Component: Ventilago leiocarpa 血风藤


Description of the Component

Component ID
TCMH2347
Latin Name
Ventilago leiocarpa
English Name
NA
Chinese Pinyin Name
Xue Feng Teng
中文名
血风藤
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3555 Fu Fang Hai She Ding 复方海蛇酊
TCMFx4063 Kang Feng Shi Oral Liquid 抗风湿液

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT714 ODC1 Ornithine decarboxylase Lyase P11926
TCMT752 CSNK2A1 Casein kinase II alpha Kinase P68400
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1176 Streptococcus pneumoniae
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1214 Enterococcus faecium
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1286 Bacillus cereus
TCMT1294 Human parainfluenza virus 3
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC912
Formula: C15H10O4

Ingredient ID: TCMC499
Formula: C20H18O4

Ingredient ID: TCMC2819
Formula: C20H20O3

Ingredient ID: TCMC2704
Formula: C30H18O10

Ingredient ID: TCMC255
Formula: C15H12O4

Ingredient ID: TCMC2438
Formula: C15H10O6

Ingredient ID: TCMC2129
Formula: C30H50O

Ingredient ID: TCMC2107
Formula: C29H48O

Ingredient ID: TCMC1889
Formula: C16H12O5

Ingredient ID: TCMC1515
Formula: C30H50O

Ingredient ID: TCMC1105
Formula: C15H10O5

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC255 C15H12O4 1,8-Dihydroxy-3-Methyl-4A,9A-Dihydroanthracene-9,10-Dione 256.07 -0.4584 2.67 0.487 3 2 74.6 3 3 19 0
TCMC499 C20H18O4 4-Hydroxyloncarpin 322.12 0.0845 3.22 4.164 1 2 66.76 7 3 24 0
TCMC912 C15H10O4 Chrysophanol 254.06 -0.8062 2.67 1.627 2 2 74.6 3 3 19 0
TCMC1105 C15H10O5 Emodin 270.05 -1.2665 2.56 0.664 2 3 94.83 4 3 20 0
TCMC1515 C30H50O Lupeol 426.39 3.2313 4.65 11.901 1 1 20.23 9 5 31 1
TCMC1889 C16H12O5 Physcion 284.07 -0.858 2.67 1.183 2 2 83.83 5 3 21 0
TCMC2107 C29H48O Stigmasterol 412.37 1.2566 4.54 11.071 1 1 20.23 12 4 30 1
TCMC2129 C30H50O Taraxerol 426.39 3.4636 4.65 11.352 1 1 20.23 9 5 31 1
TCMC2438 C15H10O6 Catenarin 286.05 -1.7268 2.45 -0.51 2 4 115.06 5 3 21 0
TCMC2704 C30H18O10 Skyrin 538.09 -2.533 3.66 0.496 4 6 189.66 9 6 40 1
TCMC2819 C20H20O3 Isocordoin 308.14 1.0541 3.33 6.252 1 2 57.53 9 2 23 1

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1. General Information of the Component  
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3. Putative Targets  
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