TCM-ID Component

Description of the Component

Component ID	TCMH1485
Latin Name	Aglaia odorata
English Name
Chinese Pinyin Name	Mi Lan Hua
中文名	米兰花
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	CFDA
Barcode ID	ITSAD3994-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx5791	Run Hou Yao Tea	润喉药茶

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT130	ALOX5	Arachidonate 5-lipoxygenase	Oxidoreductase	P09917
TCMT193	RELA	Nuclear factor NF-kappa-B p65 subunit	Transcription factor	Q04206
TCMT295	MMP1	Matrix metalloproteinase-1	Hydrolase	P03956
TCMT306	MMP2	Matrix metalloproteinase-2	Hydrolase	P08253
TCMT320	MMP3	Matrix metalloproteinase 3	Hydrolase	P08254
TCMT321	MMP9	Matrix metalloproteinase 9	Hydrolase	P14780
TCMT6	NFKB1	Nuclear factor NF-kappa-B p105 subunit	Transcription factor	P19838

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1438	Plasmodium falciparum
TCMT1455	Mycobacterium tuberculosis H37Rv
TCMT1465	Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC640
Formula: C28H28O8

Common Name	Aglafolin
IUPAC Name	methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Canonical SMILES	COc1ccc(cc1)[C@]12Oc3c([C@]2(O)[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)OC)O)c(OC)cc(c3)OC
Standard InCHI	InChI=1S/C28H28O8/c1-32-18-12-10-17(11-13-18)28-23(16-8-6-5-7-9-16)22(26(30)35-4)25(29)27(28,31)24-20(34-3)14-19(33-2)15-21(24)36-28/h5-15,22-23,25,29,31H,1-4H3/t22-,23-,25-,27+,28+/m1/s1
Standard InCHIKey	VFTGDXPPYSWBSO-GWNOIRNCSA-N
External Identifiers	ChEMBL [CHEMBL394528]; PubChem [393601];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花

Ingredient ID: TCMC2637
Formula: C35H34N2O5

Common Name	Cocsuline
IUPAC Name	n.a.
Canonical SMILES	COc1cc2CCN([C@@H]3c2c2c1Oc1cc4CCN([C@H](c4cc1O2)Cc1ccc(c(Oc2ccc(C3)cc2)c1)O)C)C
Standard InCHI	InChI=1S/C35H34N2O5/c1-36-12-10-22-17-30-31-19-25(22)26(36)15-21-6-9-28(38)29(16-21)40-24-7-4-20(5-8-24)14-27-33-23(11-13-37(27)2)18-32(39-3)34(41-30)35(33)42-31/h4-9,16-19,26-27,38H,10-15H2,1-3H3/t26-,27-/m0/s1
Standard InCHIKey	GOYCVNCWKXBQBF-SVBPBHIXSA-N
External Identifiers	ChEMBL [CHEMBL447886]; PubChem [21579625];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花

Ingredient ID: TCMC2584
Formula: C35H34N2O5

Common Name	Trilobine
IUPAC Name	n.a.
Canonical SMILES	COc1ccc2cc1Oc1ccc(cc1)C[C@@H]1NCCc3c1c1Oc4cc5[C@H](C2)N(C)CCc5cc4Oc1c(c3)OC
Standard InCHI	InChI=1S/C35H34N2O5/c1-37-13-11-22-17-30-31-19-25(22)27(37)15-21-6-9-28(38-2)29(16-21)40-24-7-4-20(5-8-24)14-26-33-23(10-12-36-26)18-32(39-3)34(41-30)35(33)42-31/h4-9,16-19,26-27,36H,10-15H2,1-3H3/t26-,27-/m0/s1
Standard InCHIKey	XZAXGQMTBGFTFE-SVBPBHIXSA-N
External Identifiers	ChEMBL [CHEMBL500324]; PubChem [169007];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花
TCMH2267	Periploca sepium	Xiang Jia Pi	香加皮

