Component: Trachelospermum jasminoides 络石藤


Description of the Component

Component ID
TCMH1376
Latin Name
Trachelospermum jasminoides
English Name
Chinese star jasmine
Chinese Pinyin Name
Luo Shi Teng
中文名
络石藤
TCM Properties
Minor cold,Bitter
TCM Meridians
Liver,Heart
Therapeutic Class English
For dispelling wind-dampness
Therapeutic Class Chinese
祛风湿
Functions
dispel wind and remove obstruction from the channels and remove heat from blood and cause subsidence of swelling
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAJ4261-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx3556 Feng Shi Zhi Tong Yao Wine 风湿止痛药酒
TCMFx2405 Five Insect and Four Vine Decoction 五虫四藤汤
TCMF3522 Gu Tong Yao Wine 骨痛药酒
TCMF2199 Pain Releasing Decoction 定痛汤
TCMFx4456 Pan Long Qi Tablets 盘龙七片
TCMFx4463 Pan Long Qi Yao Wine 盘龙七药酒
TCMF5147 Qu Feng Shi Gu Tong Wine 祛风湿骨痛酒
TCMFx1193 She Xiang Kang Shuan Capsule 麝香抗栓胶囊
TCMFx5171 She Xiang Kang Shuan Pills 麝香抗栓丸
TCMFx5358 Shen Nong Yao Wine 神农药酒
TCMFx5433 Shen Zhou Die Da Pills 神州跌打丸
TCMFx5416 Shu Jin Huo Xue Tablets 舒筋活血片
TCMFx2237 Tablet for Relieving Rigidity of Muscles and Promoting Blood Circulation 舒筋活血片
TCMFx6216 Zhong Feng Hui Chun Pills 中风回春丸
TCMFx326 Zhong Feng Hui Chun Pills 中风回春丸
TCMFx327 Zhong Feng Hui Chun Tablet 中风回春片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT127 PARP1 Poly [ADP-ribose] polymerase-1 Transferase P09874
TCMT128 TNKS2 Tankyrase-2 Transferase Q9H2K2
TCMT129 TNKS Tankyrase-1 Transferase O95271
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT195 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Kinase Q02750
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT212 SRC Tyrosine-protein kinase SRC Kinase P12931
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT217 CYP2C8 Cytochrome P450 2C8 Oxidoreductase P10632
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT22 ALPI Intestinal alkaline phosphatase Hydrolase P09923
TCMT220 CYP2J2 Cytochrome P450 2J2 Oxidoreductase P51589
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT23 ALPL Alkaline phosphatase, tissue-nonspecific isozyme Hydrolase P05186
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT295 MMP1 Matrix metalloproteinase-1 Hydrolase P03956
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT331 PLG Plasminogen Unclassified P00747
TCMT335 MPO Myeloperoxidase Oxidoreductase P05164
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT36 HTR1A Serotonin 1a (5-HT1a) receptor GPCR P08908
TCMT369 IGF1R Insulin-like growth factor I receptor Kinase P08069
TCMT370 KDR Vascular endothelial growth factor receptor 2 Kinase P35968
TCMT374 AURKB Serine/threonine-protein kinase Aurora-B Kinase Q96GD4
TCMT377 INSR Insulin receptor Kinase P06213
TCMT388 AXL Tyrosine-protein kinase receptor UFO Kinase P30530
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT402 ALK ALK tyrosine kinase receptor Kinase Q9UM73
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT422 CAMK2B CaM kinase II beta Kinase Q13554
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT436 NUAK1 NUAK family SNF1-like kinase 1 Kinase O60285
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT441 PTK2 Focal adhesion kinase 1 Kinase Q05397
TCMT445 NEK2 Serine/threonine-protein kinase NEK2 Kinase P51955
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT460 MAPKAPK2 MAP kinase-activated protein kinase 2 Kinase P49137
TCMT462 NEK6 Serine/threonine-protein kinase NEK6 Kinase Q9HC98
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT484 PLK1 Serine/threonine-protein kinase PLK1 Kinase P53350
TCMT507 MAPK14 MAP kinase p38 alpha Kinase Q16539
TCMT508 SYK Tyrosine-protein kinase SYK Kinase P43405
TCMT510 KIT Stem cell growth factor receptor Kinase P10721
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT601 F2 Thrombin Unclassified P00734
TCMT629 ABCC1 Multidrug resistance-associated protein 1 Transporter P33527
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT734 MMP12 Matrix metalloproteinase 12 Hydrolase P39900
TCMT739 GPR35 G-protein coupled receptor 35 GPCR Q9HC97
TCMT740 PIK3CG PI3-kinase p110-gamma subunit Transferase P48736
TCMT747 ABCG2 ATP-binding cassette sub-family G member 2 Transporter Q9UNQ0
TCMT752 CSNK2A1 Casein kinase II alpha Kinase P68400
TCMT784 AVPR2 Vasopressin V2 receptor GPCR P30518
TCMT785 CXCR1 Interleukin-8 receptor A GPCR P25024
TCMT786 CCR4 C-C chemokine receptor type 4 GPCR P51679
TCMT791 PKN1 Protein kinase N1 Kinase Q16512
TCMT793 PYGL Liver glycogen phosphorylase Transferase P06737
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT822 FUT7 Alpha-(1,3)-fucosyltransferase 7 Transferase Q11130
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1092 Fatty acid synthase
TCMT1093 Enoyl-acyl-carrier protein reductase
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1108 Integrase
TCMT1109 Reverse transcriptase
TCMT1121 Sialidase
TCMT1136 Neuraminidase
TCMT1178 Actinomyces viscosus
TCMT1208 Escherichia coli K12
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1230 Human herpesvirus 5
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1286 Bacillus cereus
TCMT1294 Human parainfluenza virus 3
TCMT1346 Helicobacter pylori
TCMT1349 Helicobacter pylori SS1
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1412 Salmonella typhimurium
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1443 Leishmania amazonensis
TCMT1447 Respiratory syncytial virus
TCMT1449 Influenza A virus
TCMT1450 Plasmodium falciparum 3D7
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC847
Formula: C9H8O4

