Component: Areca catechu 大腹子


Description of the Component

Component ID
TCMH358
Latin Name
Areca catechu
English Name
Areca palm
Chinese Pinyin Name
Da Fu Zi
中文名
大腹子
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
ITSAA732-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2827 Shi Pi Powder 实脾散

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT22 ALPI Intestinal alkaline phosphatase Hydrolase P09923
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT267 GABRR1 GABA receptor rho-1 subunit Ion channel P24046
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT289 TBXAS1 Thromboxane-A synthase Isomerase P24557
TCMT290 CHRM5 Muscarinic acetylcholine receptor M5 GPCR P08912
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT47 BCL2 Apoptosis regulator Bcl-2 Ion channel P10415
TCMT551 CHRM4 Muscarinic acetylcholine receptor M4 GPCR P08173
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT60 FASN Fatty acid synthase Unclassified P49327
TCMT601 F2 Thrombin Unclassified P00734
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1109 Reverse transcriptase
TCMT1175 Human immunodeficiency virus
TCMT1178 Actinomyces viscosus
TCMT1189 Pseudomonas fluorescens
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1226 Klebsiella pneumoniae
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1438 Plasmodium falciparum
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC913
Formula: C15H14O6

Ingredient ID: TCMC912
Formula: C15H10O4

Ingredient ID: TCMC878
Formula: C15H14O6

Ingredient ID: TCMC720
Formula: C8H13NO2.BrH

Ingredient ID: TCMC719
Formula: C8H13NO2

Ingredient ID: TCMC415
Formula: C22H18O11

Ingredient ID: TCMC34
Formula: C10H14N2

Ingredient ID: TCMC3
Formula: C15H14O6

Ingredient ID: TCMC2808
Formula: C30H26O12

Ingredient ID: TCMC2580
Formula: C30H26O12

Ingredient ID: TCMC24
Formula: C15H14O6

Ingredient ID: TCMC2124
Formula: C76H52O46

Ingredient ID: TCMC2119
Formula: C9H10O5

Ingredient ID: TCMC1889
Formula: C16H12O5

Ingredient ID: TCMC1733
Formula: C28H32O16

Ingredient ID: TCMC1564
Formula: C7H7NO2

Ingredient ID: TCMC1512
Formula: C9H11NO2

Ingredient ID: TCMC1394
Formula: C6H9NO2.ClH

Ingredient ID: TCMC1393
Formula: C6H9NO2

Ingredient ID: TCMC1301
Formula: C6H9NO2.ClH

Ingredient ID: TCMC1300
Formula: C6H9NO2

Ingredient ID: TCMC13
Formula: C15H14O6

Ingredient ID: TCMC1204
Formula: C15H14O7

Ingredient ID: TCMC1202
Formula: C7H6O5

Ingredient ID: TCMC1101
Formula: C11H12O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC3 C15H14O6 (-)-Catechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC13 C15H14O6 (-)-Epicatechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC24 C15H14O6 (+)-Epicatechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC34 C10H14N2 (+/-)Nicotine 162.12 -0.4993 2.34 1.485 2 0 16.13 2 2 12 0
TCMC415 C22H18O11 3,4,5-Trihydroxy-Benzoic Acid (2R,3S)-5,7-Dihydroxy-2-(3,4,5-Trihydroxy-Phenyl)-Chroman-3-Yl Ester 458.08 -3.966 2.67 0.694 2 8 197.37 12 4 33 1
TCMC719 C8H13NO2 Arecoline 155.09 0.1341 2.01 0.172 3 0 29.54 4 1 11 0
TCMC720 C8H13NO2.BrH Arecoline Hydrobromide 155.09 0.1341 2.01 0.172 3 0 29.54 4 1 11 0
TCMC878 C15H14O6 Catechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC912 C15H10O4 Chrysophanol 254.06 -0.8062 2.67 1.627 2 2 74.6 3 3 19 0
TCMC913 C15H14O6 Cianidanol 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC1101 C11H12O3 Elemicin 192.08 0.6742 2.34 2.486 0 0 27.69 4 2 14 0
TCMC1202 C7H6O5 Gallic Acid 170.02 -1.6207 1.68 0.002 2 4 97.99 5 1 12 0
TCMC1204 C15H14O7 Gallocatechin 306.07 -2.9543 2.34 -0.128 1 6 130.61 7 3 22 1
TCMC1300 C6H9NO2 Guvacine 127.06 -0.6528 1.79 0.041 3 2 49.33 2 1 9 0
TCMC1301 C6H9NO2.ClH Guvacine Hydrochloride 127.06 -0.6528 1.79 0.041 3 2 49.33 2 1 9 0
TCMC1393 C6H9NO2 Isoguvacine 127.06 -0.1092 1.79 -0.388 3 2 49.33 2 1 9 0
TCMC1394 C6H9NO2.ClH Isoguvacine Hydrochloride 127.06 -0.1092 1.79 -0.388 3 2 49.33 2 1 9 0
TCMC1512 C9H11NO2 L-Phenylalanine 165.08 -1.0844 2.12 0.441 3 2 63.32 5 1 12 0
TCMC1564 C7H7NO2 Methyl Nicotinate 137.05 0.0112 1.9 0.958 3 0 39.19 3 1 10 0
TCMC1733 C28H32O16 Narcissin 624.17 -5.7305 2.78 -1.098 11 9 254.52 18 5 44 2
TCMC1889 C16H12O5 Physcion 284.07 -0.858 2.67 1.183 2 2 83.83 5 3 21 0
TCMC2119 C9H10O5 Syringic Acid 198.05 -0.8037 1.9 0.182 2 2 75.99 7 1 14 0
TCMC2124 C76H52O46 Tannic Acid 1700.17 -12.6304 4.76 2.662 16 25 777.98 56 11 122 3
TCMC2580 C30H26O12 Procyanidin B2 578.14 -5.1813 3.44 0.165 2 10 220.76 13 6 42 1
TCMC2808 C30H26O12 Procyanidin B3 578.14 -5.1813 3.44 0.165 2 10 220.76 13 6 42 1

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