Plant ID: NPO28159
Plant Latin Name: Rubia Akane
Taxonomy Genus: Rubia
Taxonomy Family: Rubiaceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Antitumor; Emmenagogue; Haemostatic
South Korea
Ingredient ID: NPC99240
Ingredient ID: NPC96625
Ingredient ID: NPC95427
Ingredient ID: NPC95006
Ingredient ID: NPC92125
Ingredient ID: NPC88955
Ingredient ID: NPC87857
Ingredient ID: NPC87231
Ingredient ID: NPC86191
Ingredient ID: NPC78924
Ingredient ID: NPC74584
Ingredient ID: NPC73416
Ingredient ID: NPC73061
Ingredient ID: NPC72452
Ingredient ID: NPC70853
Ingredient ID: NPC70756
Ingredient ID: NPC67660
Ingredient ID: NPC67118
Ingredient ID: NPC65920
Ingredient ID: NPC6198
Ingredient ID: NPC61546
Ingredient ID: NPC61
Ingredient ID: NPC60389
Ingredient ID: NPC53414
Ingredient ID: NPC47993
Ingredient ID: NPC475246
Ingredient ID: NPC475161
Ingredient ID: NPC44437
Ingredient ID: NPC40118
Ingredient ID: NPC3718
Ingredient ID: NPC35836
Ingredient ID: NPC34877
Ingredient ID: NPC33666
Ingredient ID: NPC3357
Ingredient ID: NPC310259
Ingredient ID: NPC298711
Ingredient ID: NPC296631
Ingredient ID: NPC296556
Ingredient ID: NPC296206
Ingredient ID: NPC294226
Ingredient ID: NPC29353
Ingredient ID: NPC293378
Ingredient ID: NPC29210
Ingredient ID: NPC291044
Ingredient ID: NPC289758
Ingredient ID: NPC286544
Ingredient ID: NPC279032
Ingredient ID: NPC278556
Ingredient ID: NPC273417
Ingredient ID: NPC270617
Ingredient ID: NPC269783
Ingredient ID: NPC265041
Ingredient ID: NPC264160
Ingredient ID: NPC263670
Ingredient ID: NPC262094
Ingredient ID: NPC253422
Ingredient ID: NPC253352
Ingredient ID: NPC248056
Ingredient ID: NPC246558
Ingredient ID: NPC243083
Ingredient ID: NPC242895
Ingredient ID: NPC238629
Ingredient ID: NPC237532
Ingredient ID: NPC236769
Ingredient ID: NPC231410
Ingredient ID: NPC225153
Ingredient ID: NPC222455
Ingredient ID: NPC222342
Ingredient ID: NPC216111
Ingredient ID: NPC213935
Ingredient ID: NPC210809
Ingredient ID: NPC21079
Ingredient ID: NPC210375
Ingredient ID: NPC205093
Ingredient ID: NPC200137
Ingredient ID: NPC195360
Ingredient ID: NPC193703
Ingredient ID: NPC19256
Ingredient ID: NPC192402
Ingredient ID: NPC19044
Ingredient ID: NPC18074
Ingredient ID: NPC175738
Ingredient ID: NPC17432
Ingredient ID: NPC170011
Ingredient ID: NPC16728
Ingredient ID: NPC167140
Ingredient ID: NPC165198
Ingredient ID: NPC157514
Ingredient ID: NPC155550
Ingredient ID: NPC152985
Ingredient ID: NPC151442
Ingredient ID: NPC150648
Ingredient ID: NPC142956
Ingredient ID: NPC142891
Ingredient ID: NPC1397
Ingredient ID: NPC130683
Ingredient ID: NPC130130
Ingredient ID: NPC129132
Ingredient ID: NPC127447
Ingredient ID: NPC126534
Ingredient ID: NPC119725
Ingredient ID: NPC115376
Ingredient ID: NPC114610
Ingredient ID: NPC113212
Ingredient ID: NPC103904
Ingredient ID: NPC101294
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Drug Transporter | ATP-binding cassette | ABCG2 | ATP-binding cassette sub-family G member 2 | Q9UNQ0 | CHEMBL5393 |
Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
Cytochrome P450 | Cytochrome P450 family 19 | CYP19A1 | Cytochrome P450 19A1 | P11511 | CHEMBL1978 |
Cytochrome P450 | Cytochrome P450 family 2 | CYP2C19 | Cytochrome P450 2C19 | P33261 | CHEMBL3622 |
Therapeutic Target | Enzyme | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | P27695 | CHEMBL5619 |
Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Therapeutic Target | Potassium channels | KCNA3 | Voltage-gated potassium channel subunit Kv1.3 | P22001 | CHEMBL4633 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Unclassified protein | SNCA | Alpha-synuclein | P37840 | CHEMBL6152 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 100 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT03205553 | Direct Peritoneal Resuscitation in Gastroschisis | gastroschisis | Glucose, Liquid (NPC289758) | NP level |
NCT04557878 | Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction | temporomandibular joint disorder | Glucose, Liquid (NPC289758) | NP level |
NCT04791202 | Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis | pain | Glucose, Liquid (NPC289758) | NP level |
NCT01557296 | Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
NCT04409665 | The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST) | respiratory failure | Glucose, Liquid (NPC289758) | NP level |
NCT03718507 | Study on the Effects of Different Premedication for LISA on Stress and Cerebral Tissue Oxygenation in Preterm Infants | acute respiratory distress syndrome | Sucrose (NPC130683) | NP level |
NCT02910518 | A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT00835939 | Treatment for Achilles Tendinopathy | Tendinopathy | Glucose, Liquid (NPC289758) | NP level |
NCT03241706 | Liver Glycogen and Hypoglycemia in Humans | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
NCT03272594 | The Influence of Breastfeeding on Cortical Activity During Procedures | pain | Sucrose (NPC130683) | NP level |
NCT05029037 | High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. | COVID-19 | Glucose, Liquid (NPC289758) | NP level |
NCT01421160 | Regulating Urine pH Levels to Alleviate Chronic Joint Pain | osteoarthritis | Citric Acid (NPC293378) | NP level |
