Component: Tacca plantaginea 水三七


Description of the Component

Component ID
TCMH2000
Latin Name
Tacca plantaginea
English Name
NA
Chinese Pinyin Name
Shui San Qi
中文名
水三七
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
ITSAN589-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx6448 Zhi Ke Ding Chuan Tablets 止咳定喘片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT613 NR3C1 Glucocorticoid receptor Nuclear receptor P04150
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1180 Human herpesvirus 2
TCMT1213 Neisseria gonorrhoeae
TCMT1247 Human herpesvirus 1
TCMT1250 Vesicular stomatitis virus
TCMT1294 Human parainfluenza virus 3
TCMT1438 Plasmodium falciparum
TCMT1447 Respiratory syncytial virus
TCMT1449 Influenza A virus
TCMT1450 Plasmodium falciparum 3D7
TCMT1451 Sclerotinia
TCMT1452 Rhizopus microsporus var. chinensis
TCMT1453 Penicillium crustosum

Ingredient Structrues

Ingredient ID: TCMC737
Formula: C21H20O11

Ingredient ID: TCMC2330
Formula: C22H22O7

Ingredient ID: TCMC1923
Formula: C15H22O2

Ingredient ID: TCMC1919
Formula: C22H22O8

Ingredient ID: TCMC1912
Formula: C25H32O11

Ingredient ID: TCMC1911
Formula: C31H44O15

Ingredient ID: TCMC1910
Formula: C31H42O15

Ingredient ID: TCMC109
Formula: C25H34O9

Ingredient ID: TCMC108
Formula: C25H34O11

Ingredient ID: TCMC107
Formula: C25H34O10

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC107 C25H34O10 (3R,5R)-3,5-Dihydroxy-1-(3,4-Dihydroxyphenyl)-7-(4-Hydroxyphenyl)-Heptane 3-O-Beta-D-Glucopyranoside 494.22 -4.8884 3.11 1.849 7 8 180.3 19 3 35 2
TCMC108 C25H34O11 (3R,5R)-3,5-Dihydroxy-1,7-Bis(3,4-Dihydroxyphenyl)Heptane3-O-Beta-D-Glucopyranoside 510.21 -5.3487 3 1.104 7 9 200.53 20 3 36 2
TCMC109 C25H34O9 (3R,5R)-3,5-Dihydroxy-1,7-Bis(4-Hydroxyphenyl)Heptane 3-O-Beta-D-Glucopyranoside 478.22 -4.4281 3.22 2.594 7 7 160.07 18 3 34 2
TCMC737 C21H20O11 Astragalin 448.1 -4.4318 2.56 0.18 7 7 186.37 11 4 32 1
TCMC1910 C31H42O15 Plantagineoside A 654.25 -5.9804 3.22 0.181 11 10 256.29 24 4 46 3
TCMC1911 C31H44O15 Plantagineoside B 656.27 -6.8729 3.22 0.59 11 11 259.45 25 4 46 3
TCMC1912 C25H32O11 Plantagineoside C 508.19 -5.1553 3 1.092 7 8 189.53 15 4 36 1
TCMC1919 C22H22O8 Podofilox 414.13 -1.5006 3 1.259 3 1 92.68 8 5 30 0
TCMC1923 C15H22O2 Polygodial 234.16 0.6974 2.89 4.485 2 0 34.14 5 2 17 0
TCMC2330 C22H22O7 Desoxypodophyllotoxin 398.14 -0.6687 3.11 2.289 2 0 72.45 7 5 29 0

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1. General Information of the Component  
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3. Putative Targets  
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