Ingredient ID: NPC81983
Ingredient ID: NPC80439
Ingredient ID: NPC72840
Ingredient ID: NPC4872
Ingredient ID: NPC469352
Ingredient ID: NPC469351
Ingredient ID: NPC469350
Ingredient ID: NPC41674
Ingredient ID: NPC37407
Ingredient ID: NPC327181
Ingredient ID: NPC32189
Ingredient ID: NPC306765
Ingredient ID: NPC297271
Ingredient ID: NPC289258
Ingredient ID: NPC283114
Ingredient ID: NPC276026
Ingredient ID: NPC268391
Ingredient ID: NPC262557
Ingredient ID: NPC256
Ingredient ID: NPC230538
Ingredient ID: NPC228612
Ingredient ID: NPC217708
Ingredient ID: NPC215650
Ingredient ID: NPC207702
Ingredient ID: NPC206737
Ingredient ID: NPC197479
Ingredient ID: NPC185680
Ingredient ID: NPC184684
Ingredient ID: NPC182185
Ingredient ID: NPC172823
Ingredient ID: NPC172171
Ingredient ID: NPC171530
Ingredient ID: NPC163693
Ingredient ID: NPC162024
Ingredient ID: NPC149008
Ingredient ID: NPC147635
Ingredient ID: NPC145722
Ingredient ID: NPC135594
Ingredient ID: NPC133934
Ingredient ID: NPC130319
Ingredient ID: NPC126405
Ingredient ID: NPC105227
Ingredient ID: NPC103637
Ingredient ID: NPC102256
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials |
---|
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
TDP1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
TDP1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
TDP1
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
TDP1
|