Component: Atropa belladonna 颠茄浸膏


Description of the Component

Component ID
TCMH471
Latin Name
Atropa belladonna
English Name
belladonna
Chinese Pinyin Name
Dian Qie Jin Gao
中文名
颠茄浸膏
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
AY028147
Barcode Source
GenBank

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx1170 Dian Qie Tablet 颠茄片
TCMFx4691 Long Ma Lu Wei Yao Tablets 陇马陆胃药片
TCMFx5753 Shang Shi Zhen Tong Ointment 伤湿镇痛膏
TCMFx5195 She Xiang Qu Feng Shi Ointment 麝香祛风湿膏
TCMF5384 Shen Qu Wei Tong Capsules 神曲胃痛胶囊
TCMF5393 Shen Qu Wei Tong Tablets 神曲胃痛片
TCMFx5641 Wei Fu Ning Capsules 胃复宁胶囊
TCMF126 Wei Kang Ling Granules 胃康灵颗粒
TCMF125 Wei Kang Ling Tablets 胃康灵片
TCMFx5836 Wei Tong Shu Tablets 胃痛舒片
TCMF6452 Xiao Yu Ding Tong Ointment 消瘀定痛膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT193 RELA Nuclear factor NF-kappa-B p65 subunit Transcription factor Q04206
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT290 CHRM5 Muscarinic acetylcholine receptor M5 GPCR P08912
TCMT291 CHRM3 Muscarinic acetylcholine receptor M3 GPCR P20309
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1393 Vibrio sp.
TCMT1455 Mycobacterium tuberculosis H37Rv

Ingredient Structrues

Ingredient ID: TCMC50
Formula: C8H15NO

Ingredient ID: TCMC2550
Formula: C15H24

Ingredient ID: TCMC2204
Formula: C9H6O3

Ingredient ID: TCMC2051
Formula: C10H8O4

Ingredient ID: TCMC200
Formula: C17H23NO3

Ingredient ID: TCMC1999
Formula: C21H24N2O3

Ingredient ID: TCMC1660
Formula: C21H24N2O3

Ingredient ID: TCMC1107
Formula: C17H23NO3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC50 C8H15NO (1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Ol 141.12 -1.648 2.12 0.477 2 1 23.47 2 2 10 0
TCMC200 C17H23NO3 [(1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Yl] (2R)-3-Hydroxy-2-Phenylpropanoate 289.17 -1.8722 2.89 3.538 4 1 49.77 7 3 21 0
TCMC1107 C17H23NO3 Endo-Atropine 289.17 -1.8722 2.89 3.538 4 1 49.77 7 3 21 0
TCMC1660 C21H24N2O3 352.18 -0.6544 3.22 3.069 5 1 54.56 4 5 26 0
TCMC1999 C21H24N2O3 Rauwolfia Serpentina 352.18 -0.6544 3.22 3.069 5 1 54.56 4 5 26 0
TCMC2051 C10H8O4 Scopoletin 192.04 -0.2421 2.12 1.088 1 1 55.76 3 2 14 0
TCMC2204 C9H6O3 Umbelliferone 162.03 -0.1903 2.12 1.532 1 1 46.53 1 2 12 0
TCMC2550 C15H24 (+)-Germacrene D 204.19 2.7967 3.11 6.294 0 0 0 4 1 15 1

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1. General Information of the Component  
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3. Putative Targets  
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