TCM-ID Component

Description of the Component

Component ID	TCMH2147
Latin Name	Radix rehmanniae
English Name	Fresh rehmannia root
Chinese Pinyin Name	Tu Sheng Di
中文名	土生地
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx4131	Gui Long Yao Ointment	桂龙药膏
TCMFx4138	Gui Long Yao Wine	桂龙药酒

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT133	CA1	Carbonic anhydrase I	Lyase	P00915
TCMT134	CA2	Carbonic anhydrase II	Lyase	P00918
TCMT135	CA14	Carbonic anhydrase XIV	Lyase	Q9ULX7
TCMT136	CA12	Carbonic anhydrase XII	Lyase	O43570
TCMT137	CA9	Carbonic anhydrase IX	Lyase	Q16790
TCMT138	CA7	Carbonic anhydrase VII	Lyase	P43166
TCMT189	DUSP3	Dual specificity protein phosphatase 3	Hydrolase	P51452
TCMT267	GABRR1	GABA receptor rho-1 subunit	Ion channel	P24046
TCMT27	DRD1	Dopamine D1 receptor	GPCR	P21728
TCMT306	MMP2	Matrix metalloproteinase-2	Hydrolase	P08253
TCMT320	MMP3	Matrix metalloproteinase 3	Hydrolase	P08254
TCMT321	MMP9	Matrix metalloproteinase 9	Hydrolase	P14780
TCMT322	MMP13	Matrix metalloproteinase 13	Hydrolase	P45452
TCMT42	KMT2A	Histone-lysine N-methyltransferase MLL	Transferase	Q03164
TCMT619	HSP90AA1	Heat shock protein HSP 90-alpha	Unclassified	P07900
TCMT632	PNP	Purine nucleoside phosphorylase	Transferase	P00491
TCMT69	THRB	Thyroid hormone receptor beta-1	Nuclear receptor	P10828
TCMT734	MMP12	Matrix metalloproteinase 12	Hydrolase	P39900

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC1566
Formula: C10H10O3

Common Name	Methyl P-Hydroxycinnamate
IUPAC Name	methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
Canonical SMILES	COC(=O)/C=C/c1ccc(cc1)O
Standard InCHI	InChI=1S/C10H10O3/c1-13-10(12)7-4-8-2-5-9(11)6-3-8/h2-7,11H,1H3/b7-4+
Standard InCHIKey	NITWSHWHQAQBAW-QPJJXVBHSA-N
External Identifiers	ChEMBL [CHEMBL146816]; PubChem [5319562];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH600	Euonymus fortunei	Fu Fang Teng	扶芳藤
TCMH271	Clerodendrum trichotomum	Chou Wu Tong Ye	臭梧桐叶
TCMH2513	Rhododendron mucronulatum	Ying Shan Hong	映山红
TCMH213	Boschniakia rossica	Cao Cong Rong	草苁蓉
TCMH2207	Schisandra sphenanthera	Wu Xiang Xue Teng	五香血藤
TCMH2147	Radix rehmanniae	Tu Sheng Di	土生地
TCMH1896	Radix rehmanniae	Sheng Di Huang	生地黄
TCMH1897	Radix rehmanniae	Sheng Di Huang Zhi	生地黄汁
TCMH270	Clerodendrum trichotomum	Chou Wu Tong	臭梧桐

Ingredient ID: TCMC1378
Formula: C29H36O15

Common Name	Isoacteoside
IUPAC Name	[(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Canonical SMILES	O=C(OC[C@H]1O[C@@H](OCCc2ccc(c(c2)O)O)[C@@H]([C@H]([C@@H]1O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)O)/C=C/c1ccc(c(c1)O)O
Standard InCHI	InChI=1S/C29H36O15/c1-13-22(35)24(37)25(38)29(42-13)44-27-23(36)20(12-41-21(34)7-4-14-2-5-16(30)18(32)10-14)43-28(26(27)39)40-9-8-15-3-6-17(31)19(33)11-15/h2-7,10-11,13,20,22-33,35-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27-,28+,29-/m0/s1
Standard InCHIKey	FNMHEHXNBNCPCI-QEOJJFGVSA-N
External Identifiers	ChEMBL [CHEMBL504873]; PubChem [6476333];
Reference of Component-Ingredient Pair	28616865

