Component: Stellera chamaejasme 狼毒


Description of the Component

Component ID
TCMH1245
Latin Name
Stellera chamaejasme
English Name
Chinese stellera
Chinese Pinyin Name
Lang Du
中文名
狼毒
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
Anhui Province, Heilongjiang Province
Reference
CFDA
Barcode ID
ITSAB3705-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx4656 Jie He Ling Tablets 结核灵片
TCMFx5174 Qu Feng Shi Zhi Tong Powder 祛风湿止痛散
TCMFx6259 You Fu Ning Capsules 优福宁胶囊

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1438 Plasmodium falciparum

Ingredient Structrues

Ingredient ID: TCMC991
Formula: C9H6O4

Ingredient ID: TCMC85
Formula: C32H26O10

Ingredient ID: TCMC744
Formula: C19H18O8

Ingredient ID: TCMC7294
Formula: C33H28O10

Ingredient ID: TCMC6914
Formula: C32H26O10

Ingredient ID: TCMC6537
Formula: C32H26O10

Ingredient ID: TCMC6505
Formula: C31H24O10

Ingredient ID: TCMC6252
Formula: C33H28O10

Ingredient ID: TCMC5985
Formula: C30H22O10

Ingredient ID: TCMC5776
Formula: C32H26O10

Ingredient ID: TCMC5680
Formula: C30H22O10

Ingredient ID: TCMC5649
Formula: C32H26O10

Ingredient ID: TCMC5570
Formula: C35H52O9

Ingredient ID: TCMC5512
Formula: C31H24O10

Ingredient ID: TCMC5306
Formula: C20H24O12

Ingredient ID: TCMC4803
Formula: C30H22O10

Ingredient ID: TCMC4651
Formula: C20H14O7

Ingredient ID: TCMC4468
Formula: C9H10O

Ingredient ID: TCMC3794
Formula: C33H28O10

Ingredient ID: TCMC3417
Formula: C30H44O8

Ingredient ID: TCMC3056
Formula: C13H28

Ingredient ID: TCMC2965
Formula: C12H26

Ingredient ID: TCMC2611
Formula: C30H22O10

Ingredient ID: TCMC2204
Formula: C9H6O3

Ingredient ID: TCMC2101
Formula: C12H8O4

Ingredient ID: TCMC1899
Formula: C20H22O6

Ingredient ID: TCMC1897
Formula: C13H10O5

Ingredient ID: TCMC1404
Formula: C13H10O5

Ingredient ID: TCMC1382
Formula: C12H8O4

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC85 C32H26O10 (2S)-3-[(2S,3S)-5,7-Dihydroxy-2-(4-Methoxyphenyl)-4-Oxo-2,3-Dihydrochromen-3-Yl]-5,7-Dihydroxy-2-(4-Methoxyphenyl)-2,3-Dihydrochromen-4-One 570.15 -3.1708 3.88 2.362 2 4 151.98 11 6 42 0
TCMC744 C19H18O8 Atranorin 374.1 0.2728 2.67 4.034 4 3 130.36 13 2 27 0
TCMC991 C9H6O4 Daphnetin 178.03 -0.6506 2.01 0.998 1 2 66.76 2 2 13 0
TCMC1382 C12H8O4 Isobergaptene 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0
TCMC1404 C13H10O5 Isopimpinellin 246.05 0.0123 2.34 1.246 1 0 57.9 4 3 18 0
TCMC1897 C13H10O5 Pimpinellin 246.05 0.0123 2.34 1.246 1 0 57.9 4 3 18 0
TCMC1899 C20H22O6 Pinoresinol 358.14 -2.0222 3 1.684 2 2 77.38 8 4 26 0
TCMC2101 C12H8O4 Sphondin 216.04 0.0641 2.34 1.69 1 0 48.67 2 3 16 0
TCMC2204 C9H6O3 Umbelliferone 162.03 -0.1903 2.12 1.532 1 1 46.53 1 2 12 0
TCMC2611 C30H22O10 Rel-Isochamaejasmin 542.12 -3.9878 3.66 1.324 2 6 173.98 9 6 40 1
TCMC2965 C12H26 Dodecane 170.2034508 -2.7774 2.78 7.168 0 0 0 9 0 12 1
TCMC3056 C13H28 N-Tridecane 184.2191009 -3.0654 2.89 7.737 0 0 0 10 0 13 1
TCMC3417 C30H44O8 Simplexin 532.3036184 -3.0801 3.88 4.013 8 3 117.98 10 6 38 0
TCMC3794 C33H28O10 Ruixianglangdusu B 584.1682471 -2.7623 3.99 2.881 2 3 140.98 6 6 43 0
TCMC4468 C9H10O Cinnamic Alcohol 134.0731649 0.0191 2.34 3.808 1 1 20.23 2 1 10 0
TCMC4651 C20H14O7 Daphnoretin Methyl Ether 366.0739528 0.0778 2.89 5.062 2 0 61.83 4 4 27 1
TCMC4803 C30H22O10 Neochamaejasmenin A 542.1212969 -3.9878 3.66 1.324 2 6 173.98 3 6 40 1
TCMC5306 C20H24O12 O-[Β-D-Xylopyranosyl(1→6) Β-D-Glucopyranosyl] 7-Hydroxycoumarin 456.1267762 -3.1056 2.34 -0.346 10 6 175.37 5 4 32 1
TCMC5512 C31H24O10 7-Methoxylneochaejasmin A 556.136947 -3.5793 3.77 1.843 2 5 162.98 4 6 41 0
TCMC5570 C35H52O9 Pentadecadienoic Acid 616.3611332 -3.3344 4.32 5.073 9 5 157.05 15 4 44 2
TCMC5649 C32H26O10 Chamaejasmenin D 570.152597 -3.1708 3.88 2.362 2 4 151.98 5 6 42 0
TCMC5680 C30H22O10 (+)-Chamaejasmin 542.1212969 -3.9878 3.66 1.324 2 6 173.98 3 6 40 1
TCMC5776 C32H26O10 Isochamaejasmenin B 570.152597 -3.1708 3.88 2.362 2 4 151.98 5 6 42 0
TCMC5985 C30H22O10 Isoneochamaejasmin A 542.1212969 -3.9878 3.66 1.324 2 6 173.98 3 6 40 1
TCMC6252 C33H28O10 Ruixianglangdusu A 584.1682471 -2.7623 3.99 2.881 2 3 140.98 6 6 43 0
TCMC6505 C31H24O10 Sikokianin A 556.136947 -3.5793 3.77 1.843 2 5 162.98 4 6 41 0
TCMC6537 C32H26O10 Chamaejasmenin B 570.152597 -3.1708 3.88 2.362 2 4 151.98 5 6 42 0
TCMC6914 C32H26O10 Chamaejasmenin A 570.152597 -3.1708 3.88 2.362 2 4 151.98 5 6 42 0
TCMC7294 C33H28O10 Chamaejasmenin C 584.1682471 -2.7623 3.99 2.881 2 3 140.98 6 6 43 0

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