Component: Clematis chinensis 威灵


Description of the Component

Component ID
TCMH2164
Latin Name
Clematis chinensis
English Name
Chinese clematis
Chinese Pinyin Name
Wei Ling
中文名
威灵
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF7072 Jin Wu Gu Tong Capsules 金乌骨通胶囊

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT38 DRD2 Dopamine D2 receptor GPCR P14416
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT565 EP300 Histone acetyltransferase p300 Transferase Q09472
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT678 XIAP Inhibitor of apoptosis protein 3 Transferase P98170
TCMT679 MPEG1 Macrophage-expressed gene 1 protein Unclassified Q2M385
TCMT680 KAT2B Histone acetyltransferase PCAF Transferase Q92831
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1104 Sortase
TCMT1178 Actinomyces viscosus
TCMT1209 Staphylococcus haemolyticus
TCMT1210 Streptococcus sobrinus
TCMT1211 Fusobacterium nucleatum
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1245 Phytophthora cactorum
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1321 Staphylococcus hominis
TCMT1343 Staphylococcus simulans
TCMT1344 Staphylococcus sciuri
TCMT1361 Neisseria meningitidis
TCMT1370 Prevotella melaninogenica
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1408 Colletotrichum gloeosporioides
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC999
Formula: C10H20O2

Ingredient ID: TCMC995
Formula: C35H60O6

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC696
Formula: C10H12O

Ingredient ID: TCMC553
Formula: C6H6O3

Ingredient ID: TCMC463
Formula: C14H12N2S

Ingredient ID: TCMC2694
Formula: C20H24O6

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC2222
Formula: C8H8O4

Ingredient ID: TCMC2166
Formula: C10H14O

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1777
Formula: C8H18O

Ingredient ID: TCMC1751
Formula: C9H20

Ingredient ID: TCMC1578
Formula: C11H14O2

Ingredient ID: TCMC1495
Formula: C18H32O2

Ingredient ID: TCMC1493
Formula: C10H18O

Ingredient ID: TCMC1192
Formula: C30H50O

Ingredient ID: TCMC1104
Formula: C17H26O4

Ingredient ID: TCMC1101
Formula: C11H12O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC463 C14H12N2S 4-(1,3-Benzothiazol-2-Yl)-2-Methylaniline 240.07 0.4827 2.67 3.571 2 1 67.15 3 3 17 0
TCMC553 C6H6O3 5-Hydroxymethyl-Furfural 126.03 -0.7952 1.79 0.422 2 1 50.44 3 1 9 0
TCMC696 C10H12O Anethole 148.09 0.8555 2.45 3.979 0 0 9.23 4 1 11 0
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC995 C35H60O6 Daucosterol 576.44 -0.4469 4.65 10.487 6 4 99.38 19 5 41 1
TCMC999 C10H20O2 Decanoic Acid 172.15 -2.1697 2.34 4.156 2 1 37.3 10 0 12 0
TCMC1101 C11H12O3 Elemicin 192.08 0.6742 2.34 2.486 0 0 27.69 4 2 14 0
TCMC1104 C17H26O4 Embelin 294.18 -3.4988 2.89 6.234 4 2 74.6 13 1 21 1
TCMC1192 C30H50O Friedeline 426.39 3.2175 4.65 12.613 1 0 17.07 8 5 31 1
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1495 C18H32O2 Linoleic Acid 280.24 -0.9485 3.22 7.865 2 1 37.3 16 0 20 2
TCMC1578 C11H14O2 Methyleugenol 178.1 0.9251 2.45 3.003 0 0 18.46 6 1 13 0
TCMC1751 C9H20 Nonane 128.16 -1.9134 2.45 5.461 0 0 0 8 0 9 1
TCMC1777 C8H18O Octanol 130.14 -2.1254 2.23 3.127 1 1 20.23 8 0 9 0
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC2166 C10H14O Thymol 150.1 0.7546 2.45 3.556 0 1 20.23 5 1 11 0
TCMC2222 C8H8O4 Vanillic Acid 168.04 -0.7519 1.9 0.626 2 2 66.76 5 1 12 0
TCMC2541 C10H18O Alpha-Terpineol 154.14 1.1223 2.45 2.369 1 1 20.23 5 1 11 0
TCMC2694 C20H24O6 Isolariciresinol 360.16 -2.2141 3 1.061 2 4 99.38 11 3 26 0

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