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH241	Plantago asiatica	Che Qian Zi	车前子
TCMH1740	Cistanche deserticola	Rou Cong Rong	肉苁蓉
TCMH2137	Pogostemon cablin	Tu Huo Xiang	土藿香
TCMH1894	Pinellia ternata	Sheng Ban Xia	生半夏
TCMH387	Callicarpa macrophylla	Da Ye Zi Zhu	大叶紫珠
TCMH240	Plantago depressa	Che Qian Cao	车前草
TCMH1966	Rehmannia glutinosa	Shu Di Huang	熟地黄
TCMH1285	Orobanche coerulescens	Lie Dang	列当
TCMH2147	Radix rehmanniae	Tu Sheng Di	土生地
TCMH203	Acorus calamus	Cang Chang Pu	藏菖蒲
TCMH1896	Radix rehmanniae	Sheng Di Huang	生地黄
TCMH1897	Radix rehmanniae	Sheng Di Huang Zhi	生地黄汁
TCMH130	Pinellia ternata	Ban Xia	半夏
TCMH131	Pinellia ternata	Ban Xia Qu	半夏曲
TCMH1677	Pinellia ternata	Qing Ban Xia	清半夏
TCMH519	Pogostemon cablin	Du Huo Xiang	杜藿香
TCMH728	Pogostemon cablin	Guang Huo Xiang	广藿香
TCMH1008	Pogostemon cablin	Huo Xiang	藿香
TCMH1009	Pogostemon cablin	Huo Xiang Ye	藿香叶
TCMH8	Rehmannia glutinosa	Ai Di Huang	矮地黄
TCMH451	Rehmannia glutinosa	Di Huang	地黄
TCMH453	Rehmannia glutinosa	Di Huang Tan	地黄炭
TCMH643	Rehmannia glutinosa	Gan Di Huang	干地黄

