Targeted Human Proteins by the Ingredients of Prescription
References are linked to referred publications via PubMed ID or DOI.There may be multiple activity records for a specific ingredient-target pair.
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| Ingredient ID & Structure | Target ID | Target Name | Target Organism | Activity Records & Reference |
|---|---|---|---|---|
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TCMT136 | Carbonic anhydrase XII | Homo sapiens |
Ki: 8900 (nM), Ref: 19911821 |
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TCMT135 | Carbonic anhydrase XIV | Homo sapiens |
Ki: 48 (nM), Ref: 19911821 |
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TCMT137 | Carbonic anhydrase IX | Homo sapiens |
Ki: 9100 (nM), Ref: 19911821 |
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TCMT138 | Carbonic anhydrase VII | Homo sapiens |
Ki: 3300 (nM), Ref: 19911821 |
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TCMT139 | Carbonic anhydrase VI | Homo sapiens |
Ki: 2000 (nM), Ref: 19911821 |
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TCMT140 | Carbonic anhydrase VB | Homo sapiens |
Ki: 5200 (nM), Ref: 19911821 |
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TCMT141 | Carbonic anhydrase VA | Homo sapiens |
Ki: 9400 (nM), Ref: 19911821 |
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TCMT142 | Carbonic anhydrase IV | Homo sapiens |
Ki: 6800 (nM), Ref: 19911821 |
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TCMT143 | Carbonic anhydrase III | Homo sapiens |
Ki: 5600 (nM), Ref: 19911821 |
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TCMT133 | Carbonic anhydrase I | Homo sapiens |
Ki: 3100 (nM), Ref: 19911821 Ki: 3100 (nM), Ref: 21067924 Ki: 3100 (nM), Ref: 22137345 Ki: 3100 (nM), Ref: 22077347 Ki: 3100 (nM), Ref: 22365761 Ki: 3100 (nM), Ref: 22377674 Ki: 3100 (nM), Ref: 23241068 Ki: 3100 (nM), Ref: 22892213 Ki: 3100 (nM), Ref: 26688270 |
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TCMT134 | Carbonic anhydrase II | Homo sapiens |
Ki: 9200 (nM), Ref: 21067924 Ki: 9200 (nM), Ref: 22137345 Ki: 9200 (nM), Ref: 22077347 Ki: 9200 (nM), Ref: 22365761 Ki: 9200 (nM), Ref: 22377674 Ki: 9200 (nM), Ref: 23241068 Ki: 9200 (nM), Ref: 22892213 Ki: 9200 (nM), Ref: 26688270 |
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TCMT133 | Carbonic anhydrase I | Homo sapiens |
Ki: 1080 (nM), Ref: 21282059 |
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TCMT134 | Carbonic anhydrase II | Homo sapiens |
Ki: 470 (nM), Ref: 21282059 |
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TCMT137 | Carbonic anhydrase IX | Homo sapiens |
Ki: 4450 (nM), Ref: 21282059 |
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TCMT136 | Carbonic anhydrase XII | Homo sapiens |
Ki: 4090 (nM), Ref: 21282059 |
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TCMT139 | Carbonic anhydrase VI | Homo sapiens |
Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439 |
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TCMT142 | Carbonic anhydrase IV | Homo sapiens |
Ki: 2450 (nM), Ref: 22687439 |
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TCMT135 | Carbonic anhydrase XIV | Homo sapiens |
Ki: 690 (nM), Ref: 22668600 |
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TCMT138 | Carbonic anhydrase VII | Homo sapiens |
Ki: 7870 (nM), Ref: 22668600 |
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TCMT47 | Apoptosis regulator Bcl-2 | Homo sapiens |
Ki: 400 (nM), Ref: 10.1007/s00044-009-9233-5 |
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TCMT161 | Hydroxycarboxylic acid receptor 2 | Homo sapiens |
Ki: 4900 (nM), Ref: 21167710 |
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TCMT133 | Carbonic anhydrase I | Homo sapiens |
Ki: 3100 (nM), Ref: 20674354 Ki: 3100 (nM), Ref: 21282059 Ki: 3400 (nM), Ref: 22137345 |
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TCMT134 | Carbonic anhydrase II | Homo sapiens |