NCT01547364 | Caudal Epidural Injection of Dextrose For Low Back Pain | Low back pain | Glucose, Liquid (NPC289758) | NP level |
NCT02086864 | A Placebo Controlled Study of Homeopathic Treatment of Children and Youth With ADHD | attention deficit hyperactivity disorder | Sucrose (NPC130683) | NP level |
NCT02800161 | Trehalose as add-on Therapy in Bipolar Depression | bipolar disorder | Maltose (NPC246558) | NP level |
NCT01238471 | Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study | retinopathy of prematurity | Sucrose (NPC130683) | NP level |
NCT01883440 | Glucose Oxidase as Treatment Against Common Cold | common cold | Glucose, Liquid (NPC289758) | NP level |
NCT02710266 | Evaluation of the Effect of Gabexate Mesilate in the Hepatocyte Protection After Liver Resection | liver disease | Glucose, Liquid (NPC289758) | NP level |
NCT03337477 | A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 | Hyperkalemia | Glucose, Liquid (NPC289758) | NP level |
NCT04832009 | Reversing Glucose and Lipid-mediated Vascular Dysfunction | hypertension | Glucose, Liquid (NPC289758) | NP level |
NCT01121354 | Pharmacokinetics and Safety of Cefazolin 2g in DUPLEX | infection | Glucose, Liquid (NPC289758) | NP level |
NCT01548612 | Add-on Sodium Nitroprusside to Treatment as Usual in Schizophrenia | schizophrenia | Glucose, Liquid (NPC289758) | NP level |
NCT02728037 | Magnesium-Based Trigger Point Injections for Relief of Chronic Myofascial Pelvic Pain | pain | Glucose, Liquid (NPC289758) | NP level |
NCT00617552 | Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery | ileus | Glucose, Liquid (NPC289758) | NP level |
NCT00213759 | Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSF | neutropenia | Glucose, Liquid (NPC289758) | NP level |
NCT03745963 | The Influence of Skin-to-skin Contact on Cortical Activity During Painful Procedures on Preterm Infants in the NICU | pain | Sucrose (NPC130683) | NP level |
NCT01562626 | Phase I/II Study of APS001F With Flucytosine and Maltose in Solid Tumors | cancer | Maltose (NPC246558) | NP level |
NCT01485315 | Transfusion-requirements in Septic Shock Trial | septic shock | Glucose, Liquid (NPC289758) | NP level |
NCT00218946 | Nasogastric Tube in Premature Babies - Pain and Treatment | premature birth | Sucrose (NPC130683) | NP level |
NCT05160532 | Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
NCT01753882 | Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI) | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
NCT01223690 | Clarithromycin as Immunomodulator for the Management of Sepsis | Sepsis;septic shock | Glucose, Liquid (NPC289758) | NP level |
NCT02054325 | Study Protocol Comparing Polidocanol Versus Hypertonic Glucose for Treatment of Reticular Veins | Varicose veins | Glucose, Liquid (NPC289758) | NP level |
NCT02591927 | Reappraisal of GIK in Acute STEMI by Pre-hospital Administration | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
NCT00787059 | AC6 Gene Transfer for CHF | congestive heart failure | Sucrose (NPC130683) | NP level |
NCT02990364 | Combination Analgesia for Neonatal Circumcision | pain | Sucrose (NPC130683) | NP level |
NCT03082001 | Sucrose to Reduce Pain During Initiation of Venipuncture in Extremely Low Birth Weight Babies | pain | Sucrose (NPC130683) | NP level |
NCT00800085 | Beta Cell Function in (Pre) Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT04133922 | Effect of GLP-1 on Microvascular Insulin Responses in Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT05424315 | Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
NCT01251770 | Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
NCT00519207 | Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture | pain | Sucrose (NPC130683) | NP level |
NCT00632775 | 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
NCT02325583 | Intraoral 30% Glucose Effect In Newborns | epilepsy | Glucose, Liquid (NPC289758) | NP level |
NCT03778593 | FOLFIRINOX for 2nd-line Treatment of BTC | biliary tract cancer | Glucose, Liquid (NPC289758) | NP level |
NCT01075984 | Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for Invasive Fungal Infections (P05520) | fungal infectious disease | Glucose, Liquid (NPC289758) | NP level |
NCT03357666 | Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis | bacterial vaginosis | Glucose, Liquid (NPC289758) | NP level |
NCT00686608 | Hypothalamic Functional Magnetic Resonance Imaging (fMRI) Response to Nutrients | obesity | Glucose, Liquid (NPC289758) | NP level |
NCT00617981 | Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC) | hepatocellular carcinoma | Glucose, Liquid (NPC289758) | NP level |
NCT03039673 | MIROCALS: Modifying Immune Response and OutComes in ALS | amyotrophic lateral sclerosis | Glucose, Liquid (NPC289758) | NP level |
NCT03690583 | Immunomodulation by Zinc Supplementation in Children With Pneumonia | pneumonia | Glucose, Liquid (NPC289758) | NP level |
NCT00091507 | IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium. | congestive heart failure;intermediate coronary syndrome;myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
NCT00612014 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
NCT02174705 | Rotavirus vs. Sucrose for Vaccine Injection Pain | pain | Sucrose (NPC130683) | NP level |
