Component: Aconitum coreanum 关白附


Description of the Component

Component ID
TCMH714
Latin Name
Aconitum coreanum
English Name
Korean monk's hood
Chinese Pinyin Name
Guan Bai Fu
中文名
关白附
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
Jilin Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
MH047588
Barcode Source
GenBank

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3521 Chuang Shang Powder 创伤散
TCMFx6012 Xiao Er Jing Feng Tablets 小儿惊风片
TCMFx6101 Zhi Shang Powder 治伤散

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT164 PTGS1 Cyclooxygenase-1 Oxidoreductase P23219
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT221 ABCB11 Bile salt export pump Transporter O95342
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC406
Formula: C14H18N2O2

Ingredient ID: TCMC2404
Formula: C30H50

Ingredient ID: TCMC2037
Formula: C7H6O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC406 C14H18N2O2 3-(1H-Indol-3-Yl)-2-(Trimethylazaniumyl)Propanoate 246.14 -2.5697 2.56 1.163 3 1 55.92 8 2 18 0
TCMC2037 C7H6O3 Salicylic Acid 138.03 -0.7001 1.9 2.264 2 2 57.53 3 1 10 0
TCMC2404 C30H50 Squalene 410.39 8.5524 4.76 11.482 0 0 0 23 0 30 2

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)