Ki: 9200 (nM), Ref: 20674354 Ki: 9200 (nM), Ref: 21282059 Ki: 9300 (nM), Ref: 22137345 |
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TCMT82 | Estrogen receptor alpha | Homo sapiens |
IC50: 1.3 (nM), Ref: 15203155 IC50: 3 (nM), Ref: 10673099 IC50: 1.3 (nM), Ref: 15203156 Ki: 100 (nM), Ref: 12954056 IC50: 2 (nM), Ref: 12749898 IC50: 5.9 (nM), Ref: 10447957 IC50: 1.3 (nM), Ref: 15745820 IC50: 1.3 (nM), Ref: 15664843 IC50: 1.3 (nM), Ref: 15582421 IC50: 1.3 (nM), Ref: 15225685 IC50: 1.3 (nM), Ref: 15225686 IC50: 3.2 (nM), Ref: 15341953 IC50: 3.2 (nM), Ref: 15456246 IC50: 3.2 (nM), Ref: 15876535 IC50: 3.2 (nM), Ref: 15943471 IC50: 28 (nM), Ref: 15658851 Ki: 1.995 (nM), Ref: 15771467 IC50: 3.2 (nM), Ref: 16098741 IC50: 0.75 (nM), Ref: 16219463 IC50: 1.4 (nM), Ref: 16309907 IC50: 1.35 (nM), Ref: 16412638 IC50: 10 (nM), Ref: 16610787 IC50: 1.3 (nM), Ref: 16632357 IC50: 1.3 (nM), Ref: 16730987 IC50: 46 (nM), Ref: 16942012 IC50: 1.6 (nM), Ref: 16942012 IC50: 1.3 (nM), Ref: 16777408 IC50: 1.2 (nM), Ref: 17149865 IC50: 4.7 (nM), Ref: 17696335 IC50: 3.6 (nM), Ref: 17049855 IC50: 3.2 (nM), Ref: 17188490 IC50: 1 (nM), Ref: 17289385 IC50: 1.4 (nM), Ref: 17448656 IC50: 1.4 (nM), Ref: 17890084 IC50: 4 (nM), Ref: 18760603 Ki: 2 (nM), Ref: 18722117 IC50: 12.5 (nM), Ref: 19836949 IC50: 3.2 (nM), Ref: 19705860 Ki: 0.16 (nM), Ref: 20621492 IC50: 21.04 (nM), Ref: 20812681 IC50: 46 (nM), Ref: 20875743 IC50: 1.3 (nM), Ref: 24315190 IC50: 5.7 (nM), Ref: 25369367 IC50: 0.9 (nM), Ref: 26183544 Ki: 0.21 (nM), Ref: Ki: 0.21 (nM), Ref: IC50: 1.7 (nM), Ref: 27407030 |
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TCMT236 | Estrogen receptor beta | Homo sapiens |
IC50: 1.1 (nM), Ref: 15203155 IC50: 4 (nM), Ref: 10673099 IC50: 1.1 (nM), Ref: 15203156 Ki: 100 (nM), Ref: 12954056 IC50: 2 (nM), Ref: 12749898 IC50: 1.1 (nM), Ref: 15745820 IC50: 1.1 (nM), Ref: 15664843 IC50: 1.1 (nM), Ref: 15993065 IC50: 1.1 (nM), Ref: 15582421 IC50: 1.1 (nM), Ref: 15225685 IC50: 1.1 (nM), Ref: 15225686 IC50: 3.6 (nM), Ref: 15341953 IC50: 3.6 (nM), Ref: 15456246 IC50: 3.6 (nM), Ref: 15876535 IC50: 3.6 (nM), Ref: 15943471 IC50: 24 (nM), Ref: 15658851 Ki: 3.162 (nM), Ref: 15771467 IC50: 3.6 (nM), Ref: 16098741 IC50: 1.18 (nM), Ref: 16219463 IC50: 1.2 (nM), Ref: 16309907 IC50: 1.2 (nM), Ref: 16412638 IC50: 11 (nM), Ref: 16610787 IC50: 1.2 (nM), Ref: 16632357 IC50: 1.2 (nM), Ref: 16730987 IC50: 1.4 (nM), Ref: 16942012 IC50: 1.1 (nM), Ref: 16777408 IC50: 1.4 (nM), Ref: 17149865 IC50: 16.7 (nM), Ref: 17696335 IC50: 3.2 (nM), Ref: 17049855 IC50: 3.6 (nM), Ref: 17188490 IC50: 1 (nM), Ref: 17289385 IC50: 1.2 (nM), Ref: 17448656 IC50: 1.2 (nM), Ref: 17890084 IC50: 4 (nM), Ref: 18760603 Ki: 2 (nM), Ref: 18722117 IC50: 2.9 (nM), Ref: 19705860 IC50: 10.74 (nM), Ref: 20812681 IC50: 0.046 (nM), Ref: 24315190 IC50: 5.6 (nM), Ref: 25369367 Ki: 0.015 (nM), Ref: Ki: 0.015 (nM), Ref: IC50: 3 (nM), Ref: 27407030 |
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TCMT187 | Androgen Receptor | Homo sapiens |
IC50: 19.1 (nM), Ref: 16309907 |
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TCMT99 | Testis-specific androgen-binding protein | Homo sapiens |
IC50: 50 (nM), Ref: 17149875 |
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TCMT591 | Estrogen-related receptor alpha | Homo sapiens |
IC50: 3.6 (nM), Ref: 17482813 IC50: 6 (nM), Ref: 23448346 |
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TCMT910 | Estrogen-related receptor beta | Homo sapiens |
IC50: 3.2 (nM), Ref: 17482813 IC50: 8.7 (nM), Ref: 23448346 |
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TCMT344 | Aldehyde oxidase | Homo sapiens |
IC50: 80 (nM), Ref: 20853847 Ki: 4400 (nM), Ref: 22996261 Ki: 870 (nM), Ref: 22996261 |
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TCMT974 | G-protein coupled estrogen receptor 1 | Homo sapiens |
Ki: 5.7 (nM), Ref: 23672690 Ki: 2.7 (nM), Ref: 10.1039/C5MD00455A |