NCT03860688 | Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins | hyperlipidemia | Glucose, Liquid (NPC289758) | NP level |
NCT00639808 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
NCT01307904 | The Glycemic Indices of Five Common Varieties of Dates in the Tested Among Healthy and Diabetic Subjects | diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT01012349 | Efficacy and Safety Clinical Trial of the Combination of Acetylsalicylic Acid, Sodium Bicarbonate and Citric Acid, Produced by Geolab Pharmaceutical Industries Ltd., Compared to Acetylsalicylic Acid (Aspirin ® - Bayer) in Patients With Episodic Tension-type Headache. | Tension-type headache | Citric Acid (NPC293378) | NP level |
NCT00552786 | Antioxidation Medication for Noise-induced Hearing Loss | hearing loss | Glucose, Liquid (NPC289758) | NP level |
NCT01909336 | Use of Isotonic Solutions Versus Hypotonic Solutions for Preventing Hospital Acquired Hyponatremia | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
NCT02596477 | Evaluation of Vepoloxamer in Chronic Heart Failure | heart failure | Glucose, Liquid (NPC289758) | NP level |
NCT00249951 | Alkaline Citrate Treatment to Lower the Risk of Nephrocalcinosis in Preterm Infants | Nephrocalcinosis | Citric Acid (NPC293378) | NP level |
NCT04918719 | Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke | Ischemic stroke | Glucose, Liquid (NPC289758) | NP level |
NCT04001036 | Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
NCT03024814 | Prophylactic Acetaminophen for Prevention Intraventricular Hemorrhage in Premature Infants | hemorrhage | Glucose, Liquid (NPC289758) | NP level |
NCT04726436 | Dextrose Effect on Postoperative Nausea and Vomiting (PONV) | post operative nausea and vomiting | Glucose, Liquid (NPC289758) | NP level |
NCT01788969 | Serotonergic Modulation of Motor Function in Subacute and Chronic SCI | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
NCT03577730 | Caffeine and Neurologic Recovery Following Surgery and General Anesthesia | pain | Glucose, Liquid (NPC289758) | NP level |
NCT01561547 | Trial of Repeated Analgesia With Kangaroo Care | pain | Sucrose (NPC130683) | NP level |
NCT00949104 | Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preterm Neonates | pain | Sucrose (NPC130683) | NP level |
NCT02059785 | Phase ⅡStudy of Pinocembrin Injection to Treat Ischemic Stroke | Ischemic stroke | Pinocembrin (NPC243083) | NP level |
NCT01602068 | Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL | cataract | Citric Acid (NPC293378) | NP level |
NCT01503060 | Effectiveness of Parent-Led Interventions in Reducing Infant Hypersensitivity to Pain | pain | Sucrose (NPC130683) | NP level |
NCT02678208 | The Effect of Tranexamic Acid on Uterine Blood Flow After Vaginal Delivery | postpartum hemorrhage | Glucose, Liquid (NPC289758) | NP level |
NCT00482560 | Analgesic Effect of Breast Feeding vs Sucrose in Neonatal Screening | pain | Sucrose (NPC130683) | NP level |
NCT01754779 | Treatment for Calcium Phosphate Kidney Stone Disease | nephrolithiasis | Citric Acid (NPC293378) | NP level |
NCT02269735 | A Three-part Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-2640 in Healthy Participants (Part I) and Participants With Type 1 Diabetes Mellitus (Parts II and III) (MK-2640-001) | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT01210183 | Biological Response of Stage IV Knee Osteoarthritis to Serial 12.5% Dextrose | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
NCT02632630 | Nutrition Supplementation in Hospitalized Patients | malnutrition | Glucose, Liquid (NPC289758) | NP level |
NCT01201954 | Pain Relief of Newborn Preterm Infants During Endotracheal Suctioning | pain | Sucrose (NPC130683) | NP level |
NCT01962116 | Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU | Renal insufficiency | Citric Acid (NPC293378) | NP level |
NCT03994471 | Efficacy and Safety of XyloCore Peritoneal Dialysis Solution. | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
NCT05326763 | Functional and Electromyographical Changes After PRP or Dextrose Injection in Chronic Lateral Epicondylitis | lateral epicondylitis | Glucose, Liquid (NPC289758) | NP level |
NCT04677829 | Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI) | brain injury | Glucose, Liquid (NPC289758) | NP level |
NCT04895358 | Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49) | breast neoplasm | Glucose, Liquid (NPC289758) | NP level |
NCT00337597 | Continuous Regional Analgesia After Total Knee Arthroplasty | pain | Glucose, Liquid (NPC289758) | NP level |
NCT02752308 | Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair | hypospadias | Glucose, Liquid (NPC289758) | NP level |
NCT01190995 | Role of Repeated Painful Procedures in Preterm Neonates on Short Term Neurobehavioural Outcome | pain | Sucrose (NPC130683) | NP level |
NCT00062972 | Improving Memory in Patients With Multiple Sclerosis | multiple sclerosis | Glucose, Liquid (NPC289758) | NP level |
NCT04088591 | High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda | Sepsis | Glucose, Liquid (NPC289758) | NP level |
NCT04855266 | Iron Sucrose in Patients With Iron Deficiency and POTS | orthostatic hypotension | Sucrose (NPC130683) | NP level |
