TCM-ID Component

Description of the Component

Component ID	TCMH727
Latin Name	Aristolochia fangchi
English Name	Fangchi
Chinese Pinyin Name	Guang Fang Ji
中文名	广防己
TCM Properties
TCM Meridians
Therapeutic Class English	For dispelling wind-dampness
Therapeutic Class Chinese	祛风湿
Functions	dispel wind, relieve pain, reduce heat and induce diuresis
Toxicity	NA
Geo-authentic habitats (道地产区)	Guangdong Province,Hong Kong,Macao
Reference	CFDA
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMF3440	Feng Shi Ling Xian Oral Liquid	风湿灵仙液
TCMFx3150	Fu Fang Xia Tian Wu Tablets	复方夏天无片
TCMF3427	Fu Shen Ning Tablets	复肾宁片
TCMF3532	Gu Xian Tablets	骨仙片
TCMFx6659	Yan Jian Ning Tablets	炎见宁片

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1465	Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC722
Formula: C17H11NO7

Common Name	Aristolochic Acid
IUPAC Name	n.a.
Canonical SMILES	COc1cccc2c1cc(N(=O)=O)c1c2c2OCOc2cc1C(=O)O
Standard InCHI	InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20)
Standard InCHIKey	BBFQZRXNYIEMAW-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL93353]; PubChem [2236];
Reference of Component-Ingredient Pair	21526364

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH799	Sinomenium acutum	Han Fang Ji	汉防己
TCMH2685	Aristolochia kaempferi	Zhu Sha Lian	朱砂莲
TCMH1693	Aristolochia debilis	Qing Mu Xiang	青木香
TCMH2239	Asarum sieboldii	Xi Xin	细辛
TCMH1680	Sinomenium acutum	Qing Feng Teng	青风藤
TCMH565	Stephania tetrandra	Fang Ji	防己
TCMH1531	Akebia quinata	Mu Tong	木通
TCMH718	Aristolochia manshuriensis	Guan Mu Tong	关木通
TCMH727	Aristolochia fangchi	Guang Fang Ji	广防己
TCMH1397	Aristolochia debilis	Ma Dou Ling	马兜铃

Ingredient ID: TCMC655
Formula: C4H6N4O3

Common Name	Allantoin
IUPAC Name	(2,5-dioxoimidazolidin-4-yl)urea
Canonical SMILES	OC(=N)NC1N=C(N=C1O)O
Standard InCHI	InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)
Standard InCHIKey	POJWUDADGALRAB-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL593429]; PubChem [204];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1693	Aristolochia debilis	Qing Mu Xiang	青木香
TCMH2538	Zea mays	Yu Mi Xu	玉米须
TCMH679	Pueraria lobata	Ge Hua	葛花
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1396	Portulaca oleracea	Ma Chi Xian	马齿苋
TCMH2300	Triticum aestivum	Xiao Mai	小麦
TCMH1588	Achyranthes bidentata	Niu Xi	牛膝
TCMH1880	Moschus moschiferus	She Xiang	麝香
TCMH2358	Aristolochia mollissima	Xun Gu Feng	寻骨风
TCMH727	Aristolochia fangchi	Guang Fang Ji	广防己
TCMH1584	Achyranthes bidentata	Niu Teng	牛藤
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH1397	Aristolochia debilis	Ma Dou Ling	马兜铃
TCMH1462	Moschus moschiferus	Mao She Xiang	毛麝香
TCMH1463	Moschus moschiferus	Mao She Xiang Jin Gao	毛麝香浸膏
TCMH1717	Moschus moschiferus	Ren Gong She Xiang	人工麝香
TCMH644	Pueraria lobata	Gan Ge	干葛
TCMH677	Pueraria lobata	Ge Gen	葛根
TCMH678	Pueraria lobata	Ge Gen Gan Jin Gao	葛根干浸膏
TCMH250	Triticum aestivum	Chen Xiao Mai Fen	陈小麦粉

