Drug Information

Drug ID:  NPD4359
Drug Name:  Permethrin
Molecular Formula:  C21H20Cl2O3
Canonical SMILES:  ClC(=CC1C(C1(C)C)C(=O)OCc1cccc(c1)Oc1ccccc1)Cl
Standard InCHI:  InChI=1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3
Standard InCHIKey:  RLLPVAHGXHCWKJ-UHFFFAOYSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  ChEMBL

  Structural Similarity Between NPASS Natural Products and NPD4359

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
High Similarity 1.0 NPC320287
High Similarity 0.9569 NPC234956
Intermediate Similarity 0.8047 NPC476332
Intermediate Similarity 0.8047 NPC473464
Intermediate Similarity 0.8031 NPC322569
Intermediate Similarity 0.8 NPC170749
Intermediate Similarity 0.7937 NPC159916
Intermediate Similarity 0.7899 NPC473855
Intermediate Similarity 0.7899 NPC473393
Intermediate Similarity 0.7886 NPC280760
Intermediate Similarity 0.7879 NPC223807
Intermediate Similarity 0.7874 NPC98748
Intermediate Similarity 0.7846 NPC279379
Intermediate Similarity 0.7846 NPC470887
Intermediate Similarity 0.784 NPC51345
Intermediate Similarity 0.7836 NPC475102
Intermediate Similarity 0.7803 NPC128321
Intermediate Similarity 0.7795 NPC293424
Intermediate Similarity 0.7769 NPC157473
Intermediate Similarity 0.7769 NPC151530
Intermediate Similarity 0.776 NPC87563
Intermediate Similarity 0.7687 NPC176590
Intermediate Similarity 0.7686 NPC326447
Intermediate Similarity 0.7686 NPC176971
Intermediate Similarity 0.7669 NPC329272
Intermediate Similarity 0.7667 NPC283546
Intermediate Similarity 0.7656 NPC277460
Intermediate Similarity 0.7643 NPC265335
Intermediate Similarity 0.7642 NPC259554
Intermediate Similarity 0.7638 NPC316062
Intermediate Similarity 0.763 NPC241354
Intermediate Similarity 0.7627 NPC471576
Intermediate Similarity 0.7615 NPC471877
Intermediate Similarity 0.7609 NPC37065
Intermediate Similarity 0.7603 NPC128730
Intermediate Similarity 0.7603 NPC238115
Intermediate Similarity 0.7597 NPC264976
Intermediate Similarity 0.7589 NPC476191
Intermediate Similarity 0.7578 NPC45104
Intermediate Similarity 0.7574 NPC249425
Intermediate Similarity 0.7563 NPC107101
Intermediate Similarity 0.7561 NPC291837
Intermediate Similarity 0.7557 NPC475839
Intermediate Similarity 0.7556 NPC210674
Intermediate Similarity 0.7554 NPC281169
Intermediate Similarity 0.7554 NPC291119
Intermediate Similarity 0.7541 NPC1065
Intermediate Similarity 0.7541 NPC326801
Intermediate Similarity 0.754 NPC109241
Intermediate Similarity 0.754 NPC303522
Intermediate Similarity 0.7538 NPC31314
Intermediate Similarity 0.7538 NPC473290
Intermediate Similarity 0.7538 NPC193193
Intermediate Similarity 0.7538 NPC471504
Intermediate Similarity 0.7536 NPC205915
Intermediate Similarity 0.752 NPC233238
Intermediate Similarity 0.752 NPC245552
Intermediate Similarity 0.7519 NPC75432
Intermediate Similarity 0.7519 NPC111088
Intermediate Similarity 0.7519 NPC474237
Intermediate Similarity 0.7518 NPC258073
Intermediate Similarity 0.75 NPC9341
Intermediate Similarity 0.75 NPC474599
Intermediate Similarity 0.75 NPC188997
Intermediate Similarity 0.75 NPC33717
Intermediate Similarity 0.75 NPC307425
Intermediate Similarity 0.75 NPC476748
Intermediate Similarity 0.75 NPC81067
Intermediate Similarity 0.75 NPC149545
Intermediate Similarity 0.75 NPC90577
Intermediate Similarity 0.7482 NPC176814
Intermediate Similarity 0.7482 NPC68779
Intermediate Similarity 0.7482 NPC300776
Intermediate Similarity 0.7482 NPC4982
Intermediate Similarity 0.7482 NPC5310
Intermediate Similarity 0.7481 NPC95034
Intermediate Similarity 0.7481 NPC267064
Intermediate Similarity 0.7481 NPC142087
Intermediate Similarity 0.7465 NPC79372
Intermediate Similarity 0.7464 NPC317601
Intermediate Similarity 0.7464 NPC329427
Intermediate Similarity 0.7462 NPC43435
Intermediate Similarity 0.7459 NPC288760
Intermediate Similarity 0.7445 NPC476399
Intermediate Similarity 0.7445 NPC307042
Intermediate Similarity 0.7445 NPC79184
Intermediate Similarity 0.7444 NPC21238
Intermediate Similarity 0.7444 NPC261992
Intermediate Similarity 0.7442 NPC325295
Intermediate Similarity 0.7442 NPC471503
Intermediate Similarity 0.7442 NPC471498
Intermediate Similarity 0.7442 NPC76308
Intermediate Similarity 0.7442 NPC240664
Intermediate Similarity 0.744 NPC231251
Intermediate Similarity 0.744 NPC88868
Intermediate Similarity 0.744 NPC25067
Intermediate Similarity 0.7438 NPC179686
Intermediate Similarity 0.7431 NPC470273
Intermediate Similarity 0.7429 NPC211386