NCT05185999 | Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
NCT05205486 | Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults | infection | Glucose, Liquid (NPC289758) | NP level |
NCT02319512 | Effects of Chewing Gum Against Postoperative Ileus | ileus | Glucose, Liquid (NPC289758) | NP level |
NCT01300260 | Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose | type 2 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT02180412 | Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria | porphyria | Glucose, Liquid (NPC289758) | NP level |
NCT02866435 | Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
NCT02374281 | Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking | pain | Glucose, Liquid (NPC289758) | NP level |
NCT02185729 | Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunteers | metabolic disease | Glucose, Liquid (NPC289758) | NP level |
NCT00823108 | Rapid Administration of Insulin in Sepsis | septic shock | Glucose, Liquid (NPC289758) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
KCNA3,SNCA,CYP1B1,POLB,ABCG2,LMNA,CYP2C19
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
MAPK1,POLB,APEX1,ESR1,PKM
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
APEX1,KCNA3,SNCA,TDP1,LMNA
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT00800085,NCT02269735,NCT04133922,NCT02910518
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
PKM,POLB,TDP1,CYP19A1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
APEX1,PKM,ESR1,TDP1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
CYP19A1,PKM,CYP19A1,PKM
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
MAPK1,KCNA3,SNCA,ABCG2
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT05185999,NCT04001036,NCT03994471
|
Hypo-kalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C77 |
NCT01251770,NCT01909336,NCT00632775
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT05424315,NCT02591927,NCT00091507
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT00823108,NCT01485315,NCT01223690
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT01210183,NCT01421160,NCT05160532
|
GastroparesisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41.00 |
NCT00612014,NCT01557296,NCT00639808
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
APEX1,TDP1,LMNA
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
APEX1,KCNA3,CYP1B1
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CYP1B1,LMNA,CYP19A1
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
ESR1
NCT00062972 |
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
SNCA,MAOA
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
ESR1
NCT01307904 |
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SNCA,MAOA
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
MAOA,ESR1
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
ESR1,CYP19A1
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CYP19A1,ESR1
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT01121354,NCT05205486
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT04088591,NCT01223690
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00091507,NCT00787059
|
Injury of spinal cord, level unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51.2 |
NCT01788969,NCT01753882
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
NCT02059785,NCT04918719
|
Postoperative ileusDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA91-DB30 |
NCT02319512,NCT00617552
|
Hypoglycaemia without associated diabetesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A41 |
NCT02866435,NCT03241706
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
SNCA,KCNA3
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
MAOA,ABCG2
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
PKM,LMNA
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
CYP19A1,PKM
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
KCNA3,ABCG2
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
SNCA,LMNA
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
KCNA3,CYP2C19
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA,CYP19A1
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1,ABCG2
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
CYP1B1,ESR1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
SNCA,CYP19A1
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
PKM
NCT00337597,NCT03745963,NCT03272594,NCT04791202,NCT01561547,NCT00949104,NCT01201954,NCT02174705,NCT03577730,NCT02374281,NCT00482560,NCT02728037,NCT01503060,NCT03082001,NCT02990364,NCT00519207,NCT01190995 |
Psoriatic arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA21 |
KCNA3
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ESR1
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
MAOA
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
PKM
|
Skin tag/polypDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK71 |
MAOA
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ABCG2
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
ESR1
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
MAPK1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
ESR1
|
Idiopathic inflammatory myopathyDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A41 |
KCNA3
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR1
