Description of the Component
Component ID |
TCMH920 |
Latin Name |
Quercus dentata |
English Name |
NA |
Chinese Pinyin Name |
Hu Ye Gan Jin Gao |
中文名 |
槲叶干浸膏 |
TCM Properties |
|
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
|
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
GBVG156-11, GBVG154-11 |
Barcode Source |
BOLDSYSTEMS |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMFx679 | Mi Shi Tong Capsule | 泌石通胶囊 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT11 | HIF1A | Hypoxia-inducible factor 1 alpha | Transcription factor | Q16665 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT132 | BCHE | Butyrylcholinesterase | Hydrolase | P06276 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT186 | MAOB | Monoamine oxidase B | Oxidoreductase | P27338 |
| TCMT195 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | Kinase | Q02750 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT212 | SRC | Tyrosine-protein kinase SRC | Kinase | P12931 |
| TCMT213 | SLC22A1 | Solute carrier family 22 member 1 | Transporter | O15245 |
| TCMT217 | CYP2C8 | Cytochrome P450 2C8 | Oxidoreductase | P10632 |
| TCMT218 | CYP2B6 | Cytochrome P450 2B6 | Oxidoreductase | P20813 |
| TCMT219 | CYP1A2 | Cytochrome P450 1A2 | Oxidoreductase | P05177 |
| TCMT22 | ALPI | Intestinal alkaline phosphatase | Hydrolase | P09923 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT23 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | Hydrolase | P05186 |
| TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
| TCMT240 | AMY1A | Salivary alpha-amylase | Unclassified | P04745 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT276 | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | Transporter | O94956 |
| TCMT277 | SLCO1B3 | Solute carrier organic anion transporter family member 1B3 | Transporter | Q9NPD5 |
| TCMT278 | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Transporter | Q9Y6L6 |
| TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT307 | KCNH2 | HERG | Ion channel | Q12809 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT320 | MMP3 | Matrix metalloproteinase 3 | Hydrolase | P08254 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT369 | IGF1R | Insulin-like growth factor I receptor | Kinase | P08069 |
| TCMT370 | KDR | Vascular endothelial growth factor receptor 2 | Kinase | P35968 |
| TCMT374 | AURKB | Serine/threonine-protein kinase Aurora-B | Kinase | Q96GD4 |
| TCMT38 | DRD2 | Dopamine D2 receptor | GPCR | P14416 |
| TCMT388 | AXL | Tyrosine-protein kinase receptor UFO | Kinase | P30530 |
| TCMT401 | MET | Hepatocyte growth factor receptor | Kinase | P08581 |
| TCMT402 | ALK | ALK tyrosine kinase receptor | Kinase | Q9UM73 |
| TCMT436 | NUAK1 | NUAK family SNF1-like kinase 1 | Kinase | O60285 |
| TCMT441 | PTK2 | Focal adhesion kinase 1 | Kinase | Q05397 |
| TCMT445 | NEK2 | Serine/threonine-protein kinase NEK2 | Kinase | P51955 |
| TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
| TCMT462 | NEK6 | Serine/threonine-protein kinase NEK6 | Kinase | Q9HC98 |
| TCMT47 | BCL2 | Apoptosis regulator Bcl-2 | Ion channel | P10415 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT484 | PLK1 | Serine/threonine-protein kinase PLK1 | Kinase | P53350 |
| TCMT555 | HDAC6 | Histone deacetylase 6 | Hydrolase | Q9UBN7 |
| TCMT556 | HDAC2 | Histone deacetylase 2 | Hydrolase | Q92769 |
| TCMT557 | HDAC1 | Histone deacetylase 1 | Hydrolase | Q13547 |
| TCMT571 | ADORA2B | Adenosine A2b receptor | GPCR | P29275 |
| TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
| TCMT60 | FASN | Fatty acid synthase | Unclassified | P49327 |
| TCMT601 | F2 | Thrombin | Unclassified | P00734 |
