Component: Zanthoxylum echinocarpum 单面针


Description of the Component

Component ID
TCMH403
Latin Name
Zanthoxylum echinocarpum
English Name
NA
Chinese Pinyin Name
Dan Mian Zhen
中文名
单面针
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx542 Fu Ke Qian Jin Capsule 妇科千金胶囊
TCMFx541 Fu Ke Qian Jin Tablet 妇科千金片
TCMFx3894 Fu Ke Qian Jin Tablets 妇科千金片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT208 MAOA Monoamine oxidase A Oxidoreductase P21397
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT268 CYP2A13 Cytochrome P450 2A13 Oxidoreductase Q16696
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1112 Quinolone resistance protein norA
TCMT1218 Staphylococcus aureus
TCMT1349 Helicobacter pylori SS1

Ingredient Structrues

Ingredient ID: TCMC787
Formula: C12H8O4

Ingredient ID: TCMC2101
Formula: C12H8O4

Ingredient ID: TCMC1897
Formula: C13H10O5

Ingredient ID: TCMC1858
Formula: C16H14O4

Ingredient ID: TCMC1777
Formula: C8H18O

Ingredient ID: TCMC1551
Formula: C12H8O4

Ingredient ID: TCMC1404
Formula: C13H10O5

Ingredient ID: TCMC1382
Formula: C12H8O4

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC787 C12H8O4 Bergapten 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0
TCMC1382 C12H8O4 Isobergaptene 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0
TCMC1404 C13H10O5 Isopimpinellin 246.05 0.0123 2.34 1.246 1 0 57.9 4 3 18 0
TCMC1551 C12H8O4 Methoxsalen 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0
TCMC1777 C8H18O Octanol 130.14 -2.1254 2.23 3.127 1 1 20.23 8 0 9 0
TCMC1858 C16H14O4 Pentosalen 270.09 1.5296 2.78 2.891 1 0 48.67 5 3 20 0
TCMC1897 C13H10O5 Pimpinellin 246.05 0.0123 2.34 1.246 1 0 57.9 4 3 18 0
TCMC2101 C12H8O4 Sphondin 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)