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
MAPK1
|
Ocular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D00-2D07 |
APEX1
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
MAOA
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
ABCG2
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
MAOA
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ESR1
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
KCNA3
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
CYP19A1
|
Autonomic nervous system disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87 |
SNCA
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
ESR1
|
Arteries/arterioles disorderDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD52 |
MAPK1
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
APEX1
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
MAOA
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
MAOA
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
CYP19A1
|
Diseases of the musculoskeletal system or connective tissue, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FC0Z |
NCT00835939
|
Lateral epicondylitis of elbowDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB55.1 |
NCT05326763
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
NCT04855266
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
NCT02325583
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT04832009
|
HyperkalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C76 |
NCT03337477
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT03718507
|
Temporomandibular joint disordersDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0E.8 |
NCT04557878
|
Kidney failure, unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB6Z |
NCT01962116
|
Retinopathy of prematurityDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71.3 |
NCT01238471
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
NCT02086864
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
NCT00686608
|
Skin fungal infection disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA60 |
NCT01075984
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB10Z |
NCT02710266
|
PolyuriaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF55 |
NCT02180412
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
NCT04726436
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
NCT02800161
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
NCT02596477
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
NCT01548612
|
Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT03024814
|
GastroschisisDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB02 |
NCT03205553
|
Low back painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84.2 |
NCT01547364
|
CholelithiasisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC11 |
NCT01754779
|
Respiratory failureDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB41 |
NCT04409665
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT04895358
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
NCT03860688
|
Preterm newborn, unspecifiedDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA21.4Z |
NCT00218946
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT03690583
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
NCT03778593
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT01562626
|
Tension-type headacheDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A81 |
NCT01012349
|
Vaginal dischargeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF3A |
NCT03357666
|
NeutropeniaDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B00 |
NCT00213759
|
Common cold disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SA60 |
NCT01883440
|
Varicose veinsDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD74-BD75 |
NCT02054325
|
NephrocalcinosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB57 |
NCT00249951
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
NCT02185729
|
Intracranial injury, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.Z |
NCT04677829
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT02632630
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
NCT01602068
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT03039673
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NCT01300260
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT05029037
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
NCT02678208
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT00617981
|
Unstable anginaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40.0 |
NCT00091507
|
HypospadiasDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB53 |
NCT02752308
|
Hearing disorderDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB50-AB57 |
NCT00552786
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
KCNA3
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
CYP19A1
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
CYP19A1
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
CYP19A1
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
ABCG2
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CYP1B1
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
PKM
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
ESR1
|