80.76 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1898	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 73 (ug/ml), Ref: 10.1007/s00044-013-0485-8 MIC: 63.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC1788	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 100 (ug/ml), Ref: 24103427
TCMC1516	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1246	Escherichia coli	Escherichia coli	MIC: 50 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 64 (ug/ml), Ref: 12608861 MIC: 4 (ug/ml), Ref: 22677320
TCMC1516	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268 MIC: 50 (ug/ml), Ref: 18313801 MIC: 18 (ug/ml), Ref: 22677320 MIC: 9 (ug/ml), Ref: 22677320
TCMC1516	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 17027268
TCMC1516	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 25 (ug/ml), Ref: 18313801
TCMC1516	TCMT1213	Neisseria gonorrhoeae	Neisseria gonorrhoeae	MIC: 16 (ug/ml), Ref: 12608861
TCMC1516	TCMT1212	Verticillium dahliae	Verticillium dahliae	IC50: 7 (ug/ml), Ref: 17394331
TCMC1516	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 17.8 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1516	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0268-7
TCMC1516	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 0.8 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1356	TCMT1215	Pseudomonas aeruginosa PAO1	Pseudomonas aeruginosa PAO1	MIC: 32 (ug/ml), Ref: 21534606
TCMC1356	TCMT1208	Escherichia coli K12	Escherichia coli K-12	MIC: 16 (ug/ml), Ref: 21534606
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812
TCMC2688	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 50 (ug/ml), Ref: 14969530
TCMC2688	TCMT1282	Colletotrichum orbiculare	Colletotrichum orbiculare	MIC: 30 (ug/ml), Ref: 14969530
TCMC2707	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 0.03 (ug/ml), Ref: 3373488 MIC: 0.016 (ug/ml), Ref: 3373488 MIC: 0.06 (ug/ml), Ref: 3373488
TCMC2707	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 2 (ug/ml), Ref: 3373488 MIC: 4 (ug/ml), Ref: 3373488
TCMC2707	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.13 (ug/ml), Ref: 3373488 MIC: 0.25 (ug/ml), Ref: 3373488
TCMC2707	TCMT1246	Escherichia coli	Escherichia coli	MIC: 1 (ug/ml), Ref: 3373488 MIC: 2 (ug/ml), Ref: 3373488 MIC: 8 (ug/ml), Ref: 3373488
TCMC2707	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 2 (ug/ml), Ref: 3373488 MIC: 8 (ug/ml), Ref: 3373488
TCMC2707	TCMT1224	Proteus mirabilis	Proteus mirabilis	MIC: 0.25 (ug/ml), Ref: 3373488 MIC: 1 (ug/ml), Ref: 3373488
TCMC2707	TCMT1177	Haemophilus influenzae	Haemophilus influenzae	MIC: 2 (ug/ml), Ref: 3373488 MIC: 4 (ug/ml), Ref: 3373488 MIC: 2 (ug/ml), Ref: 18347113 MIC: 4 (ug/ml), Ref: 18347113
TCMC710	TCMT1246	Escherichia coli	Escherichia coli	MIC: 7.8 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1412	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	MIC: 15.6 (ug/ml), Ref: 10.1016/S0960-894X(01)80881-7
TCMC710	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	IC50: 20 (ug/ml), Ref: 12502337
TCMC710	TCMT1251	Candida albicans	Candida albicans	MIC: 3 (ug/ml), Ref: 10395518
TCMC710	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 12.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC710	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1349	Helicobacter pylori SS1	Helicobacter pylori SS1	MIC: 25 (ug/ml), Ref: 10.1007/s00044-012-0207-7
TCMC710	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 1.9 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1982	TCMT1093	Enoyl-acyl-carrier protein reductase	Plasmodium falciparum	Ki: 22 (nM), Ref: 17263522