Ingredient ID: TCMC1298
Formula: C10H13N5O5

Common Name	Guanosine
IUPAC Name	2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Canonical SMILES	OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1[nH]c(=N)nc2O
Standard InCHI	InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
Standard InCHIKey	NYHBQMYGNKIUIF-UUOKFMHZSA-N
External Identifiers	ChEMBL [CHEMBL375655]; PubChem [6802];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH611	Rubus idaeus	Fu Pen Zi	覆盆子
TCMH1626	Fritillaria ussuriensis	Ping Bei Mu	平贝母
TCMH2469	Fritillaria pallidiflora	Yi Bei Mu	伊贝母
TCMH865	Carthamus tinctorius	Hong Hua	红花
TCMH2703	Fritillaria unibracteata	Zi Bei Mu	紫贝母
TCMH274	Fritillaria cirrhosa	Chuan Bei Mu Liu Jin Gao	川贝母流浸膏
TCMH2137	Pogostemon cablin	Tu Huo Xiang	土藿香
TCMH985	Astragalus membranaceus	Huang Qi Ti Qu Ye	黄芪提取液
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1894	Pinellia ternata	Sheng Ban Xia	生半夏
TCMH1299	Ganoderma lucidum	Ling Zhi(1)	灵芝
TCMH422	Angelica sinensis	Dang Gui Gan Jin Gao	当归干浸膏
TCMH1839	Panax ginseng	Shan Shen	山参
TCMH2090	Gastrodia elata	Tian Ma	天麻
TCMH388	Ziziphus jujuba	Da Zao	大枣
TCMH1197	Selaginella tamariscina	Juan Bai	卷柏
TCMH2261	Fritillaria thunbergii	Xiang Bei	象贝
TCMH1966	Rehmannia glutinosa	Shu Di Huang	熟地黄
TCMH970	Vitex negundo	Huang Jing Zi	黄荆子
TCMH2147	Radix rehmanniae	Tu Sheng Di	土生地
TCMH1428	Ophiopogon japonicus	Mai Men Dong	麦门冬
TCMH1714	Lonicera japonica	Ren Dong Teng	忍冬藤
TCMH2059	Radix pseudostellariae	Tai Zi Shen	太子参
TCMH1777	Panax notoginseng	San Qi Ye Jing	三七叶茎
TCMH273	Fritillaria cirrhosa	Chuan Bei Mu	川贝母
TCMH1127	Lonicera japonica	Jin Yin Hua	金银花
TCMH1128	Lonicera japonica	Jin Yin Hua Ti Qu Ye	金银花提取液
TCMH421	Angelica sinensis	Dang Gui	当归
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH1896	Radix rehmanniae	Sheng Di Huang	生地黄
TCMH1897	Radix rehmanniae	Sheng Di Huang Zhi	生地黄汁
TCMH130	Pinellia ternata	Ban Xia	半夏
TCMH131	Pinellia ternata	Ban Xia Qu	半夏曲
TCMH1677	Pinellia ternata	Qing Ban Xia	清半夏
TCMH1770	Panax notoginseng	San Qi Gan Jin Gao	三七干浸膏
TCMH1771	Panax notoginseng	San Qi Gao Fen	三七膏粉
TCMH1772	Panax notoginseng	San Qi Hua	三七花
TCMH1774	Panax notoginseng	San Qi Jing Ye	三七茎叶
TCMH1776	Panax notoginseng	San Qi Ye	三七叶
TCMH981	Astragalus membranaceus	Huang Qi	黄芪
TCMH983	Astragalus membranaceus	Huang Qi Gan Jin Gao	黄芪干浸膏
TCMH984	Astragalus membranaceus	Huang Qi Jin Gao	黄芪浸膏
TCMH1296	Ganoderma lucidum	Ling Zhi Jin Gao	灵芝浸膏
TCMH1721	Panax ginseng	Ren Shen	人参
TCMH1728	Panax ginseng	Ren Shen Ye	人参叶
TCMH519	Pogostemon cablin	Du Huo Xiang	杜藿香
TCMH728	Pogostemon cablin	Guang Huo Xiang	广藿香
TCMH1008	Pogostemon cablin	Huo Xiang	藿香
TCMH1009	Pogostemon cablin	Huo Xiang Ye	藿香叶
TCMH8	Rehmannia glutinosa	Ai Di Huang	矮地黄
TCMH451	Rehmannia glutinosa	Di Huang	地黄
TCMH453	Rehmannia glutinosa	Di Huang Tan	地黄炭
TCMH643	Rehmannia glutinosa	Gan Di Huang	干地黄
TCMH1423	Ophiopogon japonicus	Mai Dong	麦冬
TCMH1424	Ophiopogon japonicus	Mai Dong Men	麦冬门
TCMH1425	Ophiopogon japonicus	Mai Dong Rou	麦冬肉

Ingredient ID: TCMC1209
Formula: C4H9NO2

Common Name	Gamma-Aminobutyric Acid
IUPAC Name	4-aminobutanoic acid
Canonical SMILES	NCCCC(=O)O
Standard InCHI	InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
Standard InCHIKey	BTCSSZJGUNDROE-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL96]; PubChem [119];
Reference of Component-Ingredient Pair	29968805