Ingredient ID: TCMC2383
Formula: C20H23NO4

Common Name	Magnoflorine
IUPAC Name	(6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol
Canonical SMILES	COc1ccc2c(c1O)c1c(O)c(OC)cc3c1[C@H](C2)[N+](C)(C)CC3
Standard InCHI	InChI=1S/C20H23NO4/c1-21(2)8-7-12-10-15(25-4)20(23)18-16(12)13(21)9-11-5-6-14(24-3)19(22)17(11)18/h5-6,10,13H,7-9H2,1-4H3,(H-,22,23)/p+1/t13-/m0/s1
Standard InCHIKey	YLRXAIKMLINXQY-ZDUSSCGKSA-O
External Identifiers	ChEMBL [CHEMBL235428]; PubChem [73337];
Reference of Component-Ingredient Pair	24709313

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1416	Thalictrum foliolosum	Ma Wei Lian	马尾连
TCMH799	Sinomenium acutum	Han Fang Ji	汉防己
TCMH2580	Coptis chinensis	Ze Xi Huang Lian	择细黄连
TCMH1693	Aristolochia debilis	Qing Mu Xiang	青木香
TCMH1765	Cortex berberidis	San Ke Zhen Pi	三棵针皮
TCMH1825	Litsea cubeba	Shan Jiang Zi	山姜子
TCMH2374	Phellodendron amurense	Yan Guan Huang Bai	盐关黄柏
TCMH388	Ziziphus jujuba	Da Zao	大枣
TCMH555	Potentilla discolor	Fan Bai Cao	翻白草
TCMH1680	Sinomenium acutum	Qing Feng Teng	青风藤
TCMH565	Stephania tetrandra	Fang Ji	防己
TCMH1102	Tinospora capillipes	Jin Guo Lan	金果榄
TCMH2376	Corydalis yanhusuo	Yan Hu Suo	延胡索
TCMH1516	Cocculus trilobus	Mu Fang Ji	木防己
TCMH140	Menispermum dauricum	Bei Dou Gen	北豆根
TCMH718	Aristolochia manshuriensis	Guan Mu Tong	关木通
TCMH727	Aristolochia fangchi	Guang Fang Ji	广防己
TCMH1764	Cortex berberidis	San Ke Zhen	三棵针
TCMH717	Phellodendron amurense	Guan Huang Bai	关黄柏
TCMH949	Phellodendron amurense	Huang Bai	黄柏
TCMH950	Phellodendron amurense	Huang Bai Fen	黄柏粉
TCMH951	Phellodendron amurense	Huang Bai Tan	黄柏炭
TCMH1397	Aristolochia debilis	Ma Dou Ling	马兜铃
TCMH511	Litsea cubeba	Dou Chi Jiang	豆豉姜
TCMH1812	Litsea cubeba	Shan Cang Zi	山苍子
TCMH283	Coptis chinensis	Chuan Huang Lian	川黄连
TCMH972	Coptis chinensis	Huang Lian	黄连
TCMH973	Coptis chinensis	Huang Lian Gan Jin Gao	黄连干浸膏
TCMH975	Coptis chinensis	Huang Lian Xu	黄连须
TCMH1064	Coptis chinensis	Jiang Huang Lian	姜黄连
TCMH1161	Coptis chinensis	Jiu Huang Lian	酒黄连
TCMH2330	Coptis chinensis	Xiong Huang Lian	雄黄连
TCMH2531	Coptis chinensis	Yu Huang Lian	萸黄连

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom
TCMC655	C4H6N4O3	Allantoin	158.04	-0.2279	1.13	-0.469	7	5	121.29	5	1	11
TCMC722	C17H11NO7	Aristolochic Acid	341.05	0.0658	2.45	2.79	2	1	108.13	6	4	25
TCMC2383	C20H23NO4	Magnoflorine	342.17	-1.9843	3.11	1.008	0	2	58.92	8	4	25

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Aristolochia fangchi 广防己

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC722

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC655

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2383

Occurrence of the ingredient across TCM components

Properties

Download Data