Component: Geum japonicum 水杨梅


Description of the Component

Component ID
TCMH2005
Latin Name
Geum japonicum
English Name
Japanese avens
Chinese Pinyin Name
Shui Yang Mei
中文名
水杨梅
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3697 Gan Mao An Tablets 感冒安片
TCMFx5777 Shui Yang Mei Tablets 水杨梅片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT102 ACP1 Low molecular weight phosphotyrosine protein phosphatase Hydrolase P24666
TCMT103 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) Hydrolase P10586
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT233 PTPN11 Protein-tyrosine phosphatase 2C Hydrolase Q06124
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT640 CTSD Cathepsin D Unclassified P07339


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1107 Protease
TCMT1218 Staphylococcus aureus
TCMT1229 Enterococcus faecalis
TCMT1255 Human immunodeficiency virus 1
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC801
Formula: C29H50O

Ingredient ID: TCMC2613
Formula: C30H48O5

Ingredient ID: TCMC2490
Formula: C23H20O6

Ingredient ID: TCMC2459
Formula: C30H48O5

Ingredient ID: TCMC2216
Formula: C30H48O3

Ingredient ID: TCMC1537
Formula: C30H48O4

Ingredient ID: TCMC1123
Formula: C15H12O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC801 C29H50O Beta-Sitosterol 414.39 1.3 4.54 11.595 1 1 20.23 13 4 30 1
TCMC1123 C15H12O6 Eriodictyol 288.06 -2.2747 2.45 0.363 1 4 107.22 5 3 21 0
TCMC1537 C30H48O4 Maslinic Acid 472.36 1.9071 4.32 8.24 4 3 77.76 11 5 34 1
TCMC2216 C30H48O3 Ursolic Acid 456.36 1.4838 4.43 8.954 3 2 57.53 10 5 33 1
TCMC2459 C30H48O5 Euscaphic Acid 488.35 0.822 4.21 5.966 5 4 97.99 12 5 35 1
TCMC2490 C23H20O6 Dehydrodeguelin 392.13 0.0692 3.33 3.204 1 0 63.22 6 5 29 0
TCMC2613 C30H48O5 Tomentic Acid 488.35 0.822 4.21 5.966 5 4 97.99 12 5 35 1

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)