Ingredient ID: TCMC2565
Formula: C20H25NO4

Common Name	Laudanidine
IUPAC Name	5-[[(1S)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-methoxyphenol
Canonical SMILES	COc1ccc(cc1O)C[C@@H]1N(C)CCc2c1cc(OC)c(c2)OC
Standard InCHI	InChI=1S/C20H25NO4/c1-21-8-7-14-11-19(24-3)20(25-4)12-15(14)16(21)9-13-5-6-18(23-2)17(22)10-13/h5-6,10-12,16,22H,7-9H2,1-4H3/t16-/m0/s1
Standard InCHIKey	MPYHGNAJOKCMAQ-INIZCTEOSA-N
External Identifiers	ChEMBL [CHEMBL251625]; PubChem [821396];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2515	Papaver somniferum	Ying Su Ke	罂粟壳
TCMH1658	Euphorbia lathyris	Qian Jin Zi	千金子
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花
TCMH1489	Papaver somniferum	Mi Ying Su Ke	蜜罂粟壳
TCMH2514	Papaver somniferum	Ying Su	罂粟

Ingredient ID: TCMC2489
Formula: C18H21NO3

Common Name	(1S)-N-Methyl-Coclaurine
IUPAC Name	(1S)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Canonical SMILES	COc1cc2CCN([C@H](c2cc1O)Cc1ccc(cc1)O)C
Standard InCHI	InChI=1S/C18H21NO3/c1-19-8-7-13-10-18(22-2)17(21)11-15(13)16(19)9-12-3-5-14(20)6-4-12/h3-6,10-11,16,20-21H,7-9H2,1-2H3/t16-/m0/s1
Standard InCHIKey	BOKVLBSSPUTWLV-INIZCTEOSA-N
External Identifiers	ChEMBL [CHEMBL513109]; PubChem [440584];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1601	Nelumbo nucifera	Ou Pian	藕片
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花
TCMH814	Nelumbo nucifera	He Geng	荷梗
TCMH825	Nelumbo nucifera	He Ye	荷叶
TCMH1275	Nelumbo nucifera	Lian Zi	莲子
TCMH1276	Nelumbo nucifera	Lian Zi Xin	莲子心
TCMH1598	Nelumbo nucifera	Ou	藕
TCMH1599	Nelumbo nucifera	Ou Fen	藕粉

Ingredient ID: TCMC2444
Formula: C19H23NO4

Common Name	(S)-Reticuline
IUPAC Name	(1S)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Canonical SMILES	COc1ccc(cc1O)C[C@@H]1N(C)CCc2c1cc(O)c(c2)OC
Standard InCHI	InChI=1S/C19H23NO4/c1-20-7-6-13-10-19(24-3)17(22)11-14(13)15(20)8-12-4-5-18(23-2)16(21)9-12/h4-5,9-11,15,21-22H,6-8H2,1-3H3/t15-/m0/s1
Standard InCHIKey	BHLYRWXGMIUIHG-HNNXBMFYSA-N
External Identifiers	ChEMBL [CHEMBL235212]; PubChem [439653];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1416	Thalictrum foliolosum	Ma Wei Lian	马尾连
TCMH2515	Papaver somniferum	Ying Su Ke	罂粟壳
TCMH2589	Cinnamomum camphora	Zhang Shu Zi	樟树子
TCMH1102	Tinospora capillipes	Jin Guo Lan	金果榄
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花
TCMH2584	Cinnamomum camphora	Zhang Mu	樟木
TCMH2585	Cinnamomum camphora	Zhang Nao	樟脑
TCMH2587	Cinnamomum camphora	Zhang Nao Zi	樟脑子
TCMH2588	Cinnamomum camphora	Zhang Shu Gen	樟树根
TCMH1489	Papaver somniferum	Mi Ying Su Ke	蜜罂粟壳
TCMH2514	Papaver somniferum	Ying Su	罂粟

Ingredient ID: TCMC2340
Formula: C20H23NO4

Common Name	O-Methylflavinantine
IUPAC Name	n.a.
Canonical SMILES	COC1=C[C@@]23CCN([C@@H](C2=CC1=O)Cc1c3cc(OC)c(c1)OC)C
Standard InCHI	InChI=1S/C20H23NO4/c1-21-6-5-20-11-19(25-4)16(22)9-14(20)15(21)7-12-8-17(23-2)18(24-3)10-13(12)20/h8-11,15H,5-7H2,1-4H3/t15-,20-/m1/s1
Standard InCHIKey	DBPGJIUVRZHFCM-FOIQADDNSA-N
External Identifiers	ChEMBL [CHEMBL490139]; PubChem [11724883];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花

