Component: Fructus terminaliae billericae 毛诃子


Description of the Component

Component ID
TCMH1457
Latin Name
Fructus terminaliae billericae
English Name
friot of belleric terminalia
Chinese Pinyin Name
Mao He Zi
中文名
毛诃子
TCM Properties
Mild,Sweet,Punkery
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
remove toxic heat, arrest discharges, nourish blood, and coordinate the actions of various ingredients in a prescription
Toxicity
NA
Geo-authentic habitats (道地产区)
Tibet
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx7083 Bai Xuan Xia Ta Re Capsules 百癣夏塔热胶囊
TCMFx1314 Cuitang Pills 催汤丸
TCMFx2026 Cuitang Pills 催汤丸
TCMF2625 Ershiwuwei Zhenzhu Pills 二十五味珍珠丸
TCMF1445 Ershiwuwei Zhenzhu Pills 二十五味珍珠丸
TCMFx1922 Renqing Mangjue Pills 仁青芒觉
TCMFx1290 Renqing Mangjue Pills 仁青芒觉

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT191 STAT3 Signal transducer and activator of transcription 3 Transcription factor P40763
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT286 KLF5 Kruppel-like factor 5 Unclassified Q13887
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1109 Reverse transcriptase
TCMT1218 Staphylococcus aureus
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani

Ingredient Structrues

Ingredient ID: TCMC2800
Formula: C19H20O3

Ingredient ID: TCMC2261
Formula: C18H18O2

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1804
Formula: C29H44O12

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1804 C29H44O12 Ouabain 584.28 -4.1486 3.33 -0.808 12 8 206.6 14 6 41 2
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC2261 C18H18O2 Anolignan B 266.13 1.0156 3.22 5.446 0 2 40.46 7 2 20 1
TCMC2800 C19H20O3 Termilignan 296.14 0.9638 3.22 4.58 0 2 49.69 9 2 22 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)