Intermediate Similarity 0.7429 NPC113295
Intermediate Similarity 0.7429 NPC161856
Intermediate Similarity 0.7429 NPC51087
Intermediate Similarity 0.7424 NPC476165
Intermediate Similarity 0.7422 NPC322358
Intermediate Similarity 0.7405 NPC474874
Intermediate Similarity 0.7405 NPC168050
Intermediate Similarity 0.7402 NPC190212
Intermediate Similarity 0.7402 NPC165106
Intermediate Similarity 0.7395 NPC470161
Intermediate Similarity 0.7394 NPC307883
Intermediate Similarity 0.7388 NPC140521
Intermediate Similarity 0.7388 NPC89630
Intermediate Similarity 0.7377 NPC241224
Intermediate Similarity 0.7377 NPC109637
Intermediate Similarity 0.7376 NPC307401
Intermediate Similarity 0.7376 NPC92932
Intermediate Similarity 0.7372 NPC238309
Intermediate Similarity 0.736 NPC234639
Intermediate Similarity 0.7357 NPC19890
Intermediate Similarity 0.7357 NPC27394
Intermediate Similarity 0.7357 NPC110958
Intermediate Similarity 0.7355 NPC300166
Intermediate Similarity 0.7353 NPC298884
Intermediate Similarity 0.7348 NPC212559
Intermediate Similarity 0.7343 NPC76312
Intermediate Similarity 0.7339 NPC35543
Intermediate Similarity 0.7339 NPC258171
Intermediate Similarity 0.7333 NPC280767
Intermediate Similarity 0.7333 NPC289459
Intermediate Similarity 0.7333 NPC249836
Intermediate Similarity 0.7329 NPC290038
Intermediate Similarity 0.7328 NPC471449
Intermediate Similarity 0.7328 NPC37858
Intermediate Similarity 0.7324 NPC281780
Intermediate Similarity 0.7324 NPC471542
Intermediate Similarity 0.7323 NPC474920
Intermediate Similarity 0.7323 NPC26615
Intermediate Similarity 0.7319 NPC2989
Intermediate Similarity 0.7319 NPC475880
Intermediate Similarity 0.7317 NPC139891
Intermediate Similarity 0.7317 NPC470393
Intermediate Similarity 0.7308 NPC185738
Intermediate Similarity 0.7305 NPC475011
Intermediate Similarity 0.7305 NPC44245
Intermediate Similarity 0.7305 NPC72796
Intermediate Similarity 0.7302 NPC475852
Intermediate Similarity 0.7302 NPC2682
Intermediate Similarity 0.7299 NPC474623
Intermediate Similarity 0.7299 NPC474651
Intermediate Similarity 0.7299 NPC226661
Intermediate Similarity 0.7295 NPC192596
Intermediate Similarity 0.7295 NPC298224
Intermediate Similarity 0.7295 NPC24327
Intermediate Similarity 0.7295 NPC12870
Intermediate Similarity 0.7293 NPC312713
Intermediate Similarity 0.7293 NPC126935
Intermediate Similarity 0.7293 NPC65933
Intermediate Similarity 0.7293 NPC216929
Intermediate Similarity 0.7293 NPC172676
Intermediate Similarity 0.7293 NPC57268
Intermediate Similarity 0.7292 NPC155552
Intermediate Similarity 0.7292 NPC100675
Intermediate Similarity 0.7292 NPC472523
Intermediate Similarity 0.7288 NPC471581
Intermediate Similarity 0.7287 NPC296526
Intermediate Similarity 0.7287 NPC47194
Intermediate Similarity 0.7287 NPC475815
Intermediate Similarity 0.7287 NPC473264
Intermediate Similarity 0.7287 NPC283169
Intermediate Similarity 0.7287 NPC301321
Intermediate Similarity 0.728 NPC201959
Intermediate Similarity 0.728 NPC75440
Intermediate Similarity 0.728 NPC245115
Intermediate Similarity 0.7279 NPC474476
Intermediate Similarity 0.7279 NPC101894
Intermediate Similarity 0.7279 NPC213552
Intermediate Similarity 0.7279 NPC120225
Intermediate Similarity 0.7273 NPC14177
Intermediate Similarity 0.7273 NPC202260
Intermediate Similarity 0.7259 NPC470163
Intermediate Similarity 0.7259 NPC248557
Intermediate Similarity 0.7259 NPC78446
Intermediate Similarity 0.7259 NPC470162
Intermediate Similarity 0.7259 NPC221798
Intermediate Similarity 0.7259 NPC246704
Intermediate Similarity 0.7258 NPC30416
Intermediate Similarity 0.7254 NPC90431
Intermediate Similarity 0.7254 NPC474610
Intermediate Similarity 0.7252 NPC474040
Intermediate Similarity 0.7252 NPC205502
Intermediate Similarity 0.7248 NPC95526
Intermediate Similarity 0.7246 NPC206028
Intermediate Similarity 0.7244 NPC275627
Intermediate Similarity 0.7244 NPC54626
Intermediate Similarity 0.7241 NPC46180
Intermediate Similarity 0.7239 NPC302211
Intermediate Similarity 0.7239 NPC16922
Intermediate Similarity 0.7236 NPC12987
Intermediate Similarity 0.7236 NPC474603
Intermediate Similarity 0.7236 NPC108875

Drug Structure

External Identifiers

TTD   DAP001235
DrugBank   DB04930
ChEMBL   CHEMBL1525
IUPHAR/BPS  
PharmaGKB   PA164743137
KEGG Drug   D05443
PubChem CID   40326
ChEBI   34911
CAS Number  52645-53-1

Drug Properties

Molecular Weight  390.08
ALogP  1.8533
MLogP  3.22
XLogP  7.313
HDA  2
HBD  0
Rotatable Bonds  11
TPSA  35.53
RO5 Violation  1