Ingredient ID: TCMC2023
Formula: C26H26O6

Common Name	Rocaglaol
IUPAC Name	(1R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-1,8b-diol
Canonical SMILES	COc1ccc(cc1)[C@]12Oc3c([C@]2(O)[C@@H](C[C@H]1c1ccccc1)O)c(OC)cc(c3)OC
Standard InCHI	InChI=1S/C26H26O6/c1-29-18-11-9-17(10-12-18)26-20(16-7-5-4-6-8-16)15-23(27)25(26,28)24-21(31-3)13-19(30-2)14-22(24)32-26/h4-14,20,23,27-28H,15H2,1-3H3/t20-,23+,25+,26-/m0/s1
Standard InCHIKey	RRVZOJQBRVGMMK-HCBGRYSISA-N
External Identifiers	ChEMBL [CHEMBL468454]; PubChem [393602];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花

Ingredient ID: TCMC2022
Formula: C29H31NO7

Common Name	Rocaglamide
IUPAC Name	(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
Canonical SMILES	COc1ccc(cc1)[C@]12Oc3c([C@]2(O)[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)N(C)C)O)c(OC)cc(c3)OC
Standard InCHI	InChI=1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,33H,1-5H3/t23-,24-,26-,28+,29+/m1/s1
Standard InCHIKey	DAPAQENNNINUPW-IDAMAFBJSA-N
External Identifiers	ChEMBL [CHEMBL438139]; PubChem [331783];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花

Ingredient ID: TCMC1783
Formula: C18H24N2O2

Common Name	Odorine
IUPAC Name	(2S)-2-methyl-N-[(2R)-1-[(E)-3-phenylprop-2-enoyl]pyrrolidin-2-yl]butanamide
Canonical SMILES	CC[C@@H](C(=N[C@H]1CCCN1C(=O)/C=C/c1ccccc1)O)C
Standard InCHI	InChI=1S/C18H24N2O2/c1-3-14(2)18(22)19-16-10-7-13-20(16)17(21)12-11-15-8-5-4-6-9-15/h4-6,8-9,11-12,14,16H,3,7,10,13H2,1-2H3,(H,19,22)/b12-11+/t14-,16+/m0/s1
Standard InCHIKey	KZAOEMMZRGEBST-IXVOVUJJSA-N
External Identifiers	ChEMBL [CHEMBL521297]; PubChem [23242585];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1485	Aglaia odorata	Mi Lan Hua	米兰花

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC640	C28H28O8	Aglafolin	492.18	-2.1147	3.66	5.396	4	2	103.68	13	5	36	1
TCMC1783	C18H24N2O2	Odorine	300.18	-1.2845	3	5.615	4	1	52.9	9	2	22	1
TCMC2022	C29H31NO7	Rocaglamide	505.21	-2.5561	3.77	5.007	4	2	97.69	14	5	37	1
TCMC2023	C26H26O6	Rocaglaol	434.17	-1.629	3.66	5.594	2	2	77.38	10	5	32	1
TCMC2340	C20H23NO4	O-Methylflavinantine	341.16	-0.2078	3.11	1.802	3	0	48	7	4	25	0
TCMC2444	C19H23NO4	(S)-Reticuline	329.16	-0.6295	3	2.031	1	2	62.16	9	3	24	0
TCMC2489	C18H21NO3	(1S)-N-Methyl-Coclaurine	299.15	-0.5777	3	2.475	1	2	52.93	7	3	22	0
TCMC2565	C20H25NO4	Laudanidine	343.18	-0.221	3.11	2.55	1	1	51.16	10	3	25	0
TCMC2584	C35H34N2O5	Trilobine	562.25	-0.3124	4.54	5.839	2	1	61.42	5	7	42	1
TCMC2637	C35H34N2O5	Cocsuline	562.25	-0.185	4.54	5.559	2	1	63.63	5	7	42	1

Download Data

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Aglaia odorata 米兰花

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC640

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2637

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2584

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2565

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2489

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2444

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2340

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2023

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2022

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1783

Occurrence of the ingredient across TCM components

Properties

Download Data