| TCMT609 | CTSL | Cathepsin L | Unclassified | P07711 |
| TCMT651 | DRD3 | Dopamine D3 receptor | GPCR | P35462 |
| TCMT690 | HDAC3 | Histone deacetylase 3 | Hydrolase | O15379 |
| TCMT691 | HDAC8 | Histone deacetylase 8 | Hydrolase | Q9BY41 |
| TCMT707 | ADORA2A | Adenosine A2a receptor | GPCR | P29274 |
| TCMT729 | PIK3CA | PI3-kinase p110-alpha subunit | Transferase | P42336 |
| TCMT730 | PIK3CB | PI3-kinase p110-beta subunit | Transferase | P42338 |
| TCMT740 | PIK3CG | PI3-kinase p110-gamma subunit | Transferase | P48736 |
| TCMT791 | PKN1 | Protein kinase N1 | Kinase | Q16512 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT860 | HDAC10 | Histone deacetylase 10 | Hydrolase | Q969S8 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1175 | Human immunodeficiency virus |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1218 | Staphylococcus aureus |
| TCMT1222 | Plasmodium falciparum D6 |
| TCMT1251 | Candida albicans |
| TCMT1286 | Bacillus cereus |
| TCMT1346 | Helicobacter pylori |
| TCMT1438 | Plasmodium falciparum |
| TCMT1465 | Entamoeba histolytica |
Ingredient Structrues
Ingredient ID: TCMC913
Formula: C15H14O6
Ingredient ID: TCMC904
Formula: C5H14NO
Ingredient ID: TCMC897
Formula: C16H18O9
Ingredient ID: TCMC850
Formula: C8H10N4O2
Ingredient ID: TCMC49
Formula: C10H13NO2
Ingredient ID: TCMC2675
Formula: C30H26O12
Ingredient ID: TCMC2633
Formula: C30H24O12
Ingredient ID: TCMC2580
Formula: C30H26O12
Ingredient ID: TCMC2156
Formula: C7H8N4O2
Ingredient ID: TCMC1956
Formula: C7H6O4
Ingredient ID: TCMC1939
Formula: C45H38O18
Ingredient ID: TCMC1936
Formula: C30H24O12
Ingredient ID: TCMC1670
Formula: C75H62O30
Ingredient ID: TCMC13
Formula: C15H14O6
Ingredient ID: TCMC1295
Formula: C20H18O11
Ingredient ID: TCMC1115
Formula: C18H14O8
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC13 | C15H14O6 | (-)-Epicatechin | 290.08 | -2.494 | 2.45 | 0.406 | 1 | 5 | 110.38 | 6 | 3 | 21 | 0 |
| TCMC49 | C10H13NO2 | (1S)-1-Methyl-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol | 179.09 | -1.0729 | 2.23 | 0.899 | 1 | 3 | 52.49 | 3 | 2 | 13 | 0 |
| TCMC850 | C8H10N4O2 | Caffeine | 194.08 | -0.4311 | 1.68 | -0.625 | 6 | 0 | 58.44 | 3 | 2 | 14 | 0 |
| TCMC897 | C16H18O9 | Chlorogenic Acid | 354.1 | -2.1962 | 2.23 | -0.447 | 7 | 6 | 164.75 | 11 | 2 | 25 | 1 |
| TCMC904 | C5H14NO | Choline | 104.11 | -1.5741 | 1.79 | -0.837 | 1 | 1 | 20.23 | 6 | 0 | 7 | 0 |
| TCMC913 | C15H14O6 | Cianidanol | 290.08 | -2.494 | 2.45 | 0.406 | 1 | 5 | 110.38 | 6 | 3 | 21 | 0 |
| TCMC1115 | C18H14O8 | Epicoccolide B | 358.07 | -1.5564 | 2.56 | 1.211 | 2 | 5 | 148.43 | 10 | 3 | 26 | 0 |
| TCMC1295 | C20H18O11 | Guajaverin | 434.08 | -4.3814 | 2.45 | -0.111 | 6 | 7 | 186.37 | 10 | 4 | 31 | 1 |
| TCMC1670 | C75H62O30 | 1442.33 | -13.2432 | 6.41 | -0.558 | 5 | 25 | 551.9 | 34 | 15 | 105 | 1 | |
| TCMC1936 | C30H24O12 | Proanthocyanidin A1 | 576.13 | -4.8047 | 3.44 | 0.605 | 2 | 9 | 209.76 | 11 | 7 | 42 | 1 |
| TCMC1939 | C45H38O18 | Procyanidin C1 | 866.21 | -7.8686 | 4.43 | -0.076 | 3 | 15 | 331.14 | 20 | 9 | 63 | 1 |
| TCMC1956 | C7H6O4 | Protocatechuic Acid | 154.03 | -1.1604 | 1.79 | 0.536 | 2 | 3 | 77.76 | 4 | 1 | 11 | 0 |
| TCMC2156 | C7H8N4O2 | Theobromine | 180.06 | -0.6264 | 1.57 | -0.432 | 6 | 1 | 70.72 | 3 | 2 | 13 | 0 |
| TCMC2580 | C30H26O12 | Procyanidin B2 | 578.14 | -5.1813 | 3.44 | 0.165 | 2 | 10 | 220.76 | 13 | 6 | 42 | 1 |
| TCMC2633 | C30H24O12 | Proanthocyanidin A2 | 576.13 | -4.8047 | 3.44 | 0.605 | 2 | 9 | 209.76 | 11 | 7 | 42 | 1 |
| TCMC2675 | C30H26O12 | Procyanidin B5 | 578.14 | -5.1813 | 3.44 | 0.165 | 2 | 10 | 220.76 | 13 | 6 | 42 | 1 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