Ingredient ID: TCMC789
Formula: C14H16O9

Ingredient ID: TCMC76
Formula: C15H12O7

Ingredient ID: TCMC718
Formula: C21H24O6

Ingredient ID: TCMC710
Formula: C15H10O5

Ingredient ID: TCMC66
Formula: C15H12O7

Ingredient ID: TCMC6508
Formula: C33H44O17

Ingredient ID: TCMC6077
Formula: C27H30O16

Ingredient ID: TCMC5912
Formula: C21H26N2O3

Ingredient ID: TCMC5495
Formula: C27H30O15

Ingredient ID: TCMC4696
Formula: C21H20O11

Ingredient ID: TCMC4383
Formula: C27H30O14

Ingredient ID: TCMC4329
Formula: C18H20N2

Ingredient ID: TCMC4324
Formula: C29H48O

Ingredient ID: TCMC3985
Formula: C26H32O11

Ingredient ID: TCMC3981
Formula: C20H22O7

Ingredient ID: TCMC3966
Formula: C29H50O

Ingredient ID: TCMC3964
Formula: C19H24N2O

Ingredient ID: TCMC3963
Formula: C21H27NO7

Ingredient ID: TCMC3962
Formula: C21H24O7

Ingredient ID: TCMC3764
Formula: C20H22O7

Ingredient ID: TCMC3652
Formula: C28H48O

Ingredient ID: TCMC3642
Formula: C27H34O12

Ingredient ID: TCMC3375
Formula: C27H34O11

Ingredient ID: TCMC3254
Formula: C21H26N2O2

Ingredient ID: TCMC30
Formula: C15H12O7

Ingredient ID: TCMC2137
Formula: C15H12O7

Ingredient ID: TCMC1982
Formula: C15H10O7

Ingredient ID: TCMC182
Formula: C9H8O4

Ingredient ID: TCMC1538
Formula: C20H22O6

Ingredient ID: TCMC1409
Formula: C21H20O12

Ingredient ID: TCMC1206
Formula: C21H20O11

Ingredient ID: TCMC1202
Formula: C7H6O5

Ingredient ID: TCMC113
Formula: C21H24O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC30 C15H12O7 (+)-Taxifolin 304.06 -2.9269 2.34 0.028 2 5 127.45 6 3 22 0
TCMC66 C15H12O7 (2R)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One 304.06 -2.9269 2.34 0.028 2 5 127.45 6 3 22 0
TCMC76 C15H12O7 (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-2,3-Dihydrochromen-4-One 304.06 -2.9269 2.34 0.028 2 5 127.45 6 3 22 0
TCMC113 C21H24O6 (3S,4S)-4-[(3,4-Dimethoxyphenyl)Methyl]-3-[(4-Hydroxy-3-Methoxyphenyl)Methyl]Oxolan-2-One 372.16 -0.5036 3.11 2.934 2 1 74.22 11 3 27 0
TCMC182 C9H8O4 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC710 C15H10O5 Apigenin 270.05 -1.8845 2.56 1.567 1 3 86.99 4 3 20 0
TCMC718 C21H24O6 Arctigenin 372.16 -0.5036 3.11 2.934 2 1 74.22 11 3 27 0
TCMC789 C14H16O9 Bergenin 328.08 -2.8389 2.01 -2.021 6 5 145.91 8 3 23 0
TCMC847 C9H8O4 Caffeic Acid 180.04 -0.7993 2.01 1.141 2 3 77.76 5 1 13 0