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2407	Bupleurum chinense	Yan Tai Chai Hu	烟台柴胡
TCMH641	Bufo melanostictus	Gan Chan	干蟾
TCMH1186	Lycium chinense	Gou Qi Zi	枸杞子
TCMH552	Rhizoma pinelliae preparata	Fa Ban Xia	法半夏
TCMH1343	Aloe vera	Lu Hui	芦荟
TCMH1923	Acorus tatarinowii	Shi Chang Pu Qing Gao	石菖蒲清膏
TCMH2710	Homo sapiens	Zi He Che	紫河车
TCMH1894	Pinellia ternata	Sheng Ban Xia	生半夏
TCMH2221	Citrullus vulgaris	Xi Gua	西瓜
TCMH517	Angelica pubescens	Du Huo	独活
TCMH422	Angelica sinensis	Dang Gui Gan Jin Gao	当归干浸膏
TCMH1999	Bubalus bubalis	Shui Niu Jiao Nong Suo Fen	水牛角浓缩粉
TCMH1966	Rehmannia glutinosa	Shu Di Huang	熟地黄
TCMH1665	Notopterygium incisum	Qiang Huo	羌活
TCMH1798	Morus alba	Sang Zhi	桑枝
TCMH2086	Trichosanthes kirilowii	Tian Hua Fen	天花粉
TCMH2147	Radix rehmanniae	Tu Sheng Di	土生地
TCMH665	Saccharum sinensis	Gan Zhe	甘蔗
TCMH943	Rhizoma dioscoreae	Huai Shan Yao	淮山药
TCMH1512	Isatis indigotica	Mu Da Qing Ye	木大青叶
TCMH421	Angelica sinensis	Dang Gui	当归
TCMH1575	Bubalus bubalis	Niu Jiao Fen	牛角粉
TCMH1576	Bubalus bubalis	Niu Jiao Jian Fen	牛角尖粉
TCMH1577	Bubalus bubalis	Niu Jiao Tan	牛角炭
TCMH1997	Bubalus bubalis	Shui Niu Jiao	水牛角
TCMH1998	Bubalus bubalis	Shui Niu Jiao Gan Jin Gao	水牛角干浸膏
TCMH1185	Lycium chinense	Gou Qi	枸杞
TCMH1734	Homo sapiens	Ren Zhong Bai	人中白
TCMH1896	Radix rehmanniae	Sheng Di Huang	生地黄
TCMH1897	Radix rehmanniae	Sheng Di Huang Zhi	生地黄汁
TCMH130	Pinellia ternata	Ban Xia	半夏
TCMH131	Pinellia ternata	Ban Xia Qu	半夏曲
TCMH1677	Pinellia ternata	Qing Ban Xia	清半夏
TCMH705	Trichosanthes kirilowii	Gua Lou	瓜蒌
TCMH706	Trichosanthes kirilowii	Gua Lou Pi	瓜蒌皮
TCMH707	Trichosanthes kirilowii	Gua Lou Ren	瓜蒌仁
TCMH708	Trichosanthes kirilowii	Gua Lou Ren Shuang	瓜蒌仁霜
TCMH709	Trichosanthes kirilowii	Gua Lou Shi	栝蒌实
TCMH711	Trichosanthes kirilowii	Gua Lou Gen	栝楼根
TCMH712	Trichosanthes kirilowii	Gua Lou Ren(1)	栝楼仁
TCMH279	Angelica pubescens	Chuan Du Huo	川独活
TCMH1792	Morus alba	Sang Pi	桑皮
TCMH1797	Morus alba	Sang Ye	桑叶
TCMH228	Bupleurum chinense	Chai Hu	柴胡
TCMH229	Bupleurum chinense	Chai Hu Jin Gao	柴胡浸膏
TCMH230	Bupleurum chinense	Chai Hu Shao	柴胡梢
TCMH292	Notopterygium incisum	Chuan Qiang Huo	川羌活
TCMH126	Isatis indigotica	Ban Lan	板蓝
TCMH127	Isatis indigotica	Ban Lan Gen	板蓝根
TCMH381	Isatis indigotica	Da Qing Ye	大青叶
TCMH1510	Isatis indigotica	Mu Ban Lan Gen	木板蓝根
TCMH232	Bufo melanostictus	Chan Chu	蟾蜍
TCMH8	Rehmannia glutinosa	Ai Di Huang	矮地黄
TCMH451	Rehmannia glutinosa	Di Huang	地黄
TCMH453	Rehmannia glutinosa	Di Huang Tan	地黄炭
TCMH643	Rehmannia glutinosa	Gan Di Huang	干地黄
TCMH1920	Acorus tatarinowii	Shi Chang Pu	石菖蒲
TCMH1922	Acorus tatarinowii	Shi Chang Pu Jin Gao	石菖蒲浸膏

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC1209	C4H9NO2	Gamma-Aminobutyric Acid	103.06	-1.2313	1.57	-0.668	3	2	63.32	5	0	7	0
TCMC1298	C10H13N5O5	Guanosine	283.09	-2.2152	1.46	-1.643	10	6	156.21	6	3	20	1
TCMC1378	C29H36O15	Isoacteoside	624.21	-4.2978	3	-0.202	11	9	245.29	21	4	44	3
TCMC1566	C10H10O3	Methyl P-Hydroxycinnamate	178.06	-0.088	2.23	2.207	2	1	46.53	5	1	13	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Radix rehmanniae 土生地

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC1566

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1378

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1298

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1209

Occurrence of the ingredient across TCM components

Properties

Download Data