Component: Chloranthus holostegius 四块瓦


Description of the Component

Component ID
TCMH2023
Latin Name
Chloranthus holostegius
English Name
Fortune chloranthus herb
Chinese Pinyin Name
Si Kuai Wa
中文名
四块瓦
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
GBVI1215-11
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx5121 San Qi Yao Wine 三七药酒
TCMFx5293 Wai Yong Wu Di Ointment 外用无敌膏
TCMFx901 Zuan Shan Feng Syrup 钻山风糖浆
TCMFx6851 Zuan Shan Feng Syrup 钻山风糖浆

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT100 TTR Transthyretin Unclassified P02766
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT340 GLRA1 Glycine receptor subunit alpha-1 Ion channel P23415
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1438 Plasmodium falciparum
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC2588
Formula: C28H30O10

Ingredient ID: TCMC1888
Formula: C28H30O10

Ingredient ID: TCMC1767
Formula: C18H19NO4

Ingredient ID: TCMC1719
Formula: C27H43NO2

Ingredient ID: TCMC1271
Formula: C2H5NO2

Ingredient ID: TCMC1145
Formula: C11H12O4

Ingredient ID: TCMC1072
Formula: C27H42O3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC1072 C27H42O3 Disogenin 414.31 0.2771 4.1 6.041 3 1 38.69 5 6 30 1
TCMC1145 C11H12O4 Ethyl Caffeate 208.07 -0.2979 2.23 1.885 2 2 66.76 7 1 15 0
TCMC1271 C2H5NO2 Glycine 75.03 -1.1915 1.35 -3.35 3 2 63.32 3 0 5 0
TCMC1719 C27H43NO2 413.33 0.0108 4.1 5.845 3 2 41.49 5 6 30 1
TCMC1767 C18H19NO4 N-Trans-Feruloyl Tyramine 313.13 -0.6499 2.89 3.109 2 3 82.28 10 2 23 0
TCMC1888 C28H30O10 Physalin F 526.18 -1.2344 3.44 -0.4 10 1 137.96 4 9 38 0
TCMC2588 C28H30O10 Physalin G 526.18 -1.0459 3.44 -0.618 10 2 145.66 5 8 38 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)