TCMC1202 C7H6O5 Gallic Acid 170.02 -1.6207 1.68 0.002 2 4 97.99 5 1 12 0
TCMC1206 C21H20O11 Galuteolin 448.1 -4.0917 2.56 -0.075 6 7 186.37 11 4 32 1
TCMC1409 C21H20O12 Isoquercetin 464.1 -4.8921 2.45 -0.354 7 8 206.6 12 4 33 1
TCMC1538 C20H22O6 Matairesinol 358.14 -0.9121 3 2.415 2 2 85.22 10 3 26 0
TCMC1982 C15H10O7 Quercetin 302.04 -2.8012 2.34 1.381 2 5 127.45 6 3 22 0
TCMC2137 C15H12O7 Taxifolin 304.06 -2.9269 2.34 0.028 2 5 127.45 6 3 22 0
TCMC3254 C21H26N2O2 Coronaridine 339.2072531 -2.4598 3.33 3.782 3 2 46.53 3 3 25 0
TCMC3375 C27H34O11 Arctiin 534.2101119 -2.2505 3.22 1.826 7 4 153.37 10 4 38 0
TCMC3642 C27H34O12 Tracheloside 550.2050265 -2.851 3.11 1.308 8 5 173.6 10 4 39 0
TCMC3652 C28H48O Campesterol 400.3705162 1.9762 4.43 11.026 1 1 20.23 5 4 29 1
TCMC3764 C20H22O7 Wikstromol 374.136553 -1.5126 2.89 1.897 3 3 105.45 6 3 27 0
TCMC3962 C21H24O7 Trachelogenin 388.1522031 -1.1041 3 2.416 3 2 94.45 7 3 28 0
TCMC3963 C21H27NO7 Trachelogenin Amide 405.1787522 -2.1081 2.89 0.439 4 4 131.47 10 2 29 0
TCMC3964 C19H24N2O Conoflorine 297.1966884 -1.5737 3.22 3.431 2 2 32.76 1 5 22 0
TCMC3966 C29H50O Sitosterol,Β-Sitosterol 414.3861662 1.3 4.54 11.595 1 1 20.23 6 4 30 1
TCMC3981 C20H22O7 D-Nortrachelogenin 374.136553 -1.5126 2.89 1.897 3 3 105.45 6 3 27 0
TCMC3985 C26H32O11 Matairesinoside 520.1944618 -2.659 3.11 1.307 7 5 164.37 9 4 37 0
TCMC4324 C29H48O Stigmasterol 412.3705162 1.2566 4.54 11.071 1 1 20.23 5 4 30 1
TCMC4329 C18H20N2 Apparicine 265.1704737 -1.0248 3.22 2.752 1 2 20.23 0 3 20 0
TCMC4383 C27H30O14 Apigenin-7-O-Neohesperidoside 578.1635556 -4.6859 2.89 -0.792 13 8 215.83 6 5 41 2
TCMC4696 C21H20O11 Luteolin-4'-O-Glucoside 448.1005615 -3.7247 2.56 -0.945 6 7 177.14 4 4 32 1
TCMC5495 C27H30O15 Apigenin-7-O-Gentiobioside 594.1584703 -5.0113 2.78 -1.519 11 9 236.06 7 5 42 2
TCMC5912 C21H26N2O3 Tabernaemontanine 355.2021677 -2.9498 3.22 3.144 4 2 63.6 3 4 26 0
TCMC6077 C27H30O16 Luteolin-7-O-Gentiobioside 610.1533849 -5.6462 2.67 -2.029 14 10 256.29 7 5 43 2
TCMC6508 C33H44O17 Trachelogenin 4'-O-Β-Gentiobioside 712.2578499 -4.5979 3.22 -0.229 13 8 252.75 13 5 50 3

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1. General Information of the Component  
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3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)