Component: Pterocarpus indicus 紫檀


Description of the Component

Component ID
TCMH2726
Latin Name
Pterocarpus indicus
English Name
Burmacoast padauk
Chinese Pinyin Name
Zi Tan
中文名
紫檀
TCM Properties
Warm,Pungent
TCM Meridians
Lung,Spleen,Stomach
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAA3130-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF1326 Bawei Qingxin Chenxiang Powder 八味清心沉香散
TCMF2087 Bawei Qingxin Chenxiang Powder 八味清心沉香散

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT212 SRC Tyrosine-protein kinase SRC Kinase P12931
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT237 SLC5A1 Sodium/glucose cotransporter 1 Transporter P13866
TCMT238 SLC5A2 Sodium/glucose cotransporter 2 Transporter P31639
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT289 TBXAS1 Thromboxane-A synthase Isomerase P24557
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT344 AOX1 Aldehyde oxidase Oxidoreductase Q06278
TCMT359 FYN Tyrosine-protein kinase FYN Kinase P06241
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT567 DNMT1 DNA (cytosine-5)-methyltransferase 1 Transferase P26358
TCMT591 ESRRA Estrogen-related receptor alpha Nuclear receptor P11474
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT613 NR3C1 Glucocorticoid receptor Nuclear receptor P04150
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT714 ODC1 Ornithine decarboxylase Lyase P11926
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT910 ESRRB Estrogen-related receptor beta Nuclear receptor O95718
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1092 Fatty acid synthase
TCMT1099 Neuraminidase
TCMT1104 Sortase
TCMT1170 Enterobacter cloacae
TCMT1176 Streptococcus pneumoniae
TCMT1213 Neisseria gonorrhoeae
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC984
Formula: C21H20O9

Ingredient ID: TCMC845
Formula: C15H24O

Ingredient ID: TCMC699
Formula: C16H16O4

Ingredient ID: TCMC407
Formula: C15H10O6

Ingredient ID: TCMC394
Formula: C2H5NO3

Ingredient ID: TCMC274
Formula: C6H14O

Ingredient ID: TCMC2564
Formula: C16H16O3

Ingredient ID: TCMC228
Formula: C6H14O2

Ingredient ID: TCMC1963
Formula: C17H14O5

Ingredient ID: TCMC1530
Formula: C6H6O3

Ingredient ID: TCMC1236
Formula: C15H10O5

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC228 C6H14O2 1,1-Diethoxyethane 118.1 0.8705 1.9 1.273 2 0 18.46 7 0 8 0
TCMC274 C6H14O 1-Hexanol 102.1 -1.5494 2.01 1.989 1 1 20.23 6 0 7 0
TCMC394 C2H5NO3 2-Nitroethanol 91.03 -0.0012 1.24 -0.527 1 1 63.37 4 0 6 0
TCMC407 C15H10O6 3-(2,4-Dihydroxyphenyl)-5,7-Dihydroxychromen-4-One 286.05 -2.5079 2.45 0.549 1 4 107.22 5 3 21 0
TCMC699 C16H16O4 Angolensin 272.1 -0.9414 2.78 2.755 1 2 66.76 8 2 20 0
TCMC845 C15H24O Butylated Hydroxytoluene 220.18 3.2941 3 5.957 0 1 20.23 10 1 16 1
TCMC984 C21H20O9 Daidzin 416.11 -3.3342 2.78 1.367 6 5 145.91 9 4 30 0
TCMC995 C35H60O6 Daucosterol 576.44 -0.4469 4.65 10.487 6 4 99.38 19 5 41 1
TCMC1236 C15H10O5 Genistein 270.05 -2.0476 2.56 1.512 1 3 86.99 4 3 20 0
TCMC1530 C6H6O3 Maltol 126.03 -0.6804 1.79 0.907 3 1 46.53 2 1 9 0
TCMC1963 C17H14O5 Pterocarpin 298.08 -1.0076 2.78 2.316 0 0 46.15 2 5 22 0
TCMC2564 C16H16O3 (Z)-4-(3,5-Dimethoxystyryl)Phenol 256.11 -0.0961 2.89 4.474 0 1 38.69 7 2 19 0

Download Data

All data can be downloaded by:

   → Selecting data type in the below download table
   → Then click the download button.
Data Section
